Search Results - "Grippo, P."

TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function by Principe, D R, Diaz, A M, Torres, C, Mangan, R J, DeCant, B, McKinney, R, Tsao, M-S, Lowy, A, Munshi, H G, Jung, B, Grippo, P J

“…While TGFβ signals are anti-proliferative in benign and well-differentiated pancreatic cells, TGFβ appears to promote the progression of advanced cancers. To…”
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Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression by Dangi-Garimella, S, Strouch, M J, Grippo, P J, Bentrem, D J, Munshi, H G

“…Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced collagen-rich fibrosis known as desmoplastic reaction; however, the role of fibrosis in…”
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Collagen regulation of let-7 in pancreatic cancer involves TGF- beta 1-mediated membrane type 1-matrix metalloproteinase expression by Dangi-Garimella, S, Strouch, M J, Grippo, P J, Bentrem, D J, Munshi, H G

“…Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced collagen-rich fibrosis known as desmoplastic reaction; however, the role of fibrosis in…”
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tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1 by Giordano, A, Calvani, M, Petillo, O, Grippo, P, Tuccillo, F, Melone, M A B, Bonelli, P, Calarco, A, Peluso, G

“…Recent studies suggest a close relationship between cell metabolism and apoptosis. We have evaluated changes in lipid metabolism on permeabilized hepatocytes…”
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Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice by GRIPPE, Paul J, NOWLIN, Patrick S, DEMEURE, Michael J, LONGNECKER, Daniel S, SANDGREN, Eric P

“…Activating mutation of the Kras oncogene is the most frequent and perhaps the earliest genetic alteration associated with pancreatic cancer. To examine the…”
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Highly Invasive Transitional Cell Carcinoma of the Bladder in a Simian Virus 40 T-Antigen Transgenic Mouse Model by Grippo, Paul J., Sandgren, Eric P.

“…Transitional cell carcinoma (TCC), a neoplasm of urinary bladder urothelial cells, generally appears in either of two forms, papillary non-invasive or invasive…”
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A tensile test device for in situ atomic force microscope mechanical testing by Bamberg, Eberhard, Grippo, Christian P., Wanakamol, Panitarn, Slocum, Alexander H., Boyce, Mary C., Thomas, Edwin L.

“…The microstructure and mechanical behavior of polymeric-based materials can be controlled at the micro- and nanometer length scales through blending,…”
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TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis by Principe, D. R., Doll, J. A., Bauer, J., Jung, B., Munshi, H. G., Bartholin, L., Pasche, B., Lee, C., Grippo, P. J.

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Self-objectification, habitual body monitoring, and body dissatisfaction in older European American women: exploring age and feminism as moderators by Grippo, Karen P, Hill, Melanie S

“…This study examined the influence of feminist attitudes on self-objectification, habitual body monitoring, and body dissatisfaction in middle age and older…”
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Diet Quality and Fecal Bile Acid Composition by Oliveira, ML, Abuzer, M, Wolf, P, Cares, K, Grippo, P, Mutlu, E, Gaskins, HR, Ridion, J, Tussing-Humphreys, L

“…Background: Bile acids (BAs) are steroid metabolites generated by the liver from cholesterol. Their function is to support digestion of dietary fat,…”
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Empowerment and Powerlessness: A Closer Look at the Relationship Between Feminism, Body Image and Eating Disturbance by Peterson, Rachel D., Grippo, Karen P., Tantleff-Dunn, Stacey

“…Objectification Theory (Frederickson & Roberts, 1997) states that women’s bodies are viewed as objects to be evaluated and this societal objectification may…”
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Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice by Guerra, Carmen, Schuhmacher, Alberto J., Cañamero, Marta, Grippo, Paul J., Verdaguer, Lena, Pérez-Gallego, Lucía, Dubus, Pierre, Sandgren, Eric P., Barbacid, Mariano

“…Pancreatic ductal adenocarcinoma (PDA), one of the deadliest human cancers, often involves somatic activation of K- Ras oncogenes. We report that selective…”
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Template 2-chloro-2'-deoxyadenosine monophosphate inhibits in vitro DNA synthesis by Hentosh, P, Grippo, P

“…2'-Chloro-2'-deoxyadenosine triphosphate (cladribine), a purine nucleotide analog and potent antileukemic agent, was enzymatically incorporated into 98-base…”
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2-Chloro-2'-deoxyadenosine monophosphate residues in DNA enhance susceptibility to 3'→5' exonucleases by HENTOSH, P, GRIPPO, P

“…2-Chloro-2'-deoxyadenosine triphosphate, a purine nucleotide analogue and potent antileukaemic agent, was incorporated into double-stranded 36-mers in place of…”
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TGF[beta] engages MEK/ERK to differentially regulate benign and malignant pancreas cell function by Principe, D R, Diaz, A M, Torres, C, Mangan, R J, DeCant, B, McKinney, R, Tsao, M-S, Lowy, A, Munshi, H G, Jung, B, Grippo, P J

“…While TGF[beta] signals are anti-proliferative in benign and well-differentiated pancreatic cells, TGF[beta] appears to promote the progression of advanced…”
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Collagen regulation of let-7 in pancreatic cancer involves TGF-[beta]1-mediated membrane type 1-matrix metalloproteinase expression by Dangi-garimella, S, Strouch, M J, Grippo, P J, Bentrem, D J, Munshi, H G

“…Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced collagen-rich fibrosis known as desmoplastic reaction; however, the role of fibrosis in…”
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The computer-aided design of modular fixturing systems by Grippo, P. M., Gandhi, M. V., Thompson, B. S.

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The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice by BREMBECK, Felix H, SCHREIBER, Franz S, DERAMAUDT, Therese B, CRAIG, Linden, RHOADES, Ben, SWAIN, Gary, GRIPPO, Paul, STOFFERS, Doris A, SILBERG, Debra G, RUSTGI, Anil K

“…A frequent genetic alteration found in premalignant stages of pancreatic adenocarcinoma is K-ras oncogene point mutation. The mechanistic basis for the…”
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Role of MT1-MMP and Kras in invasive pancreatic tumors with pronounced fibrosis by Krantz, S. B., Dangi-Garimella, S., Shields, M. A., Grippo, P. J., Bentrem, D. J., Munshi, H. G.

“…Abstract only…”
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5-lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions by HENNIG, Rene, GRIPPO, Paul, DING, Xian-Zhong, RAO, Sambasiva M, BUCHLER, Markus W, FRIESS, Helmut, TALAMONTI, Mark S, BELL, Richard H, ADRIAN, Thomas E

“…Pancreatic cancer has an abysmal prognosis because of late diagnosis. Therefore, it is important to identify risk factors if we are to be able to prevent and…”
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