Search Results - "Grishanova, Alevtina Y"

Aryl Hydrocarbon Receptor in Oxidative Stress as a Double Agent and Its Biological and Therapeutic Significance by Grishanova, Alevtina Y, Perepechaeva, Maria L

“…The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery of genes involved in the metabolism of xenobiotics and endogenous…”
Get full text

Kynurenic Acid/AhR Signaling at the Junction of Inflammation and Cardiovascular Diseases by Grishanova, Alevtina Y, Perepechaeva, Maria L

“…Persistent systemic chronic inflammatory conditions are linked with many pathologies, including cardiovascular diseases (CVDs), a leading cause of death across…”
Get full text

The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors by Perepechaeva, Maria L, Grishanova, Alevtina Y

“…Primary brain tumors, both malignant and benign, are diagnosed in adults at an incidence rate of approximately 23 people per 100 thousand. The role of AhR in…”
Get full text

AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay by Grishanova, Alevtina Y, Klyushova, Lyubov S, Perepechaeva, Maria L

“…As evolutionarily conserved signaling cascades, AhR and Wnt signaling pathways play a critical role in the control over numerous vital embryonic and somatic…”
Get full text

The Role of CYP3A in Health and Disease by Klyushova, Lyubov S, Perepechaeva, Maria L, Grishanova, Alevtina Y

“…CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are…”
Get full text

AhR and HIF-1α Signaling Pathways in Benign Meningioma under Hypoxia by Perepechaeva, Maria L., Klyushova, Lyubov S., Grishanova, Alevtina Y.

“…The role of hypoxia in benign meningiomas is less clear than that in the malignant meningiomas. Hypoxia-induced transcription factor 1 subunit alpha (HIF-1α)…”
Get full text

Antioxidant Activity of New Sulphur- and Selenium-Containing Analogues of Potassium Phenosan against H2O2-Induced Cytotoxicity in Tumour Cells by Klyushova, Lyubov S., Kandalintseva, Natalya V., Grishanova, Alevtina Y.

“…Among known phenolic antioxidants, the overwhelming majority of compounds have lipophilic properties and the number of known water-soluble compounds is very…”
Get full text

The Expression of Genes CYP1A1 , CYP1B1 , and CYP2J3 in Distinct Regions of the Heart and Its Possible Contribution to the Development of Hypertension by Perepechaeva, Maria L, Stefanova, Natalia A, Grishanova, Alevtina Y, Kolosova, Nataliya G

“…It is believed that alterations in the functioning of the cytochrome P450 (CYP), which participates in metabolic transformations of endogenous polyunsaturated…”
Get full text

Menadione Suppresses Benzo(α)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism by Sidorova, Yulia A, Perepechaeva, Maria L, Pivovarova, Elena N, Markel, Arkady L, Lyakhovich, Vyacheslav V, Grishanova, Alevtina Y

“…Oxidative reactions that are catalyzed by cytochromes P450 1A (CYP1A) lead to formation of carcinogenic derivatives of arylamines and polycyclic aromatic…”
Get full text

Water-soluble copper(II) complexes with 4,5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and DNA binding study by Eremina, Julia A., Lider, Elizaveta V., Sukhikh, Taisiya S., Klyushova, Lyubov S., Perepechaeva, Maria L., Sheven', Dmitriy G., Berezin, Alexey S., Grishanova, Alevtina Y., Potkin, Vladimir I.

“…Mixed-ligand copper(II) complexes with 4,5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands as potential anticancer agents. [Display…”
Get full text

Antioxidant Activity of New Sulphur- and Selenium-Containing Analogues of Potassium Phenosan against H 2 O 2 -Induced Cytotoxicity in Tumour Cells by Klyushova, Lyubov S, Kandalintseva, Natalya V, Grishanova, Alevtina Y

“…Among known phenolic antioxidants, the overwhelming majority of compounds have lipophilic properties and the number of known water-soluble compounds is very…”
Get full text

Menadione Suppresses Benzopyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism by Sidorova, Yulia A, Perepechaeva, Maria L, Pivovarova, Elena N, Markel, Arkady L, Lyakhovich, Vyacheslav V, Grishanova, Alevtina Y

“…Oxidative reactions that are catalyzed by cytochromes P450 1A (CYP1A) lead to formation of carcinogenic derivatives of arylamines and polycyclic aromatic…”
Get full text

Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients by Seredina, Tatyana A, Goreva, Olga B, Talaban, Valeria O, Grishanova, Alevtina Yu, Lyakhovich, Vyacheslav V

“…The enzymes of the cytochrome P450 family (CYPs) play an important role in the metabolism of a great variety of anticancer agents; therefore, polymorphisms in…”
Get full text