Search Results - "Grigor’ev, Igor A."

EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines by Dikalov, Sergey I, Kirilyuk, Igor A, Voinov, Maxim, Grigor'ev, Igor A

“…Superoxide (O₂ⁱ⁻) has been implicated in the pathogenesis of many human diseases, but detection of the O(2)(•-) radicals in biological systems is limited due…”
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In Vivo Proton–Electron Double-Resonance Imaging of Extracellular Tumor pH Using an Advanced Nitroxide Probe by Samouilov, Alexandre, Efimova, Olga V, Bobko, Andrey A, Sun, Ziqi, Petryakov, Sergey, Eubank, Timothy D, Trofimov, Dmitrii G, Kirilyuk, Igor A, Grigor’ev, Igor A, Takahashi, Wataru, Zweier, Jay L, Khramtsov, Valery V

“…A variable radio frequency proton–electron double-resonance imaging (VRF PEDRI) approach for pH mapping of aqueous samples has been recently developed (Efimova…”
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In vivo monitoring of pH, redox status, and glutathione using L-band EPR for assessment of therapeutic effectiveness in solid tumors by Bobko, Andrey A., Eubank, Timothy D., Voorhees, Jeffrey L., Efimova, Olga V., Kirilyuk, Igor A., Petryakov, Sergey, Trofimiov, Dmitrii G., Marsh, Clay B., Zweier, Jay L., Grigor'ev, Igor A., Samouilov, Alexandre, Khramtsov, Valery V.

“…Approach for in vivo real‐time assessment of tumor tissue extracellular pH (pHe), redox, and intracellular glutathione based on L‐band EPR spectroscopy using…”
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Does scavenging of mitochondrial superoxide attenuate cancer prosurvival signaling pathways? by Nazarewicz, Rafal R, Dikalova, Anna, Bikineyeva, Alfiya, Ivanov, Sergey, Kirilyuk, Igor A, Grigor'ev, Igor A, Dikalov, Sergey I

“…It has been previously suggested that overexpression of mitochondrial superoxide dismutase (SOD) attenuates cancer development; however, the exact mechanism…”
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Reversible reduction of nitroxides to hydroxylamines: Roles for ascorbate and glutathione by Bobko, Andrey A., Kirilyuk, Igor A., Grigor’ev, Igor A., Zweier, Jay L., Khramtsov, Valery V.

“…Biological applications of stable nitroxyl radicals, NR, include their use as contrast agents for magnetic resonance imaging, spin labels, superoxide dismutase…”
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Antioxidant and antitumor activity of trolox, trolox succinate, and α-tocopheryl succinate conjugates with nitroxides by Zakharova, Ol’ga D., Frolova, Tat’yana S., Yushkova, Yuliya V., Chernyak, Elena I., Pokrovsky, Andrei G., Pokrovsky, Mikhail A., Morozov, Sergei V., Sinitsina, Ol’ga I., Grigor’ev, Igor A., Nevinsky, Georgy A.

“…A possible ability of twelve new derivatives of known antioxidants trolox (TroH), trolox succinate (TroS), α-tocopheryl succinate (α-TOS) containing nitroxyl…”
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Dynamics of pH-sensitive nitroxide radicals in water adsorbed in ordered mesoporous molecular sieves by EPR Spectroscopy by Kovaleva, Elena G., Molochnikov, Leonid S., Golovkina, Elena L., Hartmann, Martin, A. Kirilyuk, Igor, A. Grigor’ev, Igor

“…[Display omitted] •pH-sensitive nitroxides (NR) were used to study mesoporous sieves (MMS).•There were observed the “fast” and “slow” motions of NR inside the…”
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Electron paramagnetic resonance monitoring of ischemia-induced myocardial oxygen depletion and acidosis in isolated rat hearts using soluble paramagnetic probes by Komarov, Denis A., Dhimitruka, Ilirian, Kirilyuk, Igor A., Trofimiov, Dmitrii G., Grigor'ev, Igor A., Zweier, Jay L., Khramtsov, Valery V.

“…A new low‐field electron paramagnetic resonance approach for noninvasive measurements of myocardial oxygen tension and tissue acidity was developed. The…”
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New Amino-Bisphosphonate Building Blocks in the Synthesis of Bisphosphonic Derivatives Based on Lead Compounds by Becker, Christina S., Chukanov, Nikita V., Grigor'ev, Igor A.

“…A facile procedure for the synthesis of new aminobisphosphonate building blocks has been developed. The latter were used in the preparation of conjugates with…”
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Synthesis, structure, antioxidant activity, and water solubility of trolox ion conjugates by Yushkova, Yuliya V., Chernyak, Elena I., Gatilov, Yuriy V., Vasil'ev, Vladimir G., Morozov, Sergey V., Grigor'ev, Igor A.

