Search Results - "Grimes, Amanda B."
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Pediatric autoimmune myelofibrosis: Experience from a large pediatric tertiary care center
Published in Pediatric blood & cancer (01-04-2023)“…Autoimmune myelofibrosis (AIMF) is a rare disorder characterized by cytopenias and autoimmunity, with characteristic bone marrow findings that include…”
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Hydroxyurea: a new old therapy for Langerhans cell histiocytosis
Published in Blood (17-11-2016)Get full text
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Molecular Diagnosis Is Vital to the Accurate Classification and Management of Thrombotic Thrombocytopenic Purpura in Children
Published in Frontiers in immunology (11-04-2022)“…Thrombotic thrombocytopenic purpura (TTP) is a rare but potentially life-threatening hematologic disease, presenting a myriad of diagnostic and management…”
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Untargeted metabolomic profiling in a patient with glycogen storage disease Ib receiving empagliflozin treatment
Published in JIMD reports (01-07-2022)“…Glycogen storage disease type Ib (GSD‐Ib) is a rare inborn error of glycogen metabolism uniquely associated with neutropenia and neutrophil dysfunction,…”
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Pediatric ITP: is it different from adult ITP?
Published in Hematology (30-11-2018)“…Immune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms: childhood ITP and adult ITP. This division is based largely on the…”
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Pediatric Eosinophilia: A Review and Multiyear Investigation into Etiologies
Published in The Journal of pediatrics (01-02-2023)“…To identify the etiology of peripheral eosinophilia in a large pediatric population and to develop a diagnostic algorithm to help guide diagnosis and…”
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Pediatric refractory immune thrombocytopenia: A systematic review
Published in Pediatric blood & cancer (01-03-2023)“…Pediatric immune thrombocytopenia (ITP) is an acquired disorder associated with autoimmune destruction and impairment of platelet production in children. Some…”
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Refractory autoimmune cytopenias in pediatric Evans syndrome with underlying systemic immune dysregulation
Published in European journal of haematology (01-06-2021)“…Evans syndrome is a rare but challenging disorder in children; and despite rapidly growing evidence for targetable systemic immune dysregulation driving these…”
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Racial variation in ITP prevalence and chronic disease phenotype suggests biological differences
Published in Blood (30-07-2020)Get full text
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Immunoglobulins act as predictors of chronicity in pediatric immune thrombocytopenia
Published in Blood advances (08-10-2024)Get full text
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Immune thrombocytopenia following multisystem inflammatory syndrome in children (MIS-C) - a case series
Published in Pediatric hematology and oncology (06-10-2021)“…Patients with coronavirus disease 2019 (COVID-19) from novel coronavirus (SARS-CoV-2) infection may present with immune thrombocytopenia (ITP). Multisystem…”
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Association of a positive direct antiglobulin test with chronic immune thrombocytopenia and use of second line therapies in children: A multi‐institutional review
Published in American journal of hematology (01-04-2019)“…Immune thrombocytopenia (ITP) is the most common autoimmune cytopenia in children. Approximately, 25% of patients develop chronic disease, which may be…”
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A Case of a Very Young Child With T Lymphoblastic Lymphoma With Eosinophilia and PDGFRB Translocation: A Rare Form of Myeloid/Lymphoid Neoplasm Associated With Eosinophilia and Rearrangements of PDGFRA, PDGFRB or FGFR1
Published in Clinical lymphoma, myeloma and leukemia (01-12-2020)Get full text
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Diagnostic dilemma: ALPS versus Evans syndrome
Published in Clinical immunology (Orlando, Fla.) (01-10-2017)Get full text
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Romiplostim for the Treatment of Immune Thrombocytopenia: Spotlight on Patient Acceptability and Ease of Use
Published in Patient preference and adherence (01-01-2020)“…Immune thrombocytopenia (ITP) is an immune-mediated disorder resulting in platelet destruction and subsequent thrombocytopenia. Bleeding symptoms range from…”
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Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia
Published in Blood advances (12-11-2024)“…•The allele frequency of variants in genes linked to Wnt/β-catenin signaling differed between pediatric ITP and control cohorts.•No genetic variants met…”
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What is in a name: defining pediatric refractory ITP
Published in Blood advances (08-10-2024)“…There are no agreed upon terminology to define “refractory” pediatric immune thrombocytopenia (ITP). Guidelines are therefore limited to arbitrary and outdated…”
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High Titer ANA at Pediatric ITP Presentation Associated with Progression to Systemic Lupus Erythematosus
Published in Blood (02-11-2023)“…Introduction: Immune thrombocytopenia (ITP) is a feature of systemic lupus erythematosus (SLE) in 5-20% of cases. ITP may present at the time of SLE…”
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Immunoglobulins As a Predictor of Chronicity in Pediatric Immune Thrombocytopenia
Published in Blood (02-11-2023)“…Introduction: Immune thrombocytopenia (ITP) is the most common acquired bleeding disorder in children, but predictors of chronicity at the time of diagnosis…”
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