Search Results - "Griffiths, Shawn E."
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Expansion and contraction of the umbrella cell apical junctional ring in response to bladder filling and voiding
Published in Molecular biology of the cell (22-07-2019)“…The epithelial junctional complex, composed of tight junctions, adherens junctions, desmosomes, and an associated actomyosin cytoskeleton, forms the apical…”
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WNK kinases sense molecular crowding and rescue cell volume via phase separation
Published in Cell (23-11-2022)“…When challenged by hypertonicity, dehydrated cells must recover their volume to survive. This process requires the phosphorylation-dependent regulation of…”
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Effects of extreme potassium stress on blood pressure and renal tubular sodium transport
Published in American journal of physiology. Renal physiology (01-06-2020)“…We characterized mouse blood pressure and ion transport in the setting of commonly used rodent diets that drive K intake to the extremes of deficiency and…”
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Kidney-Specific WNK1 Amplifies NCC Responsiveness to Potassium Imbalance: PO1085
Published in Journal of the American Society of Nephrology (01-10-2021)Get full text
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WNK1 Regulates Cell Volume via Crowding‐Induced Phase Transitions
Published in The FASEB journal (01-04-2020)“…Abstract only When challenged by hypertonicity, dehydrated cells recover their volume though regulatory volume increase (RVI). This process is thought to be…”
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