Search Results - "Grillo, Stephanie L"

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction by Zhou, Mi, Geathers, Jasmine S., Grillo, Stephanie L., Weber, Sarah R., Wang, Weiwei, Zhao, Yuanjun, Sundstrom, Jeffrey M.

“…Retinal pigment epithelial (RPE) cells maintain the health and functional integrity of both photoreceptors and the choroidal vasculature. Loss of RPE…”
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Editorial: Women in retina: 2022 by Edwards, Genea, Grillo, Stephanie L

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Neurodegeneration, Neuroprotection and Regeneration in the Zebrafish Retina by Stella, Jr, Salvatore L, Geathers, Jasmine S, Weber, Sarah R, Grillo, Michael A, Barber, Alistair J, Sundstrom, Jeffrey M, Grillo, Stephanie L

“…Neurodegenerative retinal diseases, such as glaucoma and diabetic retinopathy, involve a gradual loss of neurons in the retina as the disease progresses…”
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Extracellular vesicles from retinal pigment epithelial cells expressing R345W‐Fibulin‐3 induce epithelial‐mesenchymal transition in recipient cells by Zhou, Mi, Zhao, Yuanjun, Weber, Sarah R., Gates, Christopher, Carruthers, Nicholas J., Chen, Han, Liu, Xiaoming, Wang, Hong‐Gang, Ford, Michael, Swulius, Matthew T., Barber, Alistair J., Grillo, Stephanie L., Sundstrom, Jeffrey M.

“…Abstract We have shown previously that expression of R345W‐Fibulin‐3 induces epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells…”
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Expression of R345W-Fibulin-3 Induces Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by Zhou, Mi, Weber, Sarah R, Zhao, Yuanjun, Chen, Han, Barber, Alistair J, Grillo, Stephanie L, Wills, Carson A, Wang, Hong Gang, Hulleman, John D, Sundstrom, Jeffrey M

“…To investigate the role of protein misfolding in retinal pigment epithelial (RPE) cell dysfunction, the effects of R345W-Fibulin-3 expression on RPE cell…”
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Psychophysical testing in rodent models of glaucomatous optic neuropathy by Grillo, Stephanie L., Koulen, Peter

“…Processing of visual information begins in the retina, with photoreceptors converting light stimuli into neural signals. Ultimately, signals are transmitted to…”
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Descriptive analysis of Fibulin-3 and the extracellular vesicle marker, Alix, in drusen from a small cohort of postmortem human eyes by Grillo, Stephanie L., Etzel, Justin D., Weber, Sarah R., Ondeck, Cassandra, Wang, Weiwei, Zhao, Yuanjun, Barber, Alistair J., Sundstrom, Jeffrey M.

“…Fibulin-3 (Fib3) is a secreted glycoprotein that is expressed in the retina and has been associated with drusen formation in age-related macular degeneration…”
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Quantification of Changes in Visual Function During Disease Development in a Mouse Model of Pigmentary Glaucoma by Grillo, Stephanie L, Montgomery, Christa L, Johnson, Heather M, Koulen, Peter

“…PURPOSE:We investigated the relationship between visual parameters that are commonly affected during glaucomatous disease progression with functional measures…”
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A short period of dark-adaptation is sufficient to generate light-induced photoreceptor degeneration in pigmented zebrafish by Khan, Amanda S., Friemel, Taylor D., Grillo, Stephanie L., Stella, Salvatore L.

“…Light-induced retinal degeneration (LIRD) models are used to recapitulate the pathologies of retinal diseases that affect photoreceptors. Current LIRD models…”
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Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin by Grillo, Michael A., Grillo, Stephanie L., Gerdes, Bryan C., Kraus, Jacob G., Koulen, Peter

“…Calsenilin is a calcium ion (Ca 2+ )-binding protein involved in regulating the intracellular concentration of Ca 2+ , a second messenger that controls…”
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Changes in Retinal N-Acylethanolamines and their Oxylipin Derivatives During the Development of Visual Impairment in a Mouse Model for Glaucoma by Montgomery, Christa L., Keereetaweep, Jantana, Johnson, Heather M., Grillo, Stephanie L., Chapman, Kent D., Koulen, Peter

“…Neurons are especially susceptible to oxidative damage, which is increasingly implicated in neurodegenerative disease. Certain N -acylethanolamines (NAEs) have…”
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Adenosine receptor expression in the adult zebrafish retina by Grillo, Stephanie L., McDevitt, Dillon S., Voas, Matthew G., Khan, Amanda S., Grillo, Michael A., Stella, Salvatore L.

“…Adenosine is an endogenous nucleoside in the central nervous system that acts on adenosine receptors. These are G protein-coupled receptors that have four…”
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Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damage and photoreceptor loss by Subrahmanian, Sandeep M, Yerlikaya, Esma I, Sunilkumar, Siddharth, Toro, Allyson L, McCurry, Christopher M, Grillo, Stephanie L, Barber, Alistair J, Sundstrom, Jeffrey M, Dennis, Michael D

“…Age-related macular degeneration (AMD) is a leading cause of blindness in elderly populations, yet the molecular events that initiate the early retinal defects…”
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Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model by Kaja, Simon, Naumchuk, Yuliya, Grillo, Stephanie L., Borden, Priscilla K., Koulen, Peter

“…•Vesl-1L/Homer-1c expression in increased in the retina of glaucomatous DBA/2J mice.•Vesl-1L/Homer-1c expression correlates with functional markers of glaucoma…”
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N-Palmitoylethanolamine depot injection increased its tissue levels and those of other acylethanolamide lipids by Grillo, Stephanie L, Keereetaweep, Jantana, Grillo, Michael A, Chapman, Kent D, Koulen, Peter

“…N-Palmitoylethanolamine (NAE 16:0) is an endogenous lipid signaling molecule that has limited water solubility, and its action is short-lived due to its rapid…”
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Melanopsin retinal ganglion cells are not labeled in Thy-1 YFP-16 transgenic mice by Grillo, Stephanie L., Stella, Salvatore L.

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Melanopsin retinal ganglion cells are not labeled in Thy-1YFP-16 transgenic mice by Grillo, Stephanie L, Stella, Salvatore L

“…Retinal ganglion cells (RGCs) that express the photopigment melanopsin (mRGCs) are photosensitive and initiate the non-image-forming pathway, where the…”
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