Search Results - "Grimaldi, B"
-
1
Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells
Published in Oncogene (14-05-2015)“…REV-ERBα and REV-ERBβ nuclear receptors regulate several physiological processes, including circadian rhythm and metabolism. A previous study reported the…”
Get full text
Journal Article -
2
Antileishmanial Activity of Dimeric Flavonoids Isolated from Arrabidaea brachypoda
Published in Molecules (Basel, Switzerland) (20-12-2018)“…Leishmaniasis are diseases caused by parasites belonging to genus. The treatment with pentavalent antimonials present high toxicity. Secondary line drugs, such…”
Get full text
Journal Article -
3
Repeated exposure to aerosolized graphene oxide mediates autophagy inhibition and inflammation in a three-dimensional human airway model
Published in Materials today bio (01-03-2020)“…Hazard evaluation of engineered nanomaterials (ENMs) using real-world exposure scenario could provide better interpretation of toxicity end points for their…”
Get full text
Journal Article -
4
Synthesis of Naphthofurans by tBuOK-Catalyzed Intramolecular Anionic Cycloaddition of Unsymmetrical Bis-propargyl Ethers
Published in European journal of organic chemistry (01-11-2015)“…The tBuOK‐catalyzed intramolecular anionic cycloaddition of unsymmetrical bis‐propargyl ethers has been applied to the synthesis of naphthofurans. A systematic…”
Get full text
Journal Article -
5
Electrophilic Cyclization of N-Alkynyl-2-(organochalcogen)imidazoles: An Alternative Access to Imidazo[2,1-b]chalcogenazoles
Published in European journal of organic chemistry (01-05-2013)“…We present here a practical synthesis of multifunctional imidazo[2,1‐b]chalcogenazoles through electrophilic cyclization of…”
Get full text
Journal Article -
6
Effect of Feeding Frequency on Intake, Digestibility, Ingestive Behavior, Performance, Carcass Characteristics, and Meat Quality of Male Feedlot Lambs
Published in Agriculture (Basel) (01-08-2021)“…The study was conducted to evaluate the effects of feeding frequencies (one, two, three, and four times per day) on the performance of male feedlot lambs…”
Get full text
Journal Article -
7
Photomorphogenesis in the hypogeous fungus Tuber borchii: isolation and characterization of Tbwc-1, the homologue of the blue-light photoreceptor of Neurospora crassa
Published in Fungal genetics and biology (01-07-2004)“…Truffles form a group of plant–symbiotic Ascomycetes whose hypogeous life cycle is poorly understood. Here we present initial evidence for the influence of…”
Get full text
Journal Article -
8
Computer-Aided Drug Design Studies in Association with in vitro Antileishmanial Tests for New Chalcones
Published in Journal of the Brazilian Chemical Society (2025)“…In silico and in vitro tests can reveal promising anti-leishmania activity for natural products and their derivatives. The aim of this study was to investigate…”
Get full text
Journal Article -
9
Potassium tert-Butoxide Promoted Annulation of 2‑Alkynylphenyl Propargyl Ethers: Selective Synthesis of Benzofuran and 12H‑Benzoannulene Derivatives
Published in Journal of organic chemistry (01-11-2013)“…We present here our results on potassium tert-butoxide promoted annulation reactions of 2-alkynylphenyl propargyl ethers to give two different types of…”
Get full text
Journal Article -
10
Chromatin remodeling and circadian control: master regulator CLOCK is an enzyme
Published in Cold Spring Harbor Symposia on Quantitative Biology (2007)“…The molecular machinery that governs circadian rhythmicity is based on clock gene products organized in regulatory feedback loops. Recently, we have shown that…”
Get full text
Journal Article -
11
5-HT-moduline controls serotonergic activity: implication in neuroimmune reciprocal regulation mechanisms
Published in Progress in neurobiology (01-01-2000)“…The serotonergic neurotransmission is known as a neuromodulatory system exerting its activity in the central nervous system (CNS) as well as at the periphery…”
Get full text
Journal Article -
12
The central role of magnesium deficiency in Tourette's syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette's syndrome and several reported comorbid conditions
Published in Medical hypotheses (01-01-2002)“…Prior studies have suggested a common etiology involved in Tourette's syndrome and several comorbid conditions and symptomatology. Reportedly, current…”
Get full text
Journal Article -
13
Production of Highly Active Antiparasitic Compounds from the Controlled Halogenation of the Arrabidaea brachypoda Crude Plant Extract
Published in Journal of natural products (Washington, D.C.) (25-09-2020)“…Direct halogenation of phenolic compounds present in the CH2Cl2 extract of the roots of Arrabidaea brachypoda was investigated to enhance chemodiversity. The…”
Get full text
Journal Article -
14
Effects of the Inhibition of Cyclo-Oxygenase 1 or 2 or 5-Lipoxygenase on the Activation of the Hypothalamic-Pituitary-Adrenal Axis Induced by Interleukin-1β in the Male Rat
Published in Journal of neuroendocrinology (19-08-2000)“…The limited entry of interleukin‐1β (IL‐1β) into the central nervous system has led to the hypothesis that IL‐1β acts, through IL‐1β receptors located notably…”
Get full text
Journal Article -
15
5-HT1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes: further evidence using 5-HT moduline, polyclonal 5-HT1B receptor antibodies and 5-HT1B receptor knock-out mice
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-2000)“…In previous paper based on classical pharmacological tools, we identified a Gi protein-coupled presynaptic 5-hydroxytryptamine (5-HT) 1B receptor causing…”
Get full text
Journal Article -
16
High impedance fault detection based on linear prediction
Published in Electric power systems research (01-01-2021)“…•High impedance fault detection based only in current signals.•Accuracy: low false positives rate considering similar phenomena.•Technique tested in a database…”
Get full text
Journal Article -
17
Endurance training effects on 5-HT1B receptors mRNA expression in cerebellum, striatum, frontal cortex and hippocampus of rats
Published in Neuroscience letters (06-07-2001)Get full text
Journal Article -
18
5-Hydroxytryptamine-moduline: a novel endogenous peptide involved in the control of anxiety
Published in Neuroscience (01-01-1999)“…The serotonergic system is considered as a neuromodulatory system interacting with other neurotransmissions in the brain and participating in the elaboration…”
Get full text
Journal Article -
19
-
20
Characterization of 5-ht6 receptor and expression of 5-ht6 mRNA in the rat brain during ontogenetic development
Published in Naunyn-Schmiedeberg's archives of pharmacology (16-04-1998)“…We have determined the pharmacological characteristics of the rat 5-ht6 receptor stably expressed in CHO cells. Moreover, using RT-PCR experiments the in vivo…”
Get full text
Journal Article