“…The interaction of trolox with ammonia, alkylamines of different classes, and amino derivatives of heterocyclic compounds, including nitroxyl radicals and…”
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Real-time monitoring of drug-induced changes in the stomach acidity of living rats using improved pH-sensitive nitroxides and low-field EPR techniques by Potapenko, Dmitrii I., Foster, Margaret A., Lurie, David J., Kirilyuk, Igor A., Hutchison, James M.S., Grigor’ev, Igor A., Bagryanskaya, Elena G., Khramtsov, Valery V.

“…New improved pH-sensitive nitroxides were applied for in vivo studies. An increased stability of the probes towards reduction was achieved by the introduction…”
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Deactivation of Excited States of Kynurenine Covalently Linked to Nitroxides by Tsentalovich, Yuri P., Yanshole, Vadim V., Polienko, Yuliya F., Morozov, Sergey V., Grigor'ev, Igor A.

“…Due to ability of stable nitroxides to interact with free radicals, they are used as antioxidants for therapeutic and research goals in biology and medicine. A…”
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Effect of Sterical Shielding on the Redox Properties of Imidazoline and Imidazolidine Nitroxides by Kirilyuk, Igor A, Bobko, Andrey A, Semenov, Sergey V, Komarov, Denis A, Irtegova, Irina G, Grigor’ev, Igor A, Bagryanskaya, Elena

“…The oxidant properties of the series of 2,2,5,5-tetraalkyl imidazoline and imidazolidine nitroxides were investigated. An increase in the number of bulky alkyl…”
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In vitro and in vivo measurement of pH and thiols by EPR-based techniques by Khramtsov, Valery V, Grigor'ev, Igor A, Foster, Margaret A, Lurie, David J

“…In vitro and in vivo measurements of pH and thiols provide critical information on physiology and pathophysiology of living organisms, particularly related to…”
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Site-Directed Electrostatic Measurements with a Thiol-Specific pH-Sensitive Nitroxide:  Differentiating Local pK and Polarity Effects by High-Field EPR by Smirnov, Alex I, Ruuge, Andres, Reznikov, Vladimir A, Voinov, Maxim A, Grigor'ev, Igor A

“…This communication describes the use of a methanethiosulfonate derivative of an imidazolidine nitroxide, methanethiosulfonic acid…”
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EPR study of electron transport in the cyanobacterium Synechocystis sp. PCC 6803: Oxygen-dependent interrelations between photosynthetic and respiratory electron transport chains by Trubitsin, Boris V., Ptushenko, Vasilii V., Koksharova, Olga A., Mamedov, Mahir D., Vitukhnovskaya, Liya A., Grigor'ev, Igor A., Semenov, Alexey Yu, Tikhonov, Alexander N.

“…In this work, we investigated electron transport processes in the cyanobacterium Synechocystis sp. PCC 6803, with a special emphasis focused on…”
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The Principle of Validity: A Methodological Imperative in Forensic Practice by Grigor'ev, Igor' A.

“…The author reflects on whether validity can be considered both a principle of law and a functional principle of forensic expert activity. Disclosing the…”
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Synthesis of 2,5-Bis(spirocyclohexane)-Substituted Nitroxides of Pyrroline and Pyrrolidine Series, Including Thiol-Specific Spin Label: An Analogue of MTSSL with Long Relaxation Time by Kirilyuk, Igor A, Polienko, Yuliya F, Krumkacheva, Olesya A, Strizhakov, Rodion K, Gatilov, Yurii V, Grigor’ev, Igor A, Bagryanskaya, Elena G

“…The nitroxides of 7-azadispiro[5.1.5.2]pentadecane and 7-azadispiro[5.1.5.2]pentadeca-14-ene series have been prepared, including thiol-specific methane…”
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PHILOSOPHICAL AND THEORETICAL FOUNDATIONS OF THE PRINCIPLE OF VALIDITY IN FORENSIC PRACTICE by Grigor'ev, Igor' A.

“…The author reflects on the philosophical problem of reliability of expert knowledge, not only as a procedural attribute of judicial proceedings, but primarily…”
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Direct Measurement of H+ Activity inside Cross-Linked Functional Polymers Using Nitroxide Spin Probes by Molochnikov, Leonid S, Kovalyova, Elena G, Grigor'ev, Igor A, Zagorodni, Andrei A

“…The lack of a direct method for measuring activity inside ion-exchange resins was the main obstacle for strict thermodynamic investigations of such objects…”
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