Search Results - "Grigolon, Giovanna"

Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan by Grigolon, Giovanna, Araldi, Elisa, Erni, Reto, Wu, Jia Yee, Thomas, Carolin, La Fortezza, Marco, Laube, Beate, Pöhlmann, Doris, Stoffel, Markus, Zarse, Kim, Carreira, Erick M., Ristow, Michael, Fischer, Fabian

“…Aging is impacted by interventions across species, often converging on metabolic pathways. Transcription factors regulate longevity yet approaches for their…”
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From Coffee Waste to Active Ingredient for Cosmetic Applications by Grigolon, Giovanna, Nowak, Kathrin, Poigny, Stéphane, Hubert, Jane, Kotland, Alexis, Waldschütz, Laura, Wandrey, Franziska

“…Coffee silverskin (CS) is the thin epidermis covering and protecting the coffee bean and it represents the main by-product of the coffee roasting process. CS…”
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A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging by Thomas, Carolin, Erni, Reto, Wu, Jia Yee, Fischer, Fabian, Lamers, Greta, Grigolon, Giovanna, Mitchell, Sarah J., Zarse, Kim, Carreira, Erick M., Ristow, Michael

“…To ameliorate or even prevent signatures of aging in ultimately humans, we here report the identification of a previously undescribed polyacetylene contained…”
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Timut Pepper Extract Slows Age-Dependent Decline of Mobility and Collagen Loss and Promotes Longevity by Jongsma, Elisabeth, Grigolon, Giovanna, Baumann, Julia, Weinkove, David, Ewald, Collin Y, Wandrey, Franziska, Grothe, Torsten

“…Investigations into human longevity are increasingly focusing on healthspan enhancement, not just lifespan extension. Lifestyle modifications and nutritional…”
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Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A by Rozanov, Leonid, Ravichandran, Meenakshi, Grigolon, Giovanna, Zanellati, Maria Clara, Mansfeld, Johannes, Zarse, Kim, Barzilai, Nir, Atzmon, Gil, Fischer, Fabian, Ristow, Michael

“…Physiological aging is a complex process, influenced by a plethora of genetic and environmental factors. While being far from fully understood, a number of…”
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DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis by La Fortezza, Marco, Grigolon, Giovanna, Cosolo, Andrea, Pindyurin, Alexey, Breimann, Laura, Blum, Helmut, van Steensel, Bas, Classen, Anne-Kathrin

“…Tracking dynamic protein-chromatin interactions in vivo is key to unravel transcriptional and epigenetic transitions in development and disease. However,…”
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Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis by La Fortezza, Marco, Grigolon, Giovanna, Cosolo, Andrea, Pindyurin, Alexey, Breimann, Laura, Blum, Helmut, van Steensel, Bas, Classen, Anne-Kathrin

“…Unfortunately, the original version of this article contained a typographical error in one of the author names. The name of the author Alexey Pindyurin was…”
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Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection by Fischer, Fabian, Grigolon, Giovanna, Benner, Christoph, Ristow, Michael

“…Aging is the single largest risk factor for many debilitating conditions, including heart diseases, stroke, cancer, diabetes, and neurodegenerative disorders…”
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Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis by Ravichandran, Meenakshi, Priebe, Steffen, Grigolon, Giovanna, Rozanov, Leonid, Groth, Marco, Laube, Beate, Guthke, Reinhard, Platzer, Matthias, Zarse, Kim, Ristow, Michael

“…Whether and how regulation of genes and pathways contributes to physiological aging is topic of intense scientific debate. By performing an RNA…”
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Ingestion of single guide RNAs induces gene overexpression and extends lifespan in Caenorhabditis elegans via CRISPR activation by Fischer, Fabian, Benner, Christoph, Goyala, Anita, Grigolon, Giovanna, Vitiello, Davide, Wu, JiaYee, Zarse, Kim, Ewald, Collin Y., Ristow, Michael

“…Inhibition of gene expression in Caenorhabditis elegans, a versatile model organism for studying the genetics of development and aging, is achievable by…”
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