Search Results - "Grigg, C."

G-quadruplex structures formed by expanded hexanucleotide repeat RNA and DNA from the neurodegenerative disease-linked C9orf72 gene efficiently sequester and activate heme by Grigg, Jason C, Shumayrikh, Nisreen, Sen, Dipankar

“…The expansion of a (G(4)C(2))n repeat within the human C9orf72 gene has been causally linked to a number of neurodegenerative diseases, most notably familial…”
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Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA by Grigg, Jason C., Ke, Ailong

“…T box riboswitches are cis-acting RNA elements that bind to tRNA and sense its aminoacylation state to influence gene expression. Here, we present the 3.2 Å…”
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Epigenetic modification of cytosines fine tunes the stability of i-motif DNA by Wright, Elisé P, Abdelhamid, Mahmoud A S, Ehiabor, Michelle O, Grigg, Melanie C, Irving, Kelly, Smith, Nicole M, Waller, Zoë A E

“…i-Motifs are widely used in nanotechnology, play a part in gene regulation and have been detected in human nuclei. As these structures are composed of…”
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Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide by Kaiser, Julienne C, King, Alyssa N, Grigg, Jason C, Sheldon, Jessica R, Edgell, David R, Murphy, Michael E P, Brinsmade, Shaun R, Heinrichs, David E

“…Staphylococcus aureus requires branched-chain amino acids (BCAAs; isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acid synthesis, and…”
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T box RNA decodes both the information content and geometry of tRNA to affect gene expression by Grigg, Jason C., Chen, Yujie, Grundy, Frank J., Henkin, Tina M., Pollack, Lois, Ke, Ailong

“…The T box leader sequence is an RNA element that controls gene expression by binding directly to a specific tRNA and sensing its aminoacylation state. This…”
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Bacterial catabolism of acetovanillone, a lignin-derived compound by Dexter, Gara N., Navas, Laura E., Grigg, Jason C., Bajwa, Harbir, Levy-Booth, David J., Liu, Jie, Louie, Nathan A., Nasseri, Seyed A., Jang, Soo-Kyeong, Renneckar, Scott, Eltis, Lindsay D., Mohn, William W.

“…Bacterial catabolic pathways have considerable potential as industrial biocatalysts for the valorization of lignin, a major component of plant-derived biomass…”
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Characterization of Dye-Decolorizing Peroxidases from Rhodococcus jostii RHA1 by Roberts, Joseph N, Singh, Rahul, Grigg, Jason C, Murphy, Michael E. P, Bugg, Timothy D. H, Eltis, Lindsay D

“…The soil bacterium Rhodococcus jostii RHA1 contains two dye-decolorizing peroxidases (DyPs) named according to the subfamily they represent: DypA, predicted to…”
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Structural biology of heme binding in the Staphylococcus aureus Isd system by Grigg, Jason C., Ukpabi, Georgia, Gaudin, Catherine F.M., Murphy, Michael E.P.

“…Iron is an absolute requirement for nearly all organisms, but most bacterial pathogens are faced with extreme iron-restriction within their host environments…”
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Impacts of Preharvest Factors During Kernel Development on Rice Quality and Functionality by Siebenmorgen, Terry J, Grigg, Brandon C, Lanning, Sarah B

“…Rice quality and functionality are characterized in many ways, depending largely on the industry segment using the rice. These characteristics include…”
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Common themes and differences in SAM recognition among SAM riboswitches by Price, Ian R., Grigg, Jason C., Ke, Ailong

“…The recent discovery of short cis-acting RNA elements termed riboswitches has caused a paradigm shift in our understanding of genetic regulatory mechanisms…”
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tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch by Grigg, Jason C., Price, Ian R., Ke, Ailong

“…RNAs are prone to misfolding and are often more challenging to crystallize and phase than proteins. Here, we demonstrate that tRNA fusion can streamline the…”
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Unique Heme-Iron Coordination by the Hemoglobin Receptor IsdB of Staphylococcus aureus by Gaudin, Catherine F. M, Grigg, Jason C, Arrieta, Angelé L, Murphy, Michael E. P

“…Iron is an essential requirement for life for nearly all organisms. The human pathogen Staphylococcus aureus is able to acquire iron from the heme cofactor of…”
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Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus by Beasley, Federico C, Vinés, Enrique D, Grigg, Jason C, Zheng, Qin, Liu, Suya, Lajoie, Gilles A, Murphy, Michael E.P, Heinrichs, David E

“…Iron is critical for virtually all forms of life. The production of high-affinity iron chelators, siderophores, and the subsequent uptake of iron-siderophore…”
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Satellite tracking reveals long distance coastal travel and homing by translocated estuarine crocodiles, Crocodylus porosus by Read, Mark A, Grigg, Gordon C, Irwin, Steve R, Shanahan, Danielle, Franklin, Craig E

“…Crocodilians have a wide distribution, often in remote areas, are cryptic, secretive and are easily disturbed by human presence. Their capacity for large scale…”
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Haem recognition by a Staphylococcus aureus NEAT domain by Grigg, Jason C, Vermeiren, Christie L, Heinrichs, David E, Murphy, Michael E.P

“…Successful pathogenic organisms have developed mechanisms to thrive under extreme levels of iron restriction. Haem-iron represents the largest iron reservoir…”
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OP13.01: Mid‐trimester estimated fetal weight centile predicts later adverse perinatal outcomes, including at term by MacDonald, T. M., Jamieson‐Grigg, C., Tong, S., Walker, S. P.

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OP05.03: Slowing growth velocity as an indicator of fetal growth restriction in appropriate‐for‐gestational‐age fetuses by MacDonald, T. M., Jamieson‐Grigg, C., Kalinowski, P., Tong, S., Walker, S. P.

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The Evolution of Endothermy and Its Diversity in Mammals and Birds by Grigg, Gordon C., Beard, Lyn A., Augee, Michael L.

“…Many elements of mammalian and avian thermoregulatory mechanisms are present in reptiles, and the changes involved in the transition to endothermy are more…”
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The IEEE Reliability Test System-1996. A report prepared by the Reliability Test System Task Force of the Application of Probability Methods Subcommittee by Grigg, C., Wong, P., Albrecht, P., Allan, R., Bhavaraju, M., Billinton, R., Chen, Q., Fong, C., Haddad, S., Kuruganty, S., Li, W., Mukerji, R., Patton, D., Rau, N., Reppen, D., Schneider, A., Shahidehpour, M., Singh, C.

“…This report describes an enhanced test system (RTS-96) for use in bulk power system reliability evaluation studies. The value of the test system is that it…”
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Heme Coordination by Staphylococcus aureus IsdE by Grigg, Jason C., Vermeiren, Christie L., Heinrichs, David E., Murphy, Michael E.P.

“…Staphylococcus aureus is a Gram-positive bacterial pathogen and a leading cause of hospital acquired infections. Because the free iron concentration in the…”
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