Search Results - "Griffiths, Belinda"

Mouse Telocentric Sequences Reveal a High Rate of Homogenization and Possible Role in Robertsonian Translocation by Kalitsis, Paul, Griffiths, Belinda, Choo, K. H. Andy

“…The telomere and centromere are two specialized structures of eukaryotic chromosomes that are essential for chromosome stability and segregation. These…”
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Construction of Neocentromere-Based Human Minichromosomes by Telomere-Associated Chromosomal Truncation by Saffery, Richard, Wong, Lee H., Irvine, Danielle V., Bateman, Melissa A., Griffiths, Belinda, Cutts, Suzanne M., Cancilla, Michael R., Cendron, Angela C., Stafford, Angela J., K. H. Andy Choo

“…Neocentromeres (NCs) are fully functional centromeres that arise ectopically in noncentromeric regions lacking α-satellite DNA. Using telomere-associated…”
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Components of the human spindle checkpoint control mechanism localize specifically to the active centromere on dicentric chromosomes by SAFFERY, Richard, IRVINE, Danielle V, GRIFFITHS, Belinda, KALITSIS, Paul, CHOO, K. H

“…The spindle checkpoint control mechanism functions to ensure faithful chromosome segregation by delaying cell division until all chromosomes are correctly…”
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Obituaries: John Lawson Griffiths by Griffiths, Belinda

“…John was in general practice in Pen-coed, south Wales, until his retirement, aged 70. In 1957, while still working his general practice rota, he went into…”
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Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice by Kalitsis, Paul, Fowler, Kerry J., Griffiths, Belinda, Earle, Elizabeth, Chow, C. W., Jamsen, Kris, Choo, K. H. Andy

“…Mitotic spindle checkpoint proteins have been shown to play a crucial role in the accurate segregation of chromosomes during cell division. Bub3 is a member of…”
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Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins by SAFFERY, R, IRVINE, D. V, GRIFFITHS, B, KALITSIS, P, WORDEMAN, L, CHOO, K. H. A

“…Using combined immunofluorescence and fluorescence in situ hybridization (FISH) analysis we have extensively characterized the proteins associating with two…”
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John Lawson Griffiths by Griffiths, Belinda

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Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis by Kalitsis, Paul, Fowler, Kerry J, Earle, Elizabeth, Griffiths, Belinda, Howman, Emily, Newson, Ainsley J, Choo, K H Andy

“…CENP-A is an essential histone H3-like protein that localizes to the centromeric region of eukaryotic chromosomes. Heterozygous and homozygous Cenpa-GFP…”
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Uterine expression of alternatively spliced mRNAs of mouse splicing factor SC35 during early pregnancy by Nie, Gui-Ying, Li, Ying, Batten, Leigh, Griffiths, Belinda, Wang, Jian, Findlay, Jock K., Salamonsen, Lois A.

“…RNA differential display was applied to identify genes critical for the establishment of pregnancy in the mouse. One of the gene fragments identified was…”
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