Search Results - "Grinde, Ellinor"

Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic, and dopamine receptor dimerization: the oligomer number puzzle by Herrick-Davis, Katharine, Grinde, Ellinor, Cowan, Ann, Mazurkiewicz, Joseph E

“…The issue of G protein-coupled receptor (GPCR) oligomer status has not been resolved. Although many studies have provided evidence in favor of…”
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Beta2-adrenergic receptor homodimers: Role of transmembrane domain 1 and helix 8 in dimerization and cell surface expression by Parmar, Vikas K., Grinde, Ellinor, Mazurkiewicz, Joseph E., Herrick-Davis, Katharine

“…Even though there are hundreds of reports in the published literature supporting the hypothesis that G protein-coupled receptors (GPCR) form and function as…”
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Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors by Herrick-Davis, K, Grinde, E, Teitler, M

“…Clozapine is the prototype atypical antipsychotic drug, producing little or no extrapyramidal side effects, while improving negative symptoms of psychosis…”
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Serotonin 5-HT2C Receptor Homodimer Biogenesis in the Endoplasmic Reticulum by Herrick-Davis, Katharine, Weaver, Barbara A., Grinde, Ellinor, Mazurkiewicz, Joseph E.

“…Dimerization is a common property of G-protein-coupled receptors (GPCR). While the formation of GPCR dimers/oligomers has been reported to play important roles…”
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Inhibition of Serotonin 5-Hydroxytryptamine2C Receptor Function through Heterodimerization by Herrick-Davis, Katharine, Grinde, Ellinor, Harrigan, Timothy J., Mazurkiewicz, Joseph E.

“…Although dimerization appears to be a common property of G-protein-coupled receptors (GPCRs), it remains unclear whether a GPCR dimer binds one or two…”
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Oligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramers by Herrick-Davis, Katharine, Grinde, Ellinor, Lindsley, Tara, Cowan, Ann, Mazurkiewicz, Joseph E

“…Fluorescence correlation spectroscopy (FCS) and photon counting histogram (PCH) are techniques with single molecule sensitivity that are well suited for…”
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Native serotonin 5-HT2C receptors are expressed as homodimers on the apical surface of choroid plexus epithelial cells by Herrick-Davis, Katharine, Grinde, Ellinor, Lindsley, Tara, Teitler, Milt, Mancia, Filippo, Cowan, Ann, Mazurkiewicz, Joseph E

“…G protein-coupled receptors (GPCRs) are a prominent class of plasma membrane proteins that regulate physiologic responses to a wide variety of stimuli and…”
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Characterization of a new mRNA species from the human histamine N-methyltransferase gene by Barnes, William G, Grinde, Ellinor, Crawford, Dana R, Herrick-Davis, Katharine, Hough, Lindsay B

“…Histamine N-methyltransferase (HNMT), a cytosolic histamine-metabolizing enzyme, is the only known product of the 50-kb human HNMT. Here, a detailed…”
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Beta 2 -adrenergic receptor homodimers: Role of transmembrane domain 1 and helix 8 in dimerization and cell surface expression by Parmar, Vikas K, Grinde, Ellinor, Mazurkiewicz, Joseph E, Herrick-Davis, Katharine

“…Even though there are hundreds of reports in the published literature supporting the hypothesis that G protein-coupled receptors (GPCR) form and function as…”
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Serotonin 5-HT₂C Receptor Homodimer Biogenesis in the Endoplasmic Reticulum: REAL-TIME VISUALIZATION WITH CONFOCAL FLUORESCENCE RESONANCE ENERGY TRANSFER by Herrick-Davis, Katharine, Weaver, Barbara A, Grinde, Ellinor, Mazurkiewicz, Joseph E

“…Dimerization is a common property of G-protein-coupled receptors (GPCR). While the formation of GPCR dimers/oligomers has been reported to play important roles…”
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Serotonin 5‐HT2C receptor homodimers identified by Fluorescence Correlation Spectroscopy by Herrick-Davis, Katharine, Grinde, Ellinor, Mazurkiewicz, Joseph E

