Search Results - "Grigorova, N."

Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia by Agalakova, Natalia I, Grigorova, Yulia N, Ershov, Ivan A, Reznik, Vitaly A, Mikhailova, Elena V, Nadei, Olga V, Samuilovskaya, Leticia, Romanova, Larisa A, Adair, C David, Romanova, Irina V, Bagrov, Alexei Y

“…Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Recently, we…”
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Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats by Grigorova, Yulia N, Wei, Wen, Petrashevskaya, Natalia, Zernetkina, Valentina, Juhasz, Ondrej, Fenner, Rachel, Gilbert, Christian, Lakatta, Edward G, Shapiro, Joseph I, Bagrov, Alexei Y, Fedorova, Olga V

“…High salt (HS) intake stimulates the production of marinobufagenin (MBG), an endogenous steroidal Na/K-ATPase ligand, which activates profibrotic signaling. HS…”
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Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats by Grigorova, Yulia N, Juhasz, Ondrej, Long, Jeffrey M, Zernetkina, Valentina I, Hall, Mikayla L, Wei, Wen, Morrell, Christopher H, Petrashevskaya, Natalia, Morrow, Audrey, LaNasa, Katherine H, Bagrov, Alexei Y, Rapp, Peter R, Lakatta, Edward G, Fedorova, Olga V

“…The hypertensive response in Dahl salt-sensitive (DSS) rats on a high-salt (HS) diet is accompanied by central arterial stiffening (CAS), a risk factor for…”
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Co-administration of oleic and docosahexaenoic acids enhances glucose uptake rather than lipolysis in mature 3T3-L1 adipocytes cell culture by Grigorova, N., Ivanova, Zh, Vachkova, E., Tacheva, T., Penchev Georgiev, I.

“…This study investigated the effect of different types of long-chain fatty acids and their combination on the triglyceride accumulation, glucose utilisation,…”
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Culturing of primary bovine mammary epithelial cells and validation of biotransformation capacity in experiments with enrofloxacin by Vachkova, E., Vasilev, N., Grigorova, N., Milanova, A.

“…Many drugs and toxic compounds are subjected to disposition and metabolism in bovine mammary epithelial cells (bMECs). For rapid investigation of different…”
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Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension by Zhang, Yongqing, Wei, Wen, Shilova, Victoria, Petrashevskaya, Natalia N, Zernetkina, Valentina I, Grigorova, Yulia N, Marshall, Courtney A, Fenner, Rachel C, Lehrmann, Elin, Wood, 3rd, William H, Becker, Kevin G, Lakatta, Edward G, Bagrov, Alexei Y, Fedorova, Olga V

“…Background Elevated levels of an endogenous Na/K-ATPase inhibitor marinobufagenin accompany salt-sensitive hypertension and are implicated in cardiac fibrosis…”
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Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia by Fedorova, Olga V, Ishkaraeva, Valentina V, Grigorova, Yulia N, Reznik, Vitaly A, Kolodkin, Nikolai I, Zazerskaya, Irina E, Zernetkina, Valentina, Agalakova, Natalia I, Tapilskaya, Natalia I, Adair, C David, Lakatta, Edward G, Bagrov, Alexei Y

“…Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE)…”
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Effect of fish oil supplementation and restricted feeding on body fat distribution and blood lipid profile in a rabbit model of castration-induced obesity by Grigorova, N., Ivanova, Zh, Bjorndal, B., Vachkova, E., Penchev, G., Berge, R., Ribarski, S., Georgieva, T. Mircheva, Yonkova, P., Georgiev, I. Penchev

“…This study investigates the effect of fish oil supplementation and restricted feeding on body fat distribution and blood lipid profile in experimentally…”
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Adipogenic potential of stem cells derived from rabbit subcutaneous and visceral adipose tissue in vitro by Vachkova, Ekaterina, Bosnakovski, D., Yonkova, P., Grigorova, N., Ivanova, Zh, Todorov, P., Penchev, G., Milanova, A., Simeonova, G., Stanilova, S., Georgiev, I. Penchev

“…Rabbits are considered as appropriate animal models to study some obesity-associated abnormalities because of the similarity of their blood lipid profile and…”
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Eicosapentaenoic acid provokes stronger in vitro antiadipogenic effect than docosahexaenoic acid in differentiated 3T3-L1 cells by Vachkova, E., Yonkova, P., Grigorova, N., Ivanova, Zh, Penchev, G., Bivolarski, B., Stanilova, S., Georgiev, I.P.

“…The comparative studies of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) effects on the amount of lipid droplets (LD) and within adipocytes are…”
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Magnesium Sulfate Potentiates Effect of Digifab on Marinobufagenin-Induced Na/K-ATPase Inhibition by Zazerskaya, Irina E., Ishkaraeva, Valentina V., Frolova, Elena V., Solodovnikova, Nelly G., Grigorova, Yulia N., David Adair, C., Fedorova, Olga V., Bagrov, Alexei Y.

