Search Results - "Griffith, David M"

Early lactate clearance in septic patients with elevated lactate levels admitted from the emergency department to intensive care: Time to aim higher? by Walker, Craig A., MB, ChB, FCEM, Griffith, David M., MB, ChB, FRCA, Gray, Alasdair J., MB, ChB, MD, FRCS, FCEM, Datta, Deepankar, MB, ChB, BSc(Hons), Hay, Alasdair W., MB, ChB, FRCA, DICM, MSc

“…Abstract Purpose Septic patients with hyperlactatemia have increased mortality rates, irrespective of hemodynamic and oxygen-derived variables. The aims of the…”
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Persistent inflammation and recovery after intensive care: A systematic review by Griffith, David M., MD, Vale, Matthew E., MBBS, Campbell, Christine, PhD, Lewis, Steff, PhD, Walsh, Timothy S., MD

“…Abstract Purpose Physical weakness is common after critical illness; however, it is not clear how best to treat it. Inflammation characterizes critical…”
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Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol by Jones, Jennifer R A, Berney, Sue, Berry, Michael J, Files, D Clark, Griffith, David M, McDonald, Luke A, Morris, Peter E, Moss, Marc, Nordon-Craft, Amy, Walsh, Timothy, Gordon, Ian, Karahalios, Amalia, Puthucheary, Zudin, Denehy, Linda

“…IntroductionThe number of inconclusive physical rehabilitation randomised controlled trials for patients with critical illness is increasing. Evidence suggests…”
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Body Composition After Critical Illness: Fat in All the Wrong Places? by Griffith, David M.

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Regional anaesthesia for knee arthroplasty in the UK: survey of practice by Findlay, Georgina, Chillingworth, Simon, Semple, David, Clement, Nicholas D., Griffith, David M.

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Increased Hospital-Based Physical Rehabilitation and Information Provision After Intensive Care Unit Discharge: The RECOVER Randomized Clinical Trial by Walsh, Timothy S, Salisbury, Lisa G, Merriweather, Judith L, Boyd, Julia A, Griffith, David M, Huby, Guro, Kean, Susanne, Mackenzie, Simon J, Krishan, Ashma, Lewis, Stephanie C, Murray, Gordon D, Forbes, John F, Smith, Joel, Rattray, Janice E, Hull, Alastair M, Ramsay, Pamela

“…Critical illness results in disability and reduced health-related quality of life (HRQOL), but the optimum timing and components of rehabilitation are…”
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Outcomes from COVID-19 Clinical Trials in Hospitalized Patients: Seeking the Truth That Matters by Griffith, David M, Walsh, Timothy S

“…Griffith and Walsh discuss the study of Douin and colleagues, in which they highlight the potential pitfalls of using hospital discharge as an endpoint in…”
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Socioeconomic Position and Health Outcomes Following Critical Illness: A Systematic Review by Jones, Jennifer R. A., Berney, Sue, Connolly, Bronwen, Waterland, Jamie L., Denehy, Linda, Griffith, David M., Puthucheary, Zudin A.

“…OBJECTIVES:Systematically review evidence examining association between preadmission socioeconomic position and physical function, health-related quality of…”
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Comparison of Unyvero P55 Pneumonia Cartridge, in-house PCR and culture for the identification of respiratory pathogens and antibiotic resistance in bronchoalveolar lavage fluids in the critical care setting by Gadsby, Naomi J., McHugh, Martin P., Forbes, Callum, MacKenzie, Laura, Hamilton, Stephen K. D., Griffith, David M., Templeton, Kate E.

“…Faster respiratory pathogen detection and antibiotic resistance identification are important in critical care due to the severity of illness, significant prior…”
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Appetite during the recovery phase of critical illness: a cohort study by Merriweather, Judith L, Griffith, David M, Walsh, Timothy S

“…Background/Objectives Reduced appetite is a recognised physiological symptom in survivors of critical illness. While reduced appetite has been reported by…”
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Pharmacological Therapy for the Prevention and Treatment of Weakness After Critical Illness: A Systematic Review by Shepherd, Stephen J., Newman, Richard, Brett, Stephen J., Griffith, David M.

“…OBJECTIVES:ICU-acquired weakness is a common complication of critical illness and can have significant effects upon functional status and quality of life. As…”
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Determinants of Health-Related Quality of Life After ICU: Importance of Patient Demographics, Previous Comorbidity, and Severity of Illness by Griffith, David M., Salisbury, Lisa G., Lee, Robert J., Lone, Nazir, Merriweather, Judith L., Walsh, Timothy S.

