Search Results - "Grinyo, J.M."

Novel Once‐Daily Extended‐Release Tacrolimus (LCPT) Versus Twice‐Daily Tacrolimus in De Novo Kidney Transplants: One‐Year Results of Phase III, Double‐Blind, Randomized Trial by Budde, K., Bunnapradist, S., Grinyo, J. M., Ciechanowski, K., Denny, J. E., Silva, H. T., Rostaing, L.

“…This Phase III randomized trial examined efficacy and safety of a novel once‐daily extended‐release tacrolimus formulation (LCP‐Tacro [LCPT]) versus…”
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Three‐Year Outcomes From BENEFIT‐EXT: A Phase III Study of Belatacept Versus Cyclosporine in Recipients of Extended Criteria Donor Kidneys by Medina Pestana, J. O., Grinyo, J. M., Vanrenterghem, Y., Becker, T., Campistol, J. M., Florman, S., Garcia, V. D., Kamar, N., Lang, P., Manfro, R. C., Massari, P., Rial, M. D. C., Schnitzler, M. A., Vitko, S., Duan, T., Block, A., Harler, M. B., Durrbach, A.

“…Recipients of extended‐criteria donor (ECD) kidneys have poorer long‐term outcomes compared to standard‐criteria donor kidney recipients. We report 3‐year…”
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Low serum mannose-binding lectin levels are associated with inflammation and apoptosis in early surveillance allograft biopsies by Ibernon, M, Moreso, F, O'Valle, F, Grinyo, J.M, Moral, R.G, Seron, D

“…Abstract Introduction Mannose-binding lectin (MBL) is a protein of the innate immune system that participates in host defense and the tissue injury/repair…”
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Bone Marrow Transplantation Induces Normoglycemia in a Type 2 Diabetes Mellitus Murine Model by Flaquer, M, Franquesa, M, Barquinero, J, Lloberas, N, Gutiérrez, C, Torras, J, Grinyo, J.M, Cruzado, J.M

“…Abstract Objective To study the cellular mechanisms involved in the regression of diabetic nephropathy, bone marrow-derived cells must be identified. The aim…”
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Long‐Term Outcomes in Belatacept‐ Versus Cyclosporine‐Treated Recipients of Extended Criteria Donor Kidneys: Final Results From BENEFIT‐EXT, a Phase III Randomized Study by Durrbach, A., Pestana, J. M., Florman, S., Carmen Rial, M., Rostaing, L., Kuypers, D., Matas, A., Wekerle, T., Polinsky, M., Meier‐Kriesche, H. U., Munier, S., Grinyó, J. M.

“…In the Belatacept Evaluation of Nephroprotection and Efficacy as First‐Line Immunosuppression Trial–Extended Criteria Donors (BENEFIT‐EXT), extended criteria…”
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Pharmacokinetics and Pharmacodynamics in Renal Transplant Recipients Under Treatment With Cyclosporine and Myfortic by Brunet, M, Crespo, M, Millán, O, Serón, D, Torregrosa, V, Jiménez, O, Moreso, F, Martorell, J, Grinyo, J.M, Oppenheimer, F

“…Abstract Introduction Efficacious prophylaxis of acute rejection episodes (ARE) requires adequate exposure to each component of the immunosuppressive treatment…”
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Early Sirolimus Use With Cyclosporine Elimination Does Not Induce Progressive Proteinuria by Ruiz, J.C, Campistol, J.M, Sanchez-Fructuoso, A, Mota, A, Grinyo, J.M, Paul, J, Castro-Henriques, A, Reimao-Pinto, J, Garcia, J, Morales, J.M, Granados, E, Arias, M

“…Abstract Proteinuria has been reported in several papers after conversion from calcineurin inhibitors to Sirolimus (SRL), but this complication has not been…”
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The MEST score provides earlier risk prediction in lgA nephropathy by Barbour, Sean J, Espino-Hernandez, Gabriela, Reich, Heather N, Coppo, Rosanna, Roberts, Ian S D, Feehally, John, Herzenberg, Andrew M, Cattran, Daniel C

“…The Oxford Classification of IgA nephropathy (IgAN) includes the following four histologic components: mesangial (M) and endocapillary (E) hypercellularity,…”
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HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatory-induced mechanisms by Herrero-Fresneda, I., Torras, J., Franquesa, M., Vidal, A., Cruzado, J.M., Lloberas, N., Fillat, C., Grinyó, J.M.

