Search Results - "Grillon, Emmanuelle"
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Intravenous Injection of Clinical Grade Human MSCs After Experimental Stroke: Functional Benefit and Microvascular Effect
Published in Cell transplantation (01-12-2016)“…Stroke is the leading cause of disability in adults. Many current clinical trials use intravenous (IV) administration of human bone marrow-derived mesenchymal…”
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The spatial organization of proton and lactate transport in a rat brain tumor
Published in PloS one (24-02-2011)“…Tumors create a heterogeneous acidic microenvironment which assists their growth and which must be taken into account in the design of drugs and their…”
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Intracerebral injection of human mesenchymal stem cells impacts cerebral microvasculature after experimental stroke: MRI study
Published in NMR in biomedicine (01-12-2012)“…Stroke, the leading cause of disability, lacks treatment beyond thrombolysis. The acute injection of human mesenchymal stem cells (hMSCs) provides a benefit…”
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Magnetic Resonance Imaging and Fluorescence Labeling of Clinical‐Grade Mesenchymal Stem Cells Without Impacting Their Phenotype: Study in a Rat Model of Stroke
Published in Stem cells translational medicine (01-04-2012)“…Human mesenchymal stem cells (hMSCs) have strong potential for cell therapy after stroke. Tracking stem cells in vivo following a graft can provide insight…”
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Blood-brain barrier permeability to manganese and to Gd-DOTA in a rat model of transient cerebral ischaemia
Published in NMR in biomedicine (01-06-2008)“…Loss of integrity of the blood–brain barrier (BBB) and brain swelling is a potentially lethal complication of reperfusion in human stroke. To assess the time…”
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Xenon-129 MR imaging and spectroscopy of rat brain using arterial delivery of hyperpolarized xenon in a lipid emulsion
Published in Magnetic resonance in medicine (01-08-2001)“…Hyperpolarized 129Xe dissolved in a lipid emulsion constitutes an NMR tracer that can be injected into the blood stream, enabling blood‐flow measurement and…”
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Intravenous administration of 99mTc-HMPAO-labeled human mesenchymal stem cells after stroke: in vivo imaging and biodistribution
Published in Cell transplantation (2009)“…Human mesenchymal stem cells (hMSC) are a promising source for cell therapy after stroke. To deliver these cells, an IV injection appears safer than a local…”
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Method to determine in vivo the relaxation time T1 of hyperpolarized xenon in rat brain
Published in Magnetic resonance in medicine (01-06-2003)“…The magnetic polarization of the stable 129Xe isotope may be enhanced dramatically by means of optical techniques and, in principle, hyperpolarized 129Xe MRI…”
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Tissue Oxygen Saturation Mapping with Magnetic Resonance Imaging
Published in Journal of cerebral blood flow and metabolism (01-09-2014)“…A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the investigation of cerebrovascular disease. While positron emission…”
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Microvascular plasticity after experimental stroke: a molecular and MRI study
Published in Cerebrovascular diseases (Basel, Switzerland) (01-12-2014)“…Microvasculature plays a key role in stroke pathophysiology both during initial damage and extended neural repair. Moreover, angiogenesis processes seem to be…”
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Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation
Published in BMC research notes (02-06-2015)“…In cancer cells in vitro, the glycolytic pathway and the mitochondrial tricarboxylic acid (TCA) cycle are programmed to produce more precursor molecules, and…”
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Vessel size imaging
Published in Magnetic resonance in medicine (01-03-2001)“…Vessel size imaging is a new method that is based on simultaneous measurement of the changes ΔR2 and ΔR *2 in relaxation rate constants induced by the…”
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Blood-brain barrier permeability to manganese and to Gd-DOTA in a rat model of transient cerebral ischaemia: BBB permeability after transient cerebral ischemia
Published in NMR in biomedicine (01-06-2008)“…Loss of integrity of the blood-brain barrier (BBB) and brain swelling is a potentially lethal complication of reperfusion in human stroke. To assess the time…”
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Intravenous Administration of Tc-HMPAO-Labeled Human Mesenchymal Stem Cells after Stroke: In Vivo Imaging and Biodistribution
Published in Cell transplantation (01-12-2009)“…Human mesenchymal stem cells (hMSC) are a promising source for cell therapy after stroke. To deliver these cells, an IV injection appears safer than a local…”
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Measuring Hemoglobin Oxygen Saturation During Graded Hypoxic Hypoxia in Rat Striatum
Published in Anesthesia and analgesia (01-02-2006)“…We evaluated in vivo reflectance spectroscopy of visible light as a method to assess brain tissue hemoglobin oxygen saturation in rat striatum (SstrO2). Seven…”
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Method to determine in vivo the relaxation time T 1 of hyperpolarized xenon in rat brain
Published in Magnetic resonance in medicine (01-06-2003)“…The magnetic polarization of the stable 129 Xe isotope may be enhanced dramatically by means of optical techniques and, in principle, hyperpolarized 129 Xe MRI…”
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Focal brain ischemia in rat: acute changes in brain tissueT1 reflect acute increase in brain tissue water content
Published in NMR in biomedicine (01-12-2005)Get full text
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Nuclear factor-κB activation in permanent intraluminal focal cerebral ischemia in the rat
Published in Neuroscience letters (21-07-2000)“…Nuclear factor-κB (NF-κB) is an oxidative stress responsive transcription factor known to be activated in response to transient middle cerebral artery…”
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A model of blood-brain barrier permeability to water: Accounting for blood inflow and longitudinal relaxation effects
Published in Magnetic resonance in medicine (01-06-2002)“…A noninvasive technique for measuring the permeability of the blood–brain barrier (BBB) to water could help to evaluate changes in the functional integrity of…”
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