Search Results - "Grigoryan, Rita S."
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Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines
Published in PloS one (02-12-2013)“…Despite intensive treatment with chemotherapy, radiotherapy and surgery, over 70% of patients with metastatic Ewing's Sarcoma Family of Tumors (EFT) will die…”
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Deamination of Glutamine is a Prerequisite for Optimal Asparagine Deamination by Asparaginases In Vivo (CCG-1961)
Published in Anticancer research (01-03-2004)“…Background: Glutamine (Gln) deamination by asparaginase (ASNase) appears to contribute in the decrease of serum asparagine (Asn) levels and enhance leukemic…”
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Flow cytometry analysis of single-strand DNA damage in neuroblastoma cell lines using the F7-26 monoclonal antibody
Published in Cytometry. Part A (01-11-2007)“…The F7-26 monoclonal antibody (Mab) has been reported to be specific for single-strand DNA damage (ssDNA) and to also identify cells in apoptosis. We…”
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Changes of Amino Acid Serum Levels in Pediatric Patients with Higher-risk Acute Lymphoblastic Leukemia (CCG-1961)
Published in In vivo (Athens) (01-03-2004)“…Background: Deamination of asparagine (Asn) and glutamine (Gln) by asparaginases (ASNase) is associated with good prognosis in acute lymphoblastic leukemia…”
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Pharmacokinetics and Pharmacodynamics of Three Asparaginases in Pediatric Patients with Higher Risk Acute Lymphoblastic Leukemia: A Report from CCG-1961
Published in Blood (16-11-2004)“…Deamination of asparagine (Asn) and glutamine (Gln) by asparaginase (ASNase) induces apoptosis of ALL lymphoblasts, which lack ability to synthesize Asn…”
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