Search Results - "Griffin, Johanna A."

Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region by Reaban, Mary E, Griffin, Johanna A

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Non-Sialate Inhibitor of Influenza A/WSN/33 Neuraminidase by Wu, Joe C, Peet, Gregory W, Coutts, Simon J, Eckner, Robert J, Griffin, Johanna A, Farina, Peter R

“…An N1 strain of influenza A virus neuraminidase (A/WSN/33 NA) was purified and used to screen for inhibitors. As a result, a well-known tuberculostatic,…”
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Transcription induces the formation of a stable RNA-DNA hybrid in the immunoglobulin alpha switch region by Reaban, ME, Lebowitz, J, Griffin, JA

“…We previously showed that the in vitro transcription of a negatively supercoiled plasmid containing the murine IgA switch region caused the formation of fewer…”
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Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region by REABAN, M. E, GRIFFIN, J. A

“…A deletion DNA rearrangement is associated with immunoglobulin class switching from IgM to IgG, IgA or IgE This recombination occurs in immunoglobulin switch…”
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Enterovirus Meningitis in Adults by Rotbart, Harley A., Brennan, P. J., Fife, Kenneth H., Romero, Jose R., Griffin, Johanna A., McKinlay, Mark A., Hayden, Frederick G.

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Chimeric Human Immunodeficiency Virus Type 1/Type 2 Reverse Transcriptases Display Reversed Sensitivity to Nonnucleoside Analog Inhibitors by Shih, Cheng-Kon, Rose, Janice M., Hansen, Gale L., Wu, Joe C., Bacolla, Albino, Griffin, Johanna A.

“…Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT), an important therapeutic target in the treatment of AIDS, is effectively inhibited by a…”
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Different pathways of differentiation of pre-B cell lines are induced by dendritic cells and T cells from different lymphoid tissues by Spalding, D M, Griffin, J A

“…Nontransformed pre-B cells were induced to differentiate in vitro along several different but predictable pathways with only dendritic cells (DC) and…”
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Amino acid substitutions in HIV-1 reverse transcriptase with corresponding residues from HIV-2. Effect on kinetic constants and inhibition by non-nucleoside analogs by Bacolla, A, Shih, C K, Rose, J M, Piras, G, Warren, T C, Grygon, C A, Ingraham, R H, Cousins, R C, Greenwood, D J, Richman, D

“…Nevirapine is a highly potent and specific inhibitor of human immunodeficiency virus type 1 (HIV-1) polymerase, but is inactive against HIV-2 and other…”
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Diversity in the germline antibody repertoire: molecular evolution of the T15 VH gene family by PERLMUTTER, R. M, BERSON, B, GRIFFIN, J. A, HOOD, L

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Effects of hexose starvation and the role of sialic acid in influenza virus release by Griffin, J A, Basak, S, Compans, R W

“…We previously reported that growth of influenza virus in the presence of cytochalasin B (CB), a drug that disrupts microfilaments and blocks hexose transport,…”
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Studies on the mechanism of phagocytosis. II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes by Griffin, Jr, F M, Griffin, J A, Silverstein, S C

“…We have examined the effect of the distribution of anti-immunoglobulin IgG molecules on the surface of bone marrow-derived lymphocytes upon the interaction of…”
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Augmentation of macrophage complement receptor function in vitro. I. Characterization of the cellular interactions required for the generation of a T-lymphocyte product that enhances macrophage complement receptor function by Griffin, J A, Griffin, Jr, F M

“…The function of complement receptors of mouse peritoneal macrophages was converted in vitro from mediating only attachment of macrophage complement receptor…”
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Immunoglobulin Gene Rearrangements and Deletions in Human Epstein-Barr Virus-Transformed Cell Lines Producing Different IgG and IgA Subclasses by Webb, Carol F., Cooper, Max D., Burrows, Peter D., Griffin, Johanna A.

“…During differentiation B lymphocytes may switch from the expression of surface IgM to the synthesis of IgG, IgA, or IgE isotypes by using a different heavy…”
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Pre-pre-B cells containing only cytoplasmic B220 can be induced by dendritic cells and T cells to differentiate in vitro by Saleh, F, Spalding, D M, Griffin, J A

“…We have derived from spleens of nude mice early B lineage cells that were phenotypically compatible with a pre-pre-B cell stage of differentiation. Although…”
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Effect of cytochalasin B on the maturation of enveloped viruses by Griffin, J A, Compans, R W

“…The maturation of two enveloped viruses, influenza and vesicular stomatitis, occurs in cells treated with cytochalasin B. Virions produced in the presence of…”
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Many different levels of maturation and commitment are present in nontransformed cells identified serologically as pre-B cells by Griffin, J A, Spalding, D M

“…The pre-B cell stage of B lymphocyte development is characterized by the presence of immunoglobulin heavy chains of the IgM isotype in the cytoplasm and no…”
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Recombinant DNA--potential for gene therapy by Griffin, J A

“…Certainly, if progress in recombinant DNA technology continues at its present rate, we have every reason to expect many more major breakthroughs in the…”
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