Search Results - "Grillet, B."

A two-step treatment strategy trial in patients with early arthritis aimed at achieving remission: the IMPROVED study by Heimans, L, Wevers-de Boer, K V C, Visser, K, Goekoop, R J, van Oosterhout, M, Harbers, J B, Bijkerk, C, Speyer, I, de Buck, M P D M, de Sonnaville, P B J, Grillet, B A M, Huizinga, T W J, Allaart, C F

“…To assess which treatment strategy is most effective in inducing remission in early (rheumatoid) arthritis. 610 patients with early rheumatoid arthritis (RA…”
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Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis by van der Kooij, S M, Goekoop-Ruiterman, Y P M, de Vries-Bouwstra, J K, Güler-Yüksel, M, Zwinderman, A H, Kerstens, P J S M, van der Lubbe, P A H M, de Beus, W M, Grillet, B A M, Ronday, H K, Huizinga, T W J, Breedveld, F C, Dijkmans, B A C, Allaart, C F

“…To compare the occurrence of drug-free remission, functional ability and radiological damage after 4 years of response-driven treatment according to four…”
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Induction therapy with a combination of DMARDs is better than methotrexate monotherapy: first results of the tREACH trial by de Jong, P H, Hazes, J M, Barendregt, P J, Huisman, M, van Zeben, D, van der Lubbe, P A, Gerards, A H, de Jager, M H, de Sonnaville, P B, Grillet, B A, Luime, J J, Weel, A E

“…To determine the most effective induction disease-modifying antirheumatic drug (DMARD) strategy in early rheumatoid arthritis (RA), second to compare one…”
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Performance evaluation of the new Access HIV Ag/Ab combo assay on the DxI 9000 Access Immunoassay Analyzer by Lemée, V., Gréaume, S., Gautier, J., Dzamitika, S.A., Coignard, C., Jortani, S.A., Grillet, B., Badawi, M., Plantier, J-C.

“…•WHO p24 Ag analytical sensitivity with the Access combo assay was 0.22 IU/mL.•The assay detected up to 11 of the 30 seroconversion panels earlier vs other…”
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Tapering conventional synthetic DMARDs in patients with early arthritis in sustained remission: 2-year follow-up of the tREACH trial by Kuijper, T M, Luime, J J, de Jong, P H P, Gerards, A H, van Zeben, D, Tchetverikov, I, de Sonnaville, P B J, van Krugten, M V, Grillet, B A, Hazes, J M W, Weel, A E A M

“…With early and intensive treatment many patients with early RA attain remission. Aims were to investigate (1) the frequency and time to sustained remission and…”
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Rheumatologists’ adherence to a disease activity score steered treatment protocol in early arthritis patients is less if the target is remission by Akdemir, G., Markusse, I.M., Goekoop-Ruiterman, Y.P.M., Steup-Beekman, G.M., Grillet, B.A.M., Kerstens, P.J.S.M., Lems, W.F., Huizinga, T.W.J., Allaart, C.F.

“…To compare rheumatologists’ adherence to treatment protocols for rheumatoid arthritis (RA) targeted at Disease Activity Score (DAS) ≤2.4 or <1.6. The…”
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Can we prevent rapid radiological progression in patients with early rheumatoid arthritis? by Heimans, L., Boer, K. V. C. Wevers-de, Ronday, H. K., Collée, G., de Sonnaville, P. B. J., Grillet, B. A. M., Huizinga, T. W. J., Allaart, C. F.

“…The aim of this study is to test the performance of a matrix model to predict rapid radiological progression (RRP) in a study population of early rheumatoid…”
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Gelatinase B participates in collagen II degradation and releases glycosylated remnant epitopes in rheumatoid arthritis by Van den Steen, P E, Grillet, B, Opdenakker, G

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B-058 Multicenter Evaluation of the new Access HIV Ag/Ab combo Assay With Highly Sensitive HIV-1 p24 Antigen Detection on the DxI 9000 Access Immunoassay Analyzer by Grillet, B, Jortani, S A, Christenson, R H, Apple, F S, Plantier, J C

“…Abstract Background Beckman Coulter developed a fully automated Access HIV Ag/Ab combo assay for the new DxI 9000 Access Immunoassay analyzer that reports…”
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Rehabilitation program improves quality of life in fibromyalgia patients up to one year: Preliminary results by Jacobs, H., Grillet, B., De Bacquer, D.

