Search Results - "Griffiths, L.R"

Association study of the calcitonin gene-related polypeptide-alpha (CALCA) and the receptor activity modifying 1 (RAMP1) genes with migraine by Sutherland, H.G., Buteri, J., Menon, S., Haupt, L.M., MacGregor, E.A., Lea, R.A., Griffiths, L.R.

“…Migraine is a common neurovascular brain disorder characterised by recurrent attacks of severe headache that may be accompanied by various neurological…”
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Analysis of 3 common polymorphisms in the KCNK18 gene in an Australian Migraine Case-control cohort by Maher, B.H., Taylor, M., Stuart, S., Okolicsanyi, R.K., Roy, B., Sutherland, H.G., Haupt, L.M., Griffiths, L.R.

“…Migraine is a common neurological disorder characterised by temporary disabling attacks of severe head pain and associated disturbances. There is significant…”
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Semaphorin–plexin signalling genes associated with human breast tumourigenesis by Gabrovska, P.N., Smith, R.A., Tiang, T., Weinstein, S.R., Haupt, L.M., Griffiths, L.R.

“…Gene expression profiling has enabled us to demonstrate the heterogeneity of breast cancers. The potential of a tumour to grow and metastasise is partly…”
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Role of the apolipoprotein E and catechol-O-methyltransferase genes in prospective and retrospective memory traits by Dongés, B., Haupt, L.M., Lea, R.A., Chan, R.C.K., Shum, D.H.K., Griffiths, L.R.

“…Human memory is a complex neurocognitive process. By combining psychological and molecular genetics expertise, we examined the APOE ε4 allele, a known risk…”
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A molecular genetic approach for forensic animal species identification by Bellis, C., Ashton, K.J., Freney, L., Blair, B., Griffiths, L.R.

“…This study investigated potential markers within chromosomal, mitochondrial DNA (mtDNA) and ribosomal RNA (rRNA) with the aim of developing a DNA based method…”
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Association study of calcitonin gene-related polypeptide-alpha (CALCA) gene polymorphism with migraine by Menon, S, Buteri, J, Roy, B, Murrell, M, Quinlan, S, MacMillan, J.C, Lea, R.A, Haupt, L.M, Griffiths, L.R

“…Abstract Migraine is a neurological disorder that is associated with increased levels of calcitonin gene-related peptide (CGRP) in plasma. CGRP, being one of…”
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Investigation of the 1758G > C and 2880A > G variants within the NCOA3 gene in a breast cancer affected Australian population by Gabrovska, P.N., Smith, R.A., O'Leary, G., Haupt, L.M., Griffiths, L.R.

“…NCOA3 is a known low to moderate-risk breast cancer susceptibility gene, amplified in 5–10% and over expressed in about 60% of breast tumours. Additionally,…”
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No association between MTHFR A1298C and MTRR A66G polymorphisms, and MS in an Australian cohort by Szvetko, A.L, Fowdar, J, Nelson, J, Colson, N, Tajouri, L, Csurhes, P.A, Pender, M.P, Griffiths, L.R

“…Abstract Multiple sclerosis (MS) is a complex neurological disease that affects the central nervous system (CNS) resulting in debilitating neuropathology…”
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Modulation of in vitro platelet 5-HT release by species of Erythrina and Cymbopogon by Rogers, K.L., Grice, I.D., Griffiths, L.R.

“…Extracts of Australian plants were screened to detect constituents affecting adenosine di-phosphate (ADP) induced platelet aggregation and […”
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Clinical and genetic spectrum of SCN2A-associated episodic ataxia by Schwarz, N., Bast, T., Gaily, E., Golla, G., Gorman, K.M., Griffiths, L.R., Hahn, A., Hukin, J., King, M., Korff, C., Miranda, M.J., Møller, R.S., Neubauer, B., Smith, R.A., Smol, T., Striano, P., Stroud, B., Vaccarezza, M., Kluger, G., Lerche, H., Fazeli, W.

“…Pathogenic variants in SCN2A are associated with various neurological disorders including epilepsy, autism spectrum disorder and intellectual disability. Few…”
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Investigating the influence of mtDNA and nuclear encoded mitochondrial variants on high intensity interval training outcomes by Harvey, N. R., Voisin, S., Lea, R. A., Yan, X., Benton, M. C., Papadimitriou, I. D., Jacques, M., Haupt, L. M., Ashton, K. J., Eynon, N., Griffiths, L. R.

“…Mitochondria supply intracellular energy requirements during exercise. Specific mitochondrial haplogroups and mitochondrial genetic variants have been…”
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Signaling pathway genes for blood pressure, folate and cholesterol levels among hypertensives: an epistasis analysis by Wei, L K, Menon, S, Griffiths, L R, Gan, S H

“…Irregular atrial pressure, defective folate and cholesterol metabolism contribute to the pathogenesis of hypertension. However, little is known about the…”
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Common polygenic variation contributes to risk of migraine in the Norfolk Island population by Rodriguez-Acevedo, A. J., Ferreira, M. A., Benton, Miles C., Carless, Melanie A., Goring, Harald H., Curran, Joanne E., Blangero, John, Lea, R. A., Griffiths, L. R.

“…Migraine has been defined as a common disabling primary headache disorder. Epidemiology studies have provided with the undeniable evidence of genetic…”
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β-Actin—an unsuitable internal control for RT-PCR by Selvey, S., Thompson, E.W., Matthaei, K., Lea, R.A., Irving, M.G., Griffiths, L.R.

“…Despite reports confirming cell-cycle dependent gene expression and a number of studies describing specific circumstances in which β-actin is also regulated,…”
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Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura by Fernandez, F., Lea, R.A., Colson, N.J., Bellis, C., Quinlan, S., Griffiths, L.R.

“…Migraine is a debilitating neurological disorder, affecting 12% of Caucasian populations. It is well known that migraine has a strong genetic component,…”
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Polymorphisms of the VDR gene are associated with presence of solar keratoses on the skin by Carless, M.A., Kraska, T., Lintell, N., Neale, R.E., Green, A.C., Griffiths, L.R.

“…Summary Background  Vitamin D has a range of biological effects including antiproliferative functions that are mediated through its receptors, encoded by the…”
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A novel immunodeficiency disorder characterized by genetic amplification of interleukin 25 by Green, M R, Camilleri, E, Gandhi, M K, Peake, J, Griffiths, L R

“…Many primary immunodeficiency disorders of differing etiologies have been well characterized, and much understanding of immunological processes has been gained…”
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Linkage mapping of CVD risk traits in the isolated Norfolk Island population by Bellis, C, Cox, H. C, Dyer, T. D, Charlesworth, J. C, Begley, K. N, Quinlan, S, Lea, R. A, Heath, S. C, Blangero, J, Griffiths, L. R

“…To understand the underlying genetic architecture of cardiovascular disease (CVD) risk traits, we undertook a genome-wide linkage scan to identify CVD…”
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Migraine genetics and prospects for pharmacotherapy by Colson, N.J., Fernandez, F., Griffiths, L.R.

“…Migraine is a common complex neurological disorder with a well‐known but poorly characterized genetic liability. The search for migraine susceptibility genes…”
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Fluorescence detection of plant extracts that affect neuronal voltage-gated Ca 2+ channels by Rogers, K.L., Fong, W.F., Redburn, J., Griffiths, L.R.

“…Structurally novel compounds able to block voltage-gated Ca 2+ channels (VGCCs) are currently being sought for the development of new drugs directed at…”
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