Search Results - "Griffiths, E. A"

Cyclosporin A and cardioprotection: from investigative tool to therapeutic agent by Hausenloy, DJ, Boston‐Griffiths, EA, Yellon, DM

“…Ischaemic heart disease (IHD) is the leading cause of death and disability worldwide. The pathophysiological effects of IHD on the heart most often result from…”
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The learning curve to achieve satisfactory completion rates in upper GI endoscopy: an analysis of a national training database by Ward, S T, Hancox, A, Mohammed, M A, Ismail, T, Griffiths, E A, Valori, R, Dunckley, P

“…The aim of this study was to determine the number of OGDs (oesophago-gastro-duodenoscopies) trainees need to perform to acquire competency in terms of…”
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Defining true impact of anastomotic leaks after oesophagogastric cancer surgery by Kamarajah, S. K., Griffiths, E. A, Phillips, A. W.

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Minimally invasive techniques for transthoracic oesophagectomy for oesophageal cancer: systematic review and network meta‐analysis by Siaw‐Acheampong, K., Kamarajah, S. K., Gujjuri, R., Bundred, J. R., Singh, P., Griffiths, E. A.

“…Background Oesophagectomy is a demanding operation that can be performed by different approaches including open surgery or a combination of minimal access…”
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A Modified AUGIS Delphi Process to Establish Future Research Priorities in Benign Upper Gastrointestinal Surgery by Wilson, Michael S. J., Vaughan-Shaw, P., Boyle, C., Yong, G. L., Oglesby, S., Skipworth, R., Lamb, P., Griffiths, E. A. T., Attwood, S. E. A.

“…Background The aim of our study was to use a modified Delphi process to determine the research priorities amongst benign upper gastrointestinal (UGI) surgeons…”
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Impact of postoperative complications on survival after oesophagectomy for oesophageal cancer by Bundred, J. R., Hollis, A. C., Evans, R., Hodson, J., Whiting, J. L., Griffiths, E. A.

“…Background Recent evidence suggests that complications after oesophagectomy may decrease short‐ and long‐term survival of patients with oesophageal cancer…”
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Anastomotic techniques for oesophagectomy for malignancy: systematic review and network meta‐analysis by Kamarajah, S. K., Bundred, J. R., Singh, P., Pasquali, S., Griffiths, E. A.

“…Background Current evidence on the benefits of different anastomotic techniques (hand‐sewn (HS), circular stapled (CS), triangulating stapled (TS) or linear…”
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A preoperative predictive tool to assess the need for staging laparoscopy in oesophagogastric cancer patients by Halle-Smith, J M, Bage, T, Kamarajah, S K, Siddaiah-Subramanya, M, Pande, R, Whiting, J L, Griffiths, E A

“…Staging laparoscopy (SL) has become commonplace in the preoperative staging pathway for oesophagogastric (OG) cancer. SL is often performed before curative…”
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Oesophagopleural fistula after pneumonectomy: A systematic review and case series by Phelan, L, Layton, G R, Lee, E H, Halle-Smith, J, Bishay, E, Griffiths, E A

“…There is a paucity of data on the optimal management of oesophagopleural fistula (OPF) following pneumonectomy. The current published literature is limited to…”
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Urgent surgical repair of symptomatic Bochdalek hernia containing an intrathoracic kidney by Halle-Smith, J M, Pande, R, Griffiths, E A

“…Bochdalek hernias rarely contain an intrathoracic kidney, and there are few reports of their operative repair. A woman presented with progressive dyspnoea…”
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Meta‐analysis of the influence of a positive circumferential resection margin in oesophageal cancer by Evans, R., Bundred, J. R., Kaur, P., Hodson, J., Griffiths, E. A.

“…Background The evidence regarding the prognostic impact of a positive circumferential resection margin (CRM) in oesophageal cancer is conflicting, and there is…”
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Stabilizing interactions between D666‐S1787 and T657‐Y1792 at the A2‐A3 interface support factor VIIIa stability in the blood clotting pathway by Monaghan, M., Wakabayashi, H., Griffiths, A. E., Fay, P. J.

