Search Results - "Grinnen, Karen L"

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    Profound impairment of adaptive immune responses by alkylating chemotherapy

    Profound impairment of adaptive immune responses by alkylating chemotherapy by Litterman, Adam J, Zellmer, David M, Grinnen, Karen L, Hunt, Matthew A, Dudek, Arkadiusz Z, Salazar, Andres M, Ohlfest, John R

    Published in The Journal of immunology (1950) (15-06-2013)
    “…Overall, cancer vaccines have had a record of failure as an adjuvant therapy for malignancies that are treated with alkylating chemotherapy, and the…”
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  2. 2
    Abstract B23: DNA damage response in responder lymphocytes reduces vaccine efficacy following alkylating chemotherapy

    Abstract B23: DNA damage response in responder lymphocytes reduces vaccine efficacy following alkylating chemotherapy by Litterman, Adam J., Zellmer, David M., Grinnen, Karen L., Dudek, Arkadiusz Z., Largaespada, David A., Ohlfest, John R.

    Published in Cancer research (Chicago, Ill.) (01-01-2013)
    “…Abstract The effect of alkylating chemotherapy on cancer vaccines is controversial, with numerous reports of immune stimulation via Treg depletion following…”
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