Search Results - "Grill, Raymond J."

Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats by Dash, Pramod K, Orsi, Sara A, Zhang, Min, Grill, Raymond J, Pati, Shibani, Zhao, Jing, Moore, Anthony N

“…Traumatic brain injury (TBI) initiates a complex series of neurochemical and signaling changes that lead to pathological events including neuronal…”
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RhoA-ROCK Inhibition Reverses Synaptic Remodeling and Motor and Cognitive Deficits Caused by Traumatic Brain Injury by Mulherkar, Shalaka, Firozi, Karen, Huang, Wei, Uddin, Mohammad Danish, Grill, Raymond J., Costa-Mattioli, Mauro, Robertson, Claudia, Tolias, Kimberley F.

“…Traumatic brain injury (TBI) causes extensive neural damage, often resulting in long-term cognitive impairments. Unfortunately, effective treatments for TBI…”
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Human Neural Stem Cell Transplantation-Mediated Alteration of Microglial/Macrophage Phenotypes after Traumatic Brain Injury by Gao, Junling, Grill, Raymond J, Dunn, Tiffany J, Bedi, Supinder, Labastida, Javier Allende, Hetz, Robert A, Xue, Hasen, Thonhoff, Jason R, DeWitt, Douglas S, Prough, Donald S, Cox, Jr, Charles S, Wu, Ping

“…Neural stem cells (NSCs) promote recovery from brain trauma, but neuronal replacement is unlikely the sole underlying mechanism. We hypothesize that grafted…”
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Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome by Dash, Pramod K, Johnson, Daniel, Clark, Jordan, Orsi, Sara A, Zhang, Min, Zhao, Jing, Grill, Raymond J, Moore, Anthony N, Pati, Shibani

“…Traumatic brain injury (TBI) sets in motion cascades of biochemical changes that result in delayed cell death and altered neuronal architecture. Studies have…”
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Analysis of functional pathways altered after mild traumatic brain injury by Redell, John B, Moore, Anthony N, Grill, Raymond J, Johnson, Daniel, Zhao, Jing, Liu, Yin, Dash, Pramod K

“…Concussive injury (or mild traumatic brain injury; mTBI) can exhibit features of focal or diffuse injury patterns. We compared and contrasted the cellular and…”
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Energy balance following diets of varying fat content: metabolic dysregulation in a rodent model of spinal cord contusion by Harris, Kwamie K., Himel, Alexandra R., Duncan, Brittany C., Grill, Raymond J., Grayson, Bernadette E.

“…Within the spinal cord injured (SCI) population, metabolic dysfunction may be exacerbated. Models of cord injury coupled with metabolic stressors have…”
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P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury by Vita, Sydney M, Redell, John B, Maynard, Mark E, Zhao, Jing, Grill, Raymond J, Dash, Pramod K, Grayson, Bernadette E

“…Athletes participating in contact sports are at risk for sustaining repeat mild traumatic brain injury (rmTBI). Unfortunately, no pharmacological treatment to…”
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Delayed Systemic Treatment with Cannabinoid Receptor 2 Agonist Mitigates Spinal Cord Injury-Induced Osteoporosis More Than Acute Treatment Directly after Injury by Tucci, Michelle A, Pride, Yilianys, Strickland, Suzanne, Marocho, Susanna M Salazar, Jackson, Ramon J, Jefferson, Joshua R, Chade, Alejandro R, Grill, Raymond J, Grayson, Bernadette E

“…Nearly all persons with spinal cord injury (SCI) will develop osteoporosis following injury, and further, up to 50% of all persons with SCI will sustain a…”
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Spinal cord injury causes sustained disruption of the blood-testis barrier in the rat by Dulin, Jennifer N, Moore, Meredith L, Gates, Kevin W, Queen, Joanna H, Grill, Raymond J

“…There is a high incidence of infertility in males following traumatic spinal cord injury (SCI). Quality of semen is frequently poor in these patients, but the…”
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High-density microarray analysis of hippocampal gene expression following experimental brain injury by Matzilevich, David A., Rall, Jason M., Moore, Anthony N., Grill, Raymond J., Dash, Pramod K.

