Search Results - "Gripentrog, Jeannie M."

CD177-mediated nanoparticle targeting of human and mouse neutrophils by Miettinen, Heini M, Gripentrog, Jeannie M, Lord, Connie I, Nagy, Jon O

“…Neutrophils are the most abundant white blood cells, with a vital role in innate immune defense against bacterial and fungal pathogens. Although mostly…”
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Role of the carboxyl terminal di-leucine in phosphorylation and internalization of C5a receptor by Suvorova, Elena S., Gripentrog, Jeannie M., Oppermann, Martin, Miettinen, Heini M.

“…The carboxyl tail of G protein-coupled receptors contains motifs that regulate receptor interactions with intracellular partners. Activation of the human…”
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Agonist-dependent phosphorylation of the formyl peptide receptor is regulated by the membrane proximal region of the cytoplasmic tail by Suvorova, Elena S., Gripentrog, Jeannie M., Jesaitis, Algirdas J., Miettinen, Heini M.

“…Formyl peptide receptor (FPR) is a chemoattractant G protein-coupled receptor (GPCR) involved in the innate immune response against bacteria. Receptor…”
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C-Terminal Tail Phosphorylation of N-Formyl Peptide Receptor: Differential Recognition of Two Neutrophil Chemoattractant Receptors by Monoclonal Antibodies NFPR1 and NFPR2 by Riesselman, Marcia, Miettinen, Heini M, Gripentrog, Jeannie M, Lord, Connie I, Mumey, Brendan, Dratz, Edward A, Stie, Jamal, Taylor, Ross M, Jesaitis, Algirdas J

“…The N-formyl peptide receptor (FPR), a G protein-coupled receptor that binds proinflammatory chemoattractant peptides, serves as a model receptor for leukocyte…”
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Analysis of Human Phagocyte Flavocytochrome b558 by Mass Spectrometry by Taylor, Ross M., Baniulis, Danas, Burritt, James B., Gripentrog, Jeannie M., Lord, Connie I., Riesselman, Marcia H., Maaty, Walid S., Bothner, Brian P., Angel, Thomas E., Dratz, Edward A., Linton, Gilda F., Malech, Harry L., Jesaitis, Algirdas J.

“…The catalytic core of the phagocyte NADPH oxidase is a heterodimeric integral membrane protein (flavocytochrome b (Cyt b)) that generates superoxide and…”
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Different Endocytosis Pathways of the C5a Receptor and the N‐formyl Peptide Receptor by Suvorova, Elena S., Gripentrog, Jeannie M., Miettinen, Heini M.

“…Two chemoattractant receptors, C5aR (the complement fragment C5a receptor) and FPR (the N‐formyl peptide receptor), are involved in neutrophil activation at…”
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Localization of hCAP-18 on the surface of chemoattractant-stimulated human granulocytes: analysis using two novel hCAP-18-specific monoclonal antibodies by Stie, Jamal, Jesaitis, Andrew V., Lord, Connie I., Gripentrog, Jeannie M., Taylor, Ross M., Burritt, James B., Jesaitis, Algirdas J.

“…The well‐described antimicrobial and immunoregulatory properties of human cathelicidin antimicrobial protein 18 (hCAP‐18) derive in part from the ability of…”
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Experimental Evidence for Lack of Homodimerization of the G Protein-Coupled Human N-Formyl Peptide Receptor by Gripentrog, Jeannie M, Kantele, Katrin P, Jesaitis, Algirdas J, Miettinen, Heini M

“…A large number of G protein-coupled receptors have been shown to form homodimers based on a number of different techniques such as receptor…”
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Characterization of Surface Structure and p47phox SH3 Domain-Mediated Conformational Changes for Human Neutrophil Flavocytochrome b by TAYLOR, Ross M., LORD, Connie I., RIESSELMAN, Marcia H., GRIPENTROG, Jeannie M., LETO, Thomas L., MCPHAIL, Linda C., BERDICHEVSKY, Yevgeny, PICK, Edgar, JESAITIS, Algirdas J.

“…The heterodimeric, integral membrane protein flavocytochrome b (Cyt b) is the catalytic core of the phagocyte NADPH oxidase and generates superoxide which…”
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Identification of C-terminal Phosphorylation Sites of N-Formyl Peptide Receptor-1 (FPR1) in Human Blood Neutrophils by Maaty, Walid S., Lord, Connie I., Gripentrog, Jeannie M., Riesselman, Marcia, Keren-Aviram, Gal, Liu, Ting, Dratz, Edward A., Bothner, Brian, Jesaitis, Algirdas J.

