Search Results - "Grinyo, J."

Calcineurin Inhibitor Minimization in the Symphony Study: Observational Results 3 Years after Transplantation by Ekberg, H., Bernasconi, C., Tedesco‐Silva, H., Vítko, S., Hugo, C., Demirbas, A., Acevedo, R. Reyes, Grinyó, J., Frei, U., Vanrenterghem, Y., Daloze, P., Halloran, P.

“…The Symphony study showed that at 1 year posttransplant, a regimen based on daclizumab induction, 2 g mycophenolate mofetil (MMF), low‐dose tacrolimus and…”
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A Phase III Study of Belatacept Versus Cyclosporine in Kidney Transplants from Extended Criteria Donors (BENEFIT‐EXT Study) by Durrbach, A., Pestana, J. M., Pearson, T., Vincenti, F., Garcia, V. D., Campistol, J., Del Carmen Rial, M., Florman, S., Block, A., Di Russo, G., Xing, J., Garg, P., Grinyó, J.

“…Recipients of extended criteria donor (ECD) kidneys are at increased risk for graft dysfunction/loss, and may benefit from immunosuppression that avoids…”
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Novel Once‐Daily Extended‐Release Tacrolimus (LCPT) Versus Twice‐Daily Tacrolimus in De Novo Kidney Transplants: One‐Year Results of Phase III, Double‐Blind, Randomized Trial by Budde, K., Bunnapradist, S., Grinyo, J. M., Ciechanowski, K., Denny, J. E., Silva, H. T., Rostaing, L.

“…This Phase III randomized trial examined efficacy and safety of a novel once‐daily extended‐release tacrolimus formulation (LCP‐Tacro [LCPT]) versus…”
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Three‐Year Outcomes From BENEFIT‐EXT: A Phase III Study of Belatacept Versus Cyclosporine in Recipients of Extended Criteria Donor Kidneys by Medina Pestana, J. O., Grinyo, J. M., Vanrenterghem, Y., Becker, T., Campistol, J. M., Florman, S., Garcia, V. D., Kamar, N., Lang, P., Manfro, R. C., Massari, P., Rial, M. D. C., Schnitzler, M. A., Vitko, S., Duan, T., Block, A., Harler, M. B., Durrbach, A.

“…Recipients of extended‐criteria donor (ECD) kidneys have poorer long‐term outcomes compared to standard‐criteria donor kidney recipients. We report 3‐year…”
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Detrimental effects of ocean acidification on the economically important Mediterranean red coral (Corallium rubrum) by Bramanti, L., Movilla, J., Guron, M., Calvo, E., Gori, A., Dominguez-Carrió, C., Grinyó, J., Lopez-Sanz, A., Martinez-Quintana, A., Pelejero, C., Ziveri, P., Rossi, S.

“…The mean predicted decrease of 0.3–0.4 pH units in the global surface ocean by the end of the century has prompted urgent research to assess the potential…”
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A Randomized, Multicenter Study of Steroid Avoidance, Early Steroid Withdrawal or Standard Steroid Therapy in Kidney Transplant Recipients by Vincenti, F., Schena, F. P., Paraskevas, S., Hauser, I. A., Walker, R. G., Grinyo, J.

“…In a randomized, open‐label, multicenter study, de novo renal transplant patients received no steroids (n = 112), steroids to day 7 (n = 115), or standard…”
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Distribution patterns and demographic trends of demosponges at the Menorca Channel (Northwestern Mediterranean Sea) by Santín, A., Grinyó, J., Ambroso, S., Uriz, M.J., Dominguez-Carrió, C., Gili, J.M.

“…•The geographical, bathymetrical and size distribution of 11 Mediterranean sponges was evaluated.•A clear zonation pattern between species was…”
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Sotrastaurin, a Novel Small Molecule Inhibiting Protein Kinase C: First Clinical Results in Renal‐Transplant Recipients by Budde, K., Sommerer, C., Becker, T., Asderakis, A., Pietruck, F., Grinyo, J. M., Rigotti, P., Dantal, J., Ng, J., Barten, M. J., Weber, M.

“…Sotrastaurin, a novel protein‐kinase‐C inhibitor, blocks early T‐cell activation. In this 12‐month, Phase II study, de novo renal‐transplant patients were…”
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Sirolimus in association with mycophenolate mofetil induction for the prevention of acute graft rejection in renal allograft recipients by KREIS, H, CISTERNE, J.-M, BERTHOUX, F.-C, BRATTSTRÖM, C, LEBRANCHU, Y, VIALTEL, P, LAND, W, WRAMNER, L, SQUIFFLET, J.-P, ABRAMOWICZ, D, CAMPISTOL, J. M, MORALES, J.-M, GRINYO, J.-M, MOURAD, G

“…A previous trial in renal transplantation comparing sirolimus (rapamycin) to cyclosporine (CsA) in a triple-drug therapy regimen with azathioprine and…”
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An Integrated Safety Profile Analysis of Belatacept in Kidney Transplant Recipients by GRINYO, Josep, CHARPENTIER, Bernard, LARSEN, Christian P, MEDINA PESTANA, José, VANRENTERGHEM, Yves, VINCENTI, Flavio, REYES-ACEVEDO, Rafael, APANOVITCH, Anne Marie, GUJRATHI, Sheila, AGARWAL, Mamta, THOMAS, Dolca

“…Belatacept is associated with better renal function and an improved cardiovascular/metabolic risk profile versus cyclosporine in kidney transplant recipients…”
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Optimizing Cadaveric Organ Procurement: the Catalan and Spanish Experience by Miranda, B., Vilardell, J., Grinyó, J. M.

