Search Results - "Gripp, Barbara"
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Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells
Published in The Journal of biological chemistry (01-01-2021)“…The acid sphingomyelinase/ceramide system has been shown to be important for cellular infection with at least some viruses, for instance, rhinovirus or severe…”
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Sphingosine prevents binding of SARS–CoV-2 spike to its cellular receptor ACE2
Published in The Journal of biological chemistry (06-11-2020)“…Sphingosine has been shown to prevent and eliminate bacterial infections of the respiratory tract, but it is unknown whether sphingosine can be also employed…”
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Journal Article -
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Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells
Published in Cell reports. Medicine (17-11-2020)“…The acid sphingomyelinase/ceramide system plays an important role in bacterial and viral infections. Here, we report that either pharmacological inhibition of…”
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Journal Article