“…Behavioral, biophysical, and pharmacological studies have implicated the hippocampus in the formation and storage of spatial memory. Traumatic brain injury…”
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Acute damage to the blood–brain barrier and perineuronal net integrity in a clinically-relevant of rat model traumatic brain by Vita, Sydney M, Grayson, Bernadette E, Grill, Raymond J

“…Closed-head, frontal impacts in which the brain undergoes both lateral and rotational acceleration comprise the majority of human traumatic brain injury (TBI)…”
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Acute damage to the blood–brain barrier and perineuronal net integrity in a clinically-relevant rat model of traumatic brain injury by Vita, Sydney M., Grayson, Bernadette E., Grill, Raymond J.

“…Closed-head, frontal impacts in which the brain undergoes both lateral and rotational acceleration comprise the majority of human traumatic brain injury (TBI)…”
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High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury by Khaing, Zin Z, Milman, Brian D, Vanscoy, Jennifer E, Seidlits, Stephanie K, Grill, Raymond J, Schmidt, Christine E

“…A major hurdle for regeneration after spinal cord injury (SCI) is the ability of axons to penetrate and grow through the scar tissue. After SCI, inflammatory…”
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Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury by Haber, Margalit, Abdel Baki, Samah G., Grin'kina, Natalia M., Irizarry, Rachel, Ershova, Alina, Orsi, Sara, Grill, Raymond J., Dash, Pramod, Bergold, Peter J.

“…Traumatic brain injury (TBI) differs in severity from severe to mild. This study examined whether a combination of the drugs minocycline (MINO) plus…”
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Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury by Dulin, Jennifer N, Karoly, Edward D, Wang, Ying, Strobel, Henry W, Grill, Raymond J

“…Inflammation is a major factor shaping outcome during the early, acute phase of traumatic spinal cord injury (SCI). It is known that pro-inflammatory signaling…”
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Chronic spontaneous activity generated in the somata of primary nociceptors is associated with pain-related behavior after spinal cord injury by Bedi, Supinder S, Yang, Qing, Crook, Robyn J, Du, Junhui, Wu, Zizhen, Fishman, Harvey M, Grill, Raymond J, Carlton, Susan M, Walters, Edgar T

“…Mechanisms underlying chronic pain that develops after spinal cord injury (SCI) are incompletely understood. Most research on SCI pain mechanisms has focused…”
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Changes in Gene Expression and Metabolism in the Testes of the Rat following Spinal Cord Injury by Fortune, Ryan D, Grill, Raymond J, Beeton, Christine, Tanner, Mark, Huq, Redwan, Loose, David S

“…Spinal cord injury (SCI) results in devastating changes to almost all aspects of a patient's life. In addition to a permanent loss of sensory and motor…”
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The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord by Dulin, Jennifer N, Moore, Meredith L, Grill, Raymond J

“…There are currently no proven effective treatments that can improve recovery of function in spinal cord injury (SCI) patients. Many therapeutic compounds have…”
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Chronic spinal cord changes in a high-fat diet-fed male rat model of thoracic spinal contusion by Spann, Redin A, Lawson, William J, Grill, Raymond J, Garrett, Michael R, Grayson, Bernadette E

“…Individuals that suffer injury to the spinal cord can result in long-term, debilitating sequelae. Spinal cord-injured patients have increased risk for the…”
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Histopathological and behavioral effects of immediate and delayed hemorrhagic shock after mild traumatic brain injury in rats by Navarro, Jovany Cruz, Pillai, Shibu, Cherian, Leela, Garcia, Robert, Grill, Raymond J, Robertson, Claudia S

“…The purpose of this study was to investigate the increased susceptibility of the brain, after a controlled mild cortical impact injury, to a secondary ischemic…”
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