“…Cognitive behaviour therapy (CBT) and graded activity (GA) have a beneficial effect on the Quality of life (QoL) of patients with fibromyalgia. However the…”
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Intra-articular steroid injection. A risk-benefit assessment by Grillet, B, Dequeker, J

“…Intra-articular injections with steroids may offer additional help in the treatment of inflammatory joint diseases. The major side effects are the systemic…”
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Development and application of a radioimmunoassay for interleukin-8: detection of interleukin-8 in synovial fluids from patients with inflammatory joint disease by Rampart, M, Herman, A G, Grillet, B, Opdenakker, G, Van Damme, J

“…A sensitive and specific radioimmunoassay for human interleukin-8 (IL-8) was developed using isotopically labeled homogenous natural protein. The detection…”
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Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: anti-rheumatic activity by protease inhibition by Norga, K, Grillet, B, Masure, S, Paemen, L, Opdenakker, G

“…The direct and indirect inhibitory potential of D-penicillamine toward human neutrophil and synovial fluid gelatinase B, a marker enzyme for disease severity…”
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Cleavage of denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post‐translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis by Van den Steen, Philippe E., Proost, Paul, Grillet, Bernard, Brand, David D., Rang, Andrew H., Van Damme, Jo, Opdenakker, Ghislain

“…ABSTRACT During acute inflammation, leukocytes release proteolytic enzymes including matrix metalloproteinases (MMPs), but the physiopathological mechanisms…”
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Large-joint damage in patients with early rheumatoid arthritis and its association with treatment strategy and damage of the small joints by DIRVEN, Linda, VAN DEN BROEK, Marianne, KROON, Herman M, GRILLET, Bernard A. M, HUUB HAN, K, KERSTENS, Pit J. S. M, HUIZINGA, Tom W. J, LEMS, Willem F, ALLAART, Cornelia F

“…To determine the prevalence of large-joint damage and the association with small-joint damage in patients with RA after 8 years of low DAS (≤2.4)-targeted…”
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Microbial Toll‐like receptor ligands differentially regulate CXCL10/IP‐10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN‐γ and provide a mechanism for enhanced synovial chemokine levels in septic arthritis by Proost, Paul, Vynckier, An‐Katrien, Mahieu, Frank, Put, Willy, Grillet, Bernard, Struyf, Sofie, Wuyts, Anja, Opdenakker, Ghislain, Damme, Jo Van

“…The CXC chemokine IFN‐γ‐inducible protein‐10 (IP‐10/CXCL10) activates CXC chemokine receptor 3 (CXCR3) and attracts activated T cells and natural killer cells…”
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Patient preferences for treatment: report from a randomised comparison of treatment strategies in early rheumatoid arthritis (BeSt trial) by Goekoop-Ruiterman, Yvonne P M, de Vries-Bouwstra, Jeska K, Allaart, Cornelia F, Kerstens, Pit J S M, Grillet, Bernard A M, de Jager, Mike H, Han, K Huub, Speyer, Irene, van der Lubbe, Peter A H M, Seys, Patrick E H, Breedveld, Ferdinand C, Dijkmans, Ben A C

“…Objective: To determine treatment preferences among patients with recent onset rheumatoid arthritis participating in a randomised controlled trial comparing…”
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Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-γ in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids by Proost, Paul, Verpoest, Sara, De Borne, Kirsten Van, Schutyser, Evemie, Struyf, Sofie, Put, Willy, Ronsse, Isabelle, Grillet, Bernard, Opdenakker, Ghislain, Damme, Jo Van

“…The synovial cavity constitutes the ideal stage to study the interplay between microbial Toll‐like receptor (TLR) ligands and cytokines. Infiltrated leukocytes…”
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Spontaneous regression of lung metastases of adenoid cystic carcinoma by Grillet, B, Demedts, M, Roelens, J, Goddeeris, P, Fossion, E

“…Two patients with spontaneous regression of histologically confirmed lung metastases from a classic cribriform adenoid cystic carcinoma are presented. The…”
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Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis by Opdenakker, G, Masure, S, Grillet, B, Van Damme, J

“…Gelatinases (type IV collagenases) produced by normal peripheral blood leukocytes were studied by the use of a substrate conversion assay. When monocytes were…”
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