“…Inflammatory processes and tissue scarring are characteristic features of chronic allograft nephropathy. Hepatocyte growth factor (HGF) has beneficial effects…”
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Revisiting Double Kidney Transplantation: Two Kidneys Provide Better Graft Survival Than One by Cruzado, J.M, Fernandez, L, Riera, L, Bestard, O, Carrera, M, Torras, J, Vernet, S. Gil, Melilli, E, Ngango, L, Grinyó, J.M

“…Abstract Double kidney transplantation is an accepted strategy to increase the donor pool. Regarding older donor kidneys, protocols for deciding to perform a…”
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Sotrastaurin, a Novel Small Molecule Inhibiting Protein Kinase C: First Clinical Results in Renal‐Transplant Recipients by Budde, K., Sommerer, C., Becker, T., Asderakis, A., Pietruck, F., Grinyo, J. M., Rigotti, P., Dantal, J., Ng, J., Barten, M. J., Weber, M.

“…Sotrastaurin, a novel protein‐kinase‐C inhibitor, blocks early T‐cell activation. In this 12‐month, Phase II study, de novo renal‐transplant patients were…”
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Contribution of Anemia and Hypertension to Left Ventricular Hypertrophy During the Initial 2 Years After Renal Transplantation by Ibernon, M, Moreso, F, Ruiz-Majoral, A, Sarrias, X, Sarrias, M, Grinyó, J.M, Serón, D

“…Abstract Background Cardiovascular disease is the main cause of mortality after renal transplantation. Left ventricular hypertrophy (LVH) is considered to be…”
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Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients by Arbiol-Roca, A., Padró-Miquel, A., Hueso, M., Navarro, E., Alía-Ramos, P., González-Álvarez, M.T., Rama, I., Torras, J., Grinyó, J.M., Cruzado, J.M., Lloberas, N.

“…A long non-coding RNA called ANRIL located on chromosome 9p21.3 has been identified as a novel genetic factor associated with cardiovascular disease…”
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De Novo Use of Everolimus With Elimination or Minimization of Cyclosporine in Renal Transplant Recipients by Novoa, P.A, Grinyó, J.M, Ramos, F.J.P, Errasti, P, Franco, A, Aldana, G, Pefaur, J, Marti-Cuadros, A.M, Otero, A.B, Saval, N, Oppenheimer, F

“…Abstract Background The purpose of two similarly designed multicenter, prospective, parallel-group, open-label studies was to evaluate early cyclosporine (CsA)…”
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Tubular Epithelial Cells Transfected With hHGF Counteracts Monocyte Chemotactic Protein-1 Up-regulation After Hypoxia/Reoxygenation Insult by Franquesa, M, Riera, M, Herrero-Fresneda, I, Sola, A, Hotter, G, Lloberas, N, Cruzado, J.M, Torras, J, Grinyó, J.M

“…Abstract Acute kidney injury (AKI) which is mainly produced by nephrotoxic or ischemic insults is correlated with a high mortality and morbidity. Proximal…”
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In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection by Ripoll, E, Pluvinet, R, Torras, J, Olivar, R, Vidal, A, Franquesa, M, Cassis, L, Cruzado, J M, Bestard, O, Grinyó, J M, Aran, J M, Herrero-Fresneda, I

“…The humoral branch of the immune response has an important role in acute and chronic allograft dysfunction. The CD40/CD40L costimulatory pathway is crucial in…”
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Similar Lipid Profile But Improved Long-Term Outcomes With Sirolimus After Cyclosporine Withdrawal Compared to Sirolimus With Continuous Cyclosporine by Morales, J.M, Hartmann, A, Walker, R, Arns, W, Senatorski, G, Grinyó, J.M, Shoker, A, Wilczek, H, Jamieson, N.V, Lelong, M, Brault, Y, Burke, J.T, Scarola, J.A

“…Abstract Renal transplant recipients show an increased risk of cardiovascular disease compared with a nontransplant population. Herein we have shown an…”
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Donor Structural and Functional Parameters Are Independent Predictors of Renal Function at 3 Months by Ibernon, M, González-Segura, C, Moreso, F, Gomà, M, Serón, D, Fulladosa, X, Torras, J, Garcia-Huete, L, Gil-Vernet, S, Cruzado, J.M, Carrera, M, Duarte, V, Grinyó, J.M

“…Abstract Introduction Epidemiological studies have shown that demographic, clinical, and histological donor characteristics influence renal function after…”
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PUK10 - ANALYZING HEALTH-ECONOMIC EFFECTS OF A RENAL PRE-TRANSPLANT PATIENT-STRATIFICATION TOOL AT AN EARLY STAGE OF PRODUCT DEVELOPMENT by Weber, S.A., Pietzsch, M., Grinyo Boira, J.M., Preyer, R., Stein, M., Reinke, P., Volk, H.

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Role of ischemia-reperfusion injury in the development of chronic renal allograft damage by Grinyo, J.M.

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