Search Results - "Grinstaff Mark, W"

Polymer–drug conjugate therapeutics: advances, insights and prospects by Ekladious, Iriny, Colson, Yolonda L., Grinstaff, Mark W.

“…Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several conjugates successfully translated into clinical practice. The…”
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Single-molecule protein sensing in a nanopore: a tutorial by Varongchayakul, Nitinun, Song, Jiaxi, Meller, Amit, Grinstaff, Mark W

“…Proteins are the structural elements and machinery of cells responsible for a functioning biological architecture and homeostasis. Advances in nanotechnology…”
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On-Demand Dissolution of Chemically Cross-Linked Hydrogels by Konieczynska, Marlena D, Grinstaff, Mark W

“…The formation and subsequent on-demand dissolution of chemically cross-linked hydrogels is of keen interest to chemists, engineers, and clinicians. In this…”
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Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies by Mahvi, David A., Liu, Rong, Grinstaff, Mark W., Colson, Yolonda L., Raut, Chandrajit P.

“…Locoregional recurrence negatively impacts both long‐term survival and quality of life for several malignancies. For appropriate‐risk patients with an…”
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Recent Advances in Glycerol Polymers: Chemistry and Biomedical Applications by Zhang, Heng, Grinstaff, Mark W.

“…Glycerol polymers are attracting increased attention due to the diversity of polymer compositions and architectures available. This article provides a brief…”
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Biologically Responsive Polymeric Nanoparticles for Drug Delivery by Colson, Yolonda L., Grinstaff, Mark W.

“…Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this…”
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Biocompatible and Bioactive Surface Modifications for Prolonged In Vivo Efficacy by Meyers, Steven R, Grinstaff, Mark W

“…A comprehensive examination of the bioactive surface modification and biocompatibility for prolonged in vivo efficacy is presented, focusing on numerous…”
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Sustainable polycarbonate adhesives for dry and aqueous conditions with thermoresponsive properties by Beharaj, Anjeza, McCaslin, Ethan Z., Blessing, William A., Grinstaff, Mark W.

“…Pressure sensitive adhesives are ubiquitous in commodity products such as tapes, bandages, labels, packaging, and insulation. With single use plastics…”
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On-Demand Dissolution of a Dendritic Hydrogel-based Dressing for Second-Degree Burn Wounds through Thiol-Thioester Exchange Reaction by Konieczynska, Marlena D., Villa-Camacho, Juan C., Ghobril, Cynthia, Perez-Viloria, Miguel, Tevis, Kristie M., Blessing, William A., Nazarian, Ara, Rodriguez, Edward K., Grinstaff, Mark W.

“…An adhesive yet easily removable burn wound dressing represents a breakthrough in second‐degree burn wound care. Current second‐degree burn wound dressings…”
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Superhydrophobic Materials for Tunable Drug Release: Using Displacement of Air To Control Delivery Rates by Yohe, Stefan T, Colson, Yolonda L, Grinstaff, Mark W

“…We have prepared 3D superhydrophobic materials from biocompatible building blocks, where air acts as a barrier component in a porous electrospun mesh to…”
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Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration by McDermott, Anna M, Herberg, Samuel, Mason, Devon E, Collins, Joseph M, Pearson, Hope B, Dawahare, James H, Tang, Rui, Patwa, Amit N, Grinstaff, Mark W, Kelly, Daniel J, Alsberg, Eben, Boerckel, Joel D

“…Large bone defects cannot form a callus and exhibit high complication rates even with the best treatment strategies available. Tissue engineering approaches…”
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Single-Molecule Discrimination of Labeled DNAs and Polypeptides Using Photoluminescent-Free TiO2 Nanopores by Wang, Rui, Gilboa, Tal, Song, Jiaxi, Huttner, Diana, Grinstaff, Mark W., Meller, Amit

“…Multicolor fluorescence substantially expands the sensing capabilities of nanopores by complementing or substituting the resistive pulsing signals. However, to…”
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Mimicking the tumor microenvironment to regulate macrophage phenotype and assessing chemotherapeutic efficacy in embedded cancer cell/macrophage spheroid models by Tevis, Kristie M., Cecchi, Ryan J., Colson, Yolonda L., Grinstaff, Mark W.

“…[Display omitted] Tumor associated macrophages (TAMs) are critical stromal components intimately involved with the progression, invasion, and metastasis of…”
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Synthesis of bioactive (1→6)-β-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages by Xiao, Ruiqing, Zeng, Jialiu, Bressler, Eric M., Lu, Wei, Grinstaff, Mark W.

“…β-Glucans are of significant interest due to their potent antitumor and immunomodulatory activities. Nevertheless, the difficulty in purification, structural…”
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Expansile Nanoparticles: Synthesis, Characterization, and in Vivo Efficacy of an Acid-Responsive Polymeric Drug Delivery System by Griset, Aaron P, Walpole, Joseph, Liu, Rong, Gaffey, Ann, Colson, Yolonda L, Grinstaff, Mark W

“…Nanoparticles are finding increased uses in drug delivery applications as a means to increase treatment efficacy and improve patient care. Here, we report…”
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Synthetic Biomaterials from Metabolically Derived Synthons by Ricapito, Nicole G, Ghobril, Cynthia, Zhang, Heng, Grinstaff, Mark W, Putnam, David

“…The utility of metabolic synthons as the building blocks for new biomaterials is based on the early application and success of hydroxy acid based polyesters as…”
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Pancreatic Adenocarcinoma: Unconventional Approaches for an Unconventional Disease by Gromisch, Christopher, Qadan, Motaz, Machado, Mariana Albuquerque, Liu, Kebin, Colson, Yolonda, Grinstaff, Mark W

“…This review highlights current treatments, limitations, and pitfalls in the management of pancreatic cancer and discusses current research in novel targets and…”
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Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease by Zeng, Jialiu, Acin-Perez, Rebeca, Assali, Essam A., Martin, Andrew, Brownstein, Alexandra J., Petcherski, Anton, Fernández-del-Rio, Lucía, Xiao, Ruiqing, Lo, Chih Hung, Shum, Michaël, Liesa, Marc, Han, Xue, Shirihai, Orian S., Grinstaff, Mark W.

“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world. High levels of free fatty acids in the liver impair hepatic lysosomal…”
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Functional lipids and lipoplexes for improved gene delivery by Zhang, Xiao-Xiang, McIntosh, Thomas J., Grinstaff, Mark W.

“…Cationic lipids are the most common non-viral vectors used in gene delivery with a few currently being investigated in clinical trials. However, like most…”
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Self-assembly of a 5-fluorouracil-dipeptide hydrogel by Sun, Yuan, Kaplan, Jonah A, Shieh, Aileen, Sun, Hui-Lung, Croce, Carlo M, Grinstaff, Mark W, Parquette, Jon R

“…The self-assembly of 5-fluorouracil dilysine conjugates into self-supporting hydrogels, comprised of entangled nanofibers or rigid nanotubes with diameters of…”
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