“…Essentials Factor VIIIa (FVIIIa) is unstable due to loss of A2; D666 and Y1792 contribute to its stability. We conducted a study to identify the interactions…”
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Radial forearm free flap as the last resort for oesophageal reconstruction by Griffiths, E A, Iqbal, N, Martin, T, Ranasinghe, A, Parmar, S

“…Strategies for oesophageal reconstruction following resection vary according to the nature of the pathology encountered, patient factors and surgeon…”
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Is the hypoxia-inducible factor pathway important in gastric cancer? by Griffiths, E.A., Pritchard, S.A., Welch, I.M., Price, P.M., West, C.M.

“…Tumour hypoxia is well recognised in oncology to be a key factor resulting in treatment resistance and poor prognosis. Hypoxia leads to the expression of a…”
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Current practice of antibiotic prophylaxis during elective laparoscopic cholecystectomy by Macano, Caw, Griffiths, E A, Vohra, R S

“…INTRODUCTION Current guidelines do not recommend antibiotic prophylaxis in elective laparoscopic cholecystectomy. Despite this, there is wide variation in…”
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Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence by Griffiths, E A, Pritchard, S A, McGrath, S M, Valentine, H R, Price, P M, Welch, I M, West, C M L

“…Hypoxia-associated markers are involved in the progression of several malignancies, but are relatively unstudied in Barrett's carcinogenesis. Our aim was to…”
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Hypoxia-associated markers in gastric carcinogenesis and HIF-2α in gastric and gastro-oesophageal cancer prognosis by Griffiths, E A, Pritchard, S A, McGrath, S M, Valentine, H R, Price, P M, Welch, I M, West, C M L

“…The study investigated hypoxia-associated markers (HIF-2 α , Epo, Epo-R, Glut-1 and VEGF) along with Ki-67 in a gastric carcinogenesis model, and the…”
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COVID-19 vaccination and breakthrough infections in patients with cancer by Schmidt, A.L., Labaki, C., Hsu, C.-Y., Bakouny, Z., Balanchivadze, N., Berg, S.A., Blau, S., Daher, A., El Zarif, T., Friese, C.R., Griffiths, E.A., Hawley, J.E., Hayes-Lattin, B., Karivedu, V., Latif, T., Mavromatis, B.H., McKay, R.R., Nagaraj, G., Nguyen, R.H., Panagiotou, O.A., Portuguese, A.J., Puc, M., Santos Dutra, M., Schroeder, B.A., Thakkar, A., Wulff-Burchfield, E.M., Mishra, S., Farmakiotis, D., Shyr, Yu, Warner, J.L., Choueiri, T.K., Choueiri, T.K., Duma, N., Farmakiotis, D., Grivas, P., de Lima Lopes, G., Painter, C.A., Peters, S., Rini, B.I., Shah, D.P., Thompson, M.A., Warner, J.L.

“…Vaccination is an important preventive health measure to protect against symptomatic and severe COVID-19. Impaired immunity secondary to an underlying…”
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Meta-analysis of perioperative antibiotics in patients undergoing laparoscopic cholecystectomy by Pasquali, S., Boal, M., Griffiths, E. A., Alderson, D., Vohra, R. S.

“…Background The effectiveness of perioperative antibiotics in reducing surgical‐site infection (SSI) and overall nosocomial infections in patients undergoing…”
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Machine learning to predict early recurrence after oesophageal cancer surgery by Rahman, S. A., Walker, R. C., Lloyd, M. A., Grace, B. L., van Boxel, G. I., Kingma, B. F., Ruurda, J. P., van Hillegersberg, R., Harris, S., Parsons, S., Mercer, S., Griffiths, E. A., O'Neill, J. R., Turkington, R., Fitzgerald, R. C., Underwood, T. J., Noorani, Ayesha, Elliott, Rachael Fels, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Crawte, Jason, Chettouh, Hamza, Contino, Gianmarco, Li, Xiaodun, Gregson, Eleanor, Zeki, Sebastian, de la Rue, Rachel, Malhotra, Shalini, Tavaré, Simon, Lynch, Andy G., Smith, Mike L., Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O'Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Byrne, James P., Kelly, Jamie J., Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Chang, Andrew Davies Fuju, Zylstra, Janine, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Shamila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna

“…Background Early cancer recurrence after oesophagectomy is a common problem, with an incidence of 20–30 per cent despite the widespread use of neoadjuvant…”
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