Search Results - "Grimm, Leander"
-
1
Functional Disorders of Constipation: Paradoxical Puborectalis Contraction and Increased Perineal Descent
Published in Clinics in colon and rectal surgery (01-02-2017)“…Paradoxical puborectalis contraction (PPC) and increased perineal descent (IPD) are subclasses of obstructive defecation. Often these conditions coexist, which…”
Get full text
Journal Article -
2
Changing the Way We Manage Rectal Cancer-Standardizing TME from Open to Robotic (Including Laparoscopic)
Published in Clinics in colon and rectal surgery (01-03-2015)“…Standardizing total mesorectal excision (TME) has been a topic of interest since 1979 when Professor Richard J. Heald first described TME and a new approach to…”
Get full text
Journal Article -
3
Modern rectal cancer surgery—Total mesorectal excision—The standard of care
Published in Seminars in colon and rectal surgery (01-09-2013)“…Abstract The literature has repeatedly shown the superiority of total mesorectal excision (TME) for rectal cancer in reducing the incidence of local recurrence…”
Get full text
Journal Article -
4
-
5
Endoscopic technique for closure of enterocutaneous fistulas
Published in Surgical endoscopy (01-10-2019)“…Background and objectives Endoscopic over the scope clip (OTSC) closure represents a new technique for endoscopic management of enteric bleeding and tissue…”
Get full text
Journal Article -
6
The Diagnostic and Therapeutic Challenge of Anal Intraepithelial Neoplasia
Published in Current gastroenterology reports (01-08-2018)“…Purpose of Review No single modality of care serves as the defined best practice for the treatment of anal intraepithelial neoplasia (AIN). This review aims to…”
Get full text
Journal Article -
7
The clinical and molecular characteristics of patients with personal or family history of gastrointestinal malignancies/polyposis and checkpoint kinase 2 (CHEK2) mutations
Published in Journal of clinical oncology (20-01-2021)“…Abstract only 44 Background: Checkpoint Kinase 2 (CHEK 2) encodes the protein CHK2, a serine/threonine kinase involved in pathways that conduct DNA repair as…”
Get full text
Journal Article -
8
Germline testing of patients with personal history of colorectal polyposis by cancer genetics counseling services
Published in Journal of clinical oncology (20-01-2021)“…Abstract only 47 Background: National Comprehensive Cancer Network (NCCN) guidelines recommend that individuals with >10 adenomatous polyps, ≥2 hamartomatous…”
Get full text
Journal Article -
9
The clinical and molecular characteristics of patients with personal history of colorectal cancer evaluated by cancer genetics counseling services
Published in Journal of clinical oncology (20-01-2021)“…Abstract only 46 Background: Genetic susceptibility to colorectal cancer (CRC) include well-defined hereditary syndromes such as Lynch Syndrome, Familial…”
Get full text
Journal Article -
10
The effects of neoadjuvant chemoradiation on exosomal markers (CD63 and CD9) expression in patients with locally advanced rectal adenocarcinoma
Published in Journal of clinical oncology (20-01-2021)“…Abstract only 101 Background: Exosomes mediate intercellular communications and have pivotal roles in cancer development. CD63 and CD9 are widely accepted…”
Get full text
Journal Article -
11
Exosomal marker CD63 expression pattern using immunohistochemistry (IHC) in patients with rectal adenocarcinoma in comparison with left-sided colon cancer
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e16096 Background: Adenocarcinomas arising from the distal one third of the transverse colon, splenic flexure, descending colon, sigmoid colon…”
Get full text
Journal Article -
12
Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in right-sided and left-sided colon cancer
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 182 Background: Exosomes play pivotal roles in cancer progression, metastasis and chemoresistance. CD63 and CD9 are widely accepted exosomal…”
Get full text
Journal Article -
13
The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma
Published in Oncotarget (20-07-2021)“…INTRODUCTIONExosomes have pivotal roles in cancer development. The impact of neoadjuvant concurrent chemoradiation (NCCR) on exosomal markers (CD63 and CD9)…”
Get full text
Journal Article -
14
The prognostic significance of magnetic resonance imaging (MRI) following neoadjuvant concurrent chemoradiation (NCCR) in patients with locally advanced rectal adenocarcinoma (LARA)
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e15166 Background: In patients with locally advanced rectal adenocarcinoma (LARA), the response to neoadjuvant concurrent chemoradiation (NCCR)…”
Get full text
Journal Article -
15
Exosomal markers (CD63 and CD9) expression using immunohistochemistry (IHC) in patients with right-sided and left-sided colon cancer
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e15119 Background: Embryologically, the right colon (cecum, ascending colon, hepatic flexure and proximal two-thirds of the transverse colon) is…”
Get full text
Journal Article -
16
Germline pharmacogenomics of thymidylate synthase gene in patients with gastrointestinal malignancies treated with fluoropyrimidines-based chemotherapy regimens
Published in Journal of clinical oncology (01-02-2019)“…Abstract only 545 Background: Fluoropyrimidines are antimetabolites that target the S phase of the cell cycle. The active metabolite, 5-fluorodeoxyuridine…”
Get full text
Journal Article -
17
Usefulness of Restaging Pelvis Magnetic Resonance Imaging After Neoadjuvant Concurrent Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer
Published in Clinical colorectal cancer (01-12-2020)“…In patients with locally advanced rectal cancer, restaging pelvis magnetic resonance imaging (MRI) after neoadjuvant concurrent chemoradiotherapy is…”
Get full text
Journal Article -
18
Chapter 152 - Current Approaches to Complete Rectal Prolapse and Internal Intussusception
Published in Shackelford's Surgery of the Alimentary Tract (2019)“…This chapter discusses the initial evaluation and diagnostic work-up of both rectal prolapse and internal rectal intussusception. In addition, it describes the…”
Get full text
Book Chapter -
19
Current Approaches to Complete Rectal Prolapse and Internal Intussusception
Published in Shackelford's Surgery of the Alimentary Tract (01-01-2019)Get full text
Book Chapter