“…OBJECTIVES:ICU survivors frequently report reduced health-related quality of life, but the relative importance of preillness versus acute illness factors in…”
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Responsiveness of Critically Ill Adults With Multimorbidity to Rehabilitation Interventions: A Patient-Level Meta-Analysis Using Individual Pooled Data From Four Randomized Trials by Jones, Jennifer R. A., Karahalios, Amalia, Puthucheary, Zudin A., Berry, Michael J., Files, D. Clark, Griffith, David M., McDonald, Luke A., Morris, Peter E., Moss, Marc, Nordon-Craft, Amy, Walsh, Timothy, Berney, Sue, Denehy, Linda

“…To explore if patient characteristics (pre-existing comorbidity, age, sex, and illness severity) modify the effect of physical rehabilitation (intervention vs…”
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Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation by Mirchandani, Ananda S., Jenkins, Stephen J., Bain, Calum C., Sanchez-Garcia, Manuel A., Lawson, Hannah, Coelho, Patricia, Murphy, Fiona, Griffith, David M., Zhang, Ailiang, Morrison, Tyler, Ly, Tony, Arienti, Simone, Sadiku, Pranvera, Watts, Emily R., Dickinson, Rebecca. S., Reyes, Leila, Cooper, George, Clark, Sarah, Lewis, David, Kelly, Van, Spanos, Christos, Musgrave, Kathryn M., Delaney, Liam, Harper, Isla, Scott, Jonathan, Parkinson, Nicholas J., Rostron, Anthony J., Baillie, J. Kenneth, Clohisey, Sara, Pridans, Clare, Campana, Lara, Lewis, Philip Starkey, Simpson, A. John, Dockrell, David H., Schwarze, Jürgen, Hirani, Nikhil, Ratcliffe, Peter J., Pugh, Christopher W., Kranc, Kamil, Forbes, Stuart J., Whyte, Moira K. B., Walmsley, Sarah R.

“…Hypoxemia is a defining feature of acute respiratory distress syndrome (ARDS), an often-fatal complication of pulmonary or systemic inflammation, yet the…”
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The 6 Ps of post-ICU recovery: application of a shared conceptual model by Jones, Jennifer R.A., Griffith, David M.

“…PURPOSE OF REVIEWWe aimed to explore, through a conceptual model, how we can maximize the post-ICU recovery of patients with ICU-acquired weakness (ICU-AW)…”
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Intravenous iron to treat anaemia following critical care: a multicentre feasibility randomised trial by Shah, Akshay, Chester-Jones, Mae, Dutton, Susan J, Marian, Ioana R, Barber, Vicki S, Griffith, David M, Singleton, Jo, Wray, Katherine, James, Tim, Drakesmith, Hal, Robbins, Peter A, Frise, Matthew C, Young, J Duncan, Walsh, Timothy S, McKechnie, Stuart R, Stanworth, Simon J

“…Anaemia is common and associated with poor outcomes in survivors of critical illness. However, the optimal treatment strategy is unclear. We conducted a…”
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Serum hepcidin potentially identifies iron deficiency in survivors of critical illness at the time of hospital discharge by Shah, Akshay, Wray, Katherine, James, Timothy, Shine, Brian, Morovat, Reza, Stanworth, Simon, McKechnie, Stuart, Kirkbride, Rachael, Griffith, David M., Walsh, Timothy S., Drakesmith, Hal, Roy, Noémi

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Systemic inflammation after critical illness: relationship with physical recovery and exploration of potential mechanisms by Griffith, David M, Lewis, Steff, Rossi, Adriano G, Rennie, Jillian, Salisbury, Lisa, Merriweather, Judith L, Templeton, Kate, Walsh, Timothy S

“…Physical recovery following critical illness is slow, often incomplete and is resistant to rehabilitation interventions. We aimed to explore the contribution…”
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Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta-analysis, and perspective of observational studies by Taylor, Rory, Zhang, Chengyuan, George, Deslit, Kotecha, Sarah, Abdelghaffar, Mariam, Forster, Thorsten, Santos Rodrigues, Patricia Dos, Reisinger, Alexander C., White, Daniel, Hamilton, Fergus, Watkins, W. John, Griffith, David M., Ghazal, Peter

“…Mechanistic studies have established a biological role of sterol metabolism in infection and immunity with clinical data linking deranged cholesterol…”
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Author Correction: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation by Mirchandani, Ananda S., Jenkins, Stephen J., Bain, Calum C., Sanchez-Garcia, Manuel A., Lawson, Hannah, Coelho, Patricia, Murphy, Fiona, Griffith, David M., Zhang, Ailiang, Morrison, Tyler, Ly, Tony, Arienti, Simone, Sadiku, Pranvera, Watts, Emily R., Dickinson, Rebecca. S., Reyes, Leila, Cooper, George, Clark, Sarah, Lewis, David, Kelly, Van, Spanos, Christos, Musgrave, Kathryn M., Delaney, Liam, Harper, Isla, Scott, Jonathan, Parkinson, Nicholas J., Rostron, Anthony J., Baillie, J. Kenneth, Clohisey, Sara, Pridans, Clare, Campana, Lara, Lewis, Philip Starkey, Simpson, A. John, Dockrell, David H., Schwarze, Jürgen, Hirani, Nikhil, Ratcliffe, Peter J., Pugh, Christopher W., Kranc, Kamil, Forbes, Stuart J., Whyte, Moira K. B., Walmsley, Sarah R.

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