“…Accumulation, activation, and control of neutrophils at inflammation sites is partly driven by N-formyl peptide chemoattractant receptors (FPRs). Occupancy of…”
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Anionic lipid-induced conformational changes in human phagocyte flavocytochrome b precede assembly and activation of the NADPH oxidase complex by Taylor, Ross M., Riesselman, Marcia H., Lord, Connie I., Gripentrog, Jeannie M., Jesaitis, Algirdas J.

“…► Reconstituted flavocytochrome b (Cyt b) was probed by fluorescent-anti-p22phox mAb. ► Free CCB-CS9 fluorescence lifetime: τ=3.8 nsec; Cyt b-bound CCB-CS9:…”
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Single-step immunoaffinity purification and characterization of dodecylmaltoside-solubilized human neutrophil flavocytochrome b by Taylor, Ross M, Burritt, James B, Foubert, Thomas R, Snodgrass, Meagan A, Stone, Kim C, Baniulis, Danas, Gripentrog, Jeannie M, Lord, Connie, Jesaitis, Algirdas J

“…Flavocytochrome b (Cyt b) is a heterodimeric, integral membrane protein that serves as the central component of an electron transferase system employed by…”
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Formyl peptide receptor-mediated ERK1/2 activation occurs through G(i) and is not dependent on beta-arrestin1/2 by Gripentrog, Jeannie M, Miettinen, Heini M

“…Formyl peptide receptor (FPR) and C5a receptor (C5aR) are chemoattractant G protein-coupled receptors (GPCRs) involved in the innate immune response against…”
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Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on β-arrestin translocation or receptor endocytosis by Gripentrog, Jeannie M., Miettinen, Heini M.

“…G protein-coupled receptors (GPCRs) transmit diverse cellular signals in response to a large number of stimuli such as chemoattractants, lipids,…”
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Variable responses of formyl peptide receptor haplotypes toward bacterial peptides by Gripentrog, Jeannie M, Mills, John S, Saari, George J, Miettinen, Heini M

“…The chemoattractant neutrophil formyl peptide receptor (FPR) binds bacterial and mitochondrial N-formylated peptides, which allows the neutrophils to find the…”
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Analysis of human phagocyte flavocytochrome b(558) by mass spectrometry by Taylor, Ross M, Baniulis, Danas, Burritt, James B, Gripentrog, Jeannie M, Lord, Connie I, Riesselman, Marcia H, Maaty, Walid S, Bothner, Brian P, Angel, Thomas E, Dratz, Edward A, Linton, Gilda F, Malech, Harry L, Jesaitis, Algirdas J

“…The catalytic core of the phagocyte NADPH oxidase is a heterodimeric integral membrane protein (flavocytochrome b (Cyt b)) that generates superoxide and…”
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Single-step immunoaffinity purification and functional reconstitution of human phagocyte flavocytochrome b by Lord, Connie I., Riesselman, Marcia H., Gripentrog, Jeannie M., Burritt, James B., Jesaitis, Algirdas J., Taylor, Ross M.

“…Human neutrophil flavocytochrome b (Cyt b) is a heterodimeric, integral membrane protein that generates high levels of superoxide in the multisubunit NADPH…”
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Characterization of Surface Structure and p47 phox SH3 Domain-Mediated Conformational Changes for Human Neutrophil Flavocytochrome b by Taylor, Ross M, Lord, Connie I, Riesselman, Marcia H, Gripentrog, Jeannie M, Leto, Thomas L, McPhail, Linda C, Berdichevsky, Yevgeny, Pick, Edgar, Jesaitis, Algirdas J

“…The heterodimeric, integral membrane protein flavocytochrome b (Cyt b) is the catalytic core of the phagocyte NADPH oxidase and generates superoxide which…”
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Identification of Putative Sites of Interaction between the Human Formyl Peptide Receptor and G Protein by Miettinen, Heini M., Gripentrog, Jeannie M., Mason, Meta M., Jesaitis, Algirdas J.

“…Wild-type and 35 mutant formyl peptide receptors (FPRs) were stably expressed in Chinese hamster ovary cells. All cell surface-expressed mutant receptors bound…”
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Formyl peptide receptor-mediated ERK1/2 activation occurs through Gi and is not dependent on β-arrestin1/2 by Gripentrog, Jeannie M., Miettinen, Heini M.

“…Formyl peptide receptor (FPR) and C5a receptor (C5aR) are chemoattractant G protein-coupled receptors (GPCRs) involved in the innate immune response against…”
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