“…Abstract only Fluorescence correlation spectroscopy (FCS) and photon counting histogram (PCH) were applied to determine diffusion rate and oligomeric size of…”
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Agonist high and low affinity state ratios predict drug intrinsic activity and a revised Ternary complex mechanism at serotonin 5-HT2A and 5-HT2C receptors by Egan, Christina, Grinde, Ellinor, Dupre, Ann, Roth, Bryan L., Hake, Michael, Teitler, Milt, Herrick-Davis, Katharine

“…The ternary complex model as applied to G‐protein coupled receptors (GPCR) predicts that an agonist binds with low affinity (KL) to the free receptor (R),…”
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Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein by Herrick-Davis, Katharine, Grinde, Ellinor, Harrigan, Timothy J, Mazurkiewicz, Joseph E

“…Although dimerization appears to be a common property of G-protein-coupled receptors (GPCRs), it remains unclear whether a GPCR dimer binds one or two…”
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Biochemical and Biophysical Characterization of Serotonin 5-HT2C Receptor Homodimers on the Plasma Membrane of Living Cells by Herrick-Davis, Katharine, Grinde, Ellinor, Mazurkiewicz, Joseph E

“…While many studies have provided evidence of homodimerization and heterodimerization of G-protein-coupled receptors (GPCRs), few studies have used fluorescence…”
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Oligomer Size of the Serotonin 5-Hydroxytryptamine 2C (5-HT2C) Receptor Revealed by Fluorescence Correlation Spectroscopy with Photon Counting Histogram Analysis by Herrick-Davis, Katharine, Grinde, Ellinor, Lindsley, Tara, Cowan, Ann, Mazurkiewicz, Joseph E.

“…Fluorescence correlation spectroscopy (FCS) and photon counting histogram (PCH) are techniques with single molecule sensitivity that are well suited for…”
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Serotonin 5-HT2C receptor homodimerization is not regulated by agonist or inverse agonist treatment by HERRICK-DAVIS, Katharine, GRINDE, Ellinor, WEAVER, Barbara A

“…Serotonin 5-HT 2C receptors represent targets for therapeutics aimed at treating anxiety, depression, schizophrenia, and obesity. Previously, we demonstrated…”
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Serotonin 5‐HT2C Receptor RNA Editing Alters Receptor Basal Activity by Herrick‐Davis, Katharine, Grinde, Ellinor, Niswender, Colleen M.

“…: Rat and human serotonin 5‐HT2C receptor isoforms were evaluated for agonist‐independent activation of inositol phosphate production in COS‐7 cells. The…”
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Serotonin 5-HT(2C) receptor homodimerization is not regulated by agonist or inverse agonist treatment by Herrick-Davis, Katharine, Grinde, Ellinor, Weaver, Barbara A

“…Serotonin 5-HT(2C) receptors represent targets for therapeutics aimed at treating anxiety, depression, schizophrenia, and obesity. Previously, we demonstrated…”
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Serotonin 5-HT 2C receptor homodimerization is not regulated by agonist or inverse agonist treatment by Herrick-Davis, Katharine, Grinde, Ellinor, Weaver, Barbara A.

“…Serotonin 5-HT 2C receptors represent targets for therapeutics aimed at treating anxiety, depression, schizophrenia, and obesity. Previously, we demonstrated…”
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Serotonin 5-HT sub(2C) Receptor Homodimer Biogenesis in the Endoplasmic Reticulum: REAL-TIME VISUALIZATION WITH CONFOCAL FLUORESCENCE RESONANCE ENERGY TRANSFER by Herrick-Davis, Katharine, Weaver, Barbara A, Grinde, Ellinor, Mazurkiewicz, Joseph E

“…Dimerization is a common property of G-protein-coupled receptors (GPCR). While the formation of GPCR dimers/oligomers has been reported to play important roles…”
Get full text