“…BACKGROUND Immunoneutralization of elevated circulating levels of endogenous digitalis-like Na/K-ATPase inhibitors (i.e. cardiotonic steroids (CTS)) represents…”
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Morphological study on periadventitial adipose tissue of the aortic arch in a rabbit model of obesity: Preliminary results by Penchev, G., Yonkova, P., Ribarski, S., Kostov, D., Vachkova, E., Grigorova, N., Georgieva, T., Ivanova, Zh, Georgiev, I.

“…This study was conducted to evaluate the effect of obesity on some morphological features of periad-ventitial adipose tissue in the aortic arch region. Twelve…”
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The effect of antioxidant treatment on blood lactate and pyruvate concentrations in a rabbit model of obesity by N. Grigorova, Zh. Ivanova, E. Dishlianova, T. Georgieva, T. Georgieva, T. Slavov, E. Vachkova, I. Penchev Georgiev

“…In the current study, the impact of dietary antioxidant supplementation on fasting blood lactate and pyruvate concentrations in a rabbit model of obesity was…”
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Distribution of dirofilariasis in Omsk region by Ryazanova, T. S., Sverdlova, A. V., Starostina, O. Yu, Nikitin, A. A., Grigorova, N. Yu, Kochetkov, Yu. V.

“…Background. Recently, in the Russian Federation, there has been a tendency to an increase in the number of registered cases of dirofilariasis among residents…”
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Treatment of cryptorchidism in pediatric surgical practice: a multicenter study by Axelrov, M. A., Minaev, S. V., Razin, M. P., Yusupov, Sh. A., Tsap, N. A., Tarakanov, V. A., Shamsiev, J. A., Karpova, I. Yu, Smolentsev, M. M., Sergienko, T. V., Baturov, M. A., Daniyarov, E. S., Strizhenok, D. S., Grigoruk, E. H., Mikhalev, O. Yu, Komarova, S. Yu, Bykov, N. I., Barova, N. K., Trushin, P. V., Gramzin, A. V., Aslanov, D. A., Grigorova, A. N.

“…Introduction . Cryptorchidism is a common disease in pediatric urological and andrological practice since the issues of tactical approaches and its optimal…”
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Dementia associated with chronic kidney disease is accompanied by increase in plasma amyloid beta and cardiovascular dysfunction by Fedorova, Olga V, Lakhani, Hari Vishal, Thompson, Ellen, Wei, Wen, Grigorova, Yulia N, Lakatta, Edward G, Sodhi, Komal

“…Background In end‐stage chronic kidney disease (CKD) the prevalence of cognitive impairment (CI) has been estimated at 30‐60%. Cardiovascular diseases (CVD)…”
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Association of central arterial stiffness with hippocampal blood flow and N-acetyl aspartate concentration in hypertensive adult Dahl salt sensitive rats by Ajamu, Samuel O., Fenner, Rachel C., Grigorova, Yulia N., Cezayirli, Defne, Morrell, Christopher H., Lakatta, Edward G., Bouhrara, Mustapha, Spencer, Richard G., Fedorova, Olga V., Fishbein, Kenneth W.

“…Central arterial stiffness (CAS) is associated with elevated arterial blood pressure (BP) and is likely associated with stiffening of cerebral artery walls,…”
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Cardiotonic Steroids Induce Vascular Fibrosis Via Pressure-Independent Mechanism in NaCl-Loaded Diabetic Rats by Fedorova, Olga V, Fadeev, Artem V, Grigorova, Yulia N, Marshall, Courtney A, Zernetkina, Valentina, Kolodkin, Nikolai I, Agalakova, Natalia I, Konradi, Alexandra O, Lakatta, Edward G, Bagrov, Alexei Y

“…Endogenous cardiotonic steroid, marinobufagenin (MBG), induces Fli1-dependent tissue fibrosis. We hypothesized that an increase in MBG initiates the…”
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Aortic Fibrosis, Induced by High Salt Intake in the Absence of Hypertensive Response, Is Reduced by a Monoclonal Antibody to Marinobufagenin by Grigorova, Yulia N., Juhasz, Ondrej, Zernetkina, Valentina, Fishbein, Kenneth W., Lakatta, Edward G., Fedorova, Olga V., Bagrov, Alexei Y.

“…BACKGROUND Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension,…”
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Marinobufagenin-induced vascular fibrosis is a likely target for mineralocorticoid antagonists by Fedorova, Olga V, Emelianov, Igor V, Bagrov, Konstantin A, Grigorova, Yulia N, Wei, Wen, Juhasz, Ondrej, Frolova, Elena V, Marshall, Courtney A, Lakatta, Edward G, Konradi, Alexandra O, Bagrov, Alexei Y

“…OBJECTIVE:Endogenous cardiotonic steroids, including marinobufagenin (MBG), stimulate vascular synthesis of collagen. Because mineralocorticoid antagonists…”
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