“…The need to face the increasing gap between the supply and the demand of transplants has led to the development of a permanent network of trained medical staff…”
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Pretransplant Immediately Early‐1‐Specific T Cell Responses Provide Protection for CMV Infection After Kidney Transplantation by Bestard, O., Lucia, M., Crespo, E., Van Liempt, B., Palacio, D., Melilli, E., Torras, J., Llaudó, I., Cerezo, G., Taco, O., Gil‐Vernet, S., Grinyó, J. M., Cruzado, J. M.

“…Cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although cytotoxic CMV‐specific T cells play a crucial role…”
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Human Adipose Tissue‐Derived Mesenchymal Stem Cells Abrogate Plasmablast Formation and Induce Regulatory B Cells Independently of T Helper Cells by Franquesa, M., Mensah, F. K., Huizinga, R., Strini, T., Boon, L., Lombardo, E., DelaRosa, O., Laman, J. D., Grinyó, J. M., Weimar, W., Betjes, M. G. H., Baan, C. C., Hoogduijn, M. J.

“…Mesenchymal or stromal stem cells (MSC) interact with cells of the immune system in multiple ways. Modulation of the immune system by MSC is believed to be a…”
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The ORION Study: Comparison of Two Sirolimus‐Based Regimens versus Tacrolimus and Mycophenolate Mofetil in Renal Allograft Recipients by Flechner, S. M., Glyda, M., Cockfield, S., Grinyó, J., Legendre, Ch, Russ, G., Steinberg, S., Wissing, K. M., Tai, S. S.

“…Safety and efficacy of two sirolimus (SRL)‐based regimens were compared with tacrolimus (TAC) and mycophenolate mofetil (MMF). Renal transplantation recipients…”
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Hepatitis C Virus Infection and de Novo Glomerular Lesions in Renal Allografts by Cruzado, Josep M., Carrera, Marta, Torras, Joan, Grinyó, Josep M.

“…In the present study we examine whether hepatitis C virus (HCV) infection status influences glomerular pathologic findings in renal allografts and its effect…”
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Long‐Term Belatacept Exposure Maintains Efficacy and Safety at 5 Years: Results From the Long‐Term Extension of the BENEFIT Study by Rostaing, L., Vincenti, F., Grinyó, J., Rice, K. M., Bresnahan, B., Steinberg, S., Gang, S., Gaite, L. E., Moal, M.‐C., Mondragón‐Ramirez, G. A., Kothari, J., Pupim, L., Larsen, C. P.

“…The Belatacept Evaluation of Nephroprotection and Efficacy as First‐line Immunosuppression Trial randomized patients receiving a living or standard criteria…”
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Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation by VINCENTI, F, RAMOS, E, NAVARRO, M, NASHAN, B, BRATTSTROM, C, CHO, S, EKBERG, H, GRINYO, J, JOHNSON, R, KUYPERS, D, STUART, F, KHANNA, A

“…The adoption of calcineurin inhibitors (CNI) as the mainstay of immunosuppression has resuited in a significant decrease of acute rejection and improvement of…”
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Long‐Term Outcomes in Belatacept‐ Versus Cyclosporine‐Treated Recipients of Extended Criteria Donor Kidneys: Final Results From BENEFIT‐EXT, a Phase III Randomized Study by Durrbach, A., Pestana, J. M., Florman, S., Carmen Rial, M., Rostaing, L., Kuypers, D., Matas, A., Wekerle, T., Polinsky, M., Meier‐Kriesche, H. U., Munier, S., Grinyó, J. M.

“…In the Belatacept Evaluation of Nephroprotection and Efficacy as First‐Line Immunosuppression Trial–Extended Criteria Donors (BENEFIT‐EXT), extended criteria…”
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Low serum mannose-binding lectin levels are associated with inflammation and apoptosis in early surveillance allograft biopsies by Ibernon, M, Moreso, F, O'Valle, F, Grinyo, J.M, Moral, R.G, Seron, D

“…Abstract Introduction Mannose-binding lectin (MBL) is a protein of the innate immune system that participates in host defense and the tissue injury/repair…”
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Protocol renal allograft biopsies and the design of clinical trials aimed to prevent or treat chronic allograft nephropathy by SERON, D, MORESO, F, GRINYO, J. M, RAMON, J. M, HUESO, M, CONDOM, E, FULLADOSA, X, BOVER, J, GIL-VERNET, S, CASTELAO, A. M, ALSINA, J

“…The minimum sample size to perform a clinical trial aimed to modify the natural history of chronic allograft nephropathy (CAN) is very large. Since the…”
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