Search Results - "Grill, Jessica I"

Loss of DRO1/CCDC80 results in obesity and promotes adipocyte differentiation by Grill, Jessica I., Neumann, Jens, Herbst, Andreas, Ofner, Andrea, Hiltwein, Felix, Marschall, Maximilian K., Zierahn, Heike, Wolf, Eckhard, Schneider, Marlon R., Kolligs, Frank T.

“…To investigate the role of DRO1 in obesity and adipogenesis in vivo, we generated a constitutive Dro1 knockout mouse model and analyzed the effect of DRO1 loss…”
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Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice by Grill, Jessica I, Neumann, Jens, Ofner, Andrea, Marschall, Maximilian K, Zierahn, Heike, Herbst, Andreas, Wolf, Eckhard, Kolligs, Frank T

“…This study demonstrates DRO1 to be a strong tumor suppressor in chemically induced colon carcinogenesis. Loss of DRO1 increases multiplicity of preneoplastic…”
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Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis by Grill, Jessica I., Neumann, Jens, Hiltwein, Felix, Kolligs, Frank T., Schneider, Marlon R.

“…Background E-cadherin is a cell adhesion protein with crucial roles in development, tissue homeostasis, and disease. Loss of E-cadherin in the adult intestinal…”
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Inactivation of Itf2 promotes intestinal tumorigenesis in Apc(Min/+) mice by Grill, Jessica I, Herbst, Andreas, Brandl, Lydia, Kong, Lixia, Schneider, Marlon R, Kirchner, Thomas, Wolf, Eckhard, Kolligs, Frank T

“…Deregulation of Wnt/β-catenin signaling following inactivation of the adenomatous polyposis coli (APC) tumor suppressor gene is frequently found in colorectal…”
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DRO1 inactivation drives colorectal carcinogenesis in ApcMin/+ mice by Grill, Jessica I, Neumann, Jens, Herbst, Andreas, Hiltwein, Felix, Ofner, Andrea, Marschall, Maximilian K, Wolf, Eckhard, Kirchner, Thomas, Göke, Burkhard, Schneider, Marlon R, Kolligs, Frank T

“…Colorectal cancer develops from adenomatous precursor lesions by a multistep process that involves several independent mutational events in oncogenes and tumor…”
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Inactivation of Itf2 promotes intestinal tumorigenesis in ApcMin/+ mice by Grill, Jessica I., Herbst, Andreas, Brandl, Lydia, Kong, Lixia, Schneider, Marlon R., Kirchner, Thomas, Wolf, Eckhard, Kolligs, Frank T.

“…Deregulation of Wnt/β-catenin signaling following inactivation of the adenomatous polyposis coli (APC) tumor suppressor gene is frequently found in colorectal…”
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DRO1/CCDC80: a Novel Tumor Suppressor of Colorectal Carcinogenesis by Grill, Jessica I., Kolligs, Frank T.

“…Dro1/Ccdc80 has been identified as a tumor suppressor gene in colorectal, thyroid, and ovarian cancer. Dro1/Ccdc80 is ubiquitously expressed and has, next to…”
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