Search Results - "Griffin, Gail L"

Keratinocyte-targeted expression of human laminin γ2 rescues skin blistering and early lethality of laminin γ2 deficient mice by Adair-Kirk, Tracy L, Griffin, Gail L, Meyer, Michelle J, Kelley, Diane G, Miner, Jeffrey H, Keene, Douglas R, Marinkovich, M Peter, Ruppert, J Michael, Uitto, Jouni, Senior, Robert M

“…Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes,…”
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Clara cells impact the pulmonary innate immune response to LPS by Elizur, Arnon, Adair-Kirk, Tracy L, Kelley, Diane G, Griffin, Gail L, deMello, Daphne E, Senior, Robert M

“…Airway epithelial cells secrete proinflammatory mediators in response to LPS, but cytokine production by a prominent nonciliated bronchiolar epithelial cell,…”
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Laser Capture Microdissection and Real-Time Reverse Transcriptase/ Polymerase Chain Reaction of Bronchiolar Epithelium after Bleomycin by Betsuyaku, Tomoko, Griffin, Gail L, Watson, Mark A, Senior, Robert M

“…Terminal airways are affected in many lung diseases and toxic inhalations. To elucidate the changes in terminal airways in these diverse situations it will be…”
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Increased Basigin in Bleomycin-Induced Lung Injury by Betsuyaku, Tomoko, Kadomatsu, Kenji, Griffin, Gail L, Muramatsu, Takashi, Senior, Robert M

“…Basigin is expressed in many tissues during development, including lung. It is also found on tumor cells and in wounds where it is thought to stimulate…”
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Distal Airways in Mice Exposed to Cigarette Smoke: Nrf2-Regulated Genes Are Increased in Clara Cells by Adair-Kirk, Tracy L, Atkinson, Jeffrey J, Griffin, Gail L, Watson, Mark A, Kelley, Diane G, DeMello, Daphne, Senior, Robert M, Betsuyaku, Tomoko

“…Cigarette smoke (CS) is the main risk factor for chronic obstructive pulmonary disease (COPD). Terminal bronchioles are critical zones in the pathophysiology…”
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Tumor necrosis factor-alpha from macrophages enhances LPS-induced clara cell expression of keratinocyte-derived chemokine by Elizur, Arnon, Adair-Kirk, Tracy L, Kelley, Diane G, Griffin, Gail L, Demello, Daphne E, Senior, Robert M

“…Tumor necrosis factor (TNF)-alpha is a cytokine produced by alveolar macrophages in response to LPS in the lung. Clara cells are bronchiolar epithelial cells…”
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Elastin binds to a multifunctional 67-kilodalton peripheral membrane protein by Mecham, Robert P, Hinek, Aleksander, Entwistle, Ruth, Wrenn, David S, Griffin, Gail L, Senior, Robert M

“…Elastin binding proteins from plasma membranes of elastin-producing cells were isolated by affinity chromatography on immobilized elastin peptides. Three…”
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Smooth Muscle-Mediated Connective Tissue Remodeling in Pulmonary Hypertension by Mecham, Robert P., Whitehouse, Loren A., Wrenn, David S., Parks, William C., Griffin, Gail L., Senior, Robert M., Crouch, Edmond C., Stenmark, Kurt R., Voelkel, Norbert F.

“…Abnormal accumulation of connective tissue in blood vessels contributes to alterations in vascular physiology associated with disease states such as…”
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Nicotine is Chemotactic for Neutrophils and Enhances Neutrophil Responsiveness to Chemotactic Peptides by Totti, Noel, McCusker, Kevin T., Campbell, Edward J., Griffin, Gail L., Senior, Robert M.

“…Neutrophils contribute to chronic bronchitis and pulmonary emphysema associated with cigarette smoking. Nicotine was found to be chemotactic for human…”
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Expression Patterns of Laminin alpha 1 and alpha 5 in Human Lung during Development by Pierce, Richard A, Griffin, Gail L, Miner, Jeffrey H, Senior, Robert M

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Recombinant SP-D carbohydrate recognition domain is a chemoattractant for human neutrophils by Cai, G Z, Griffin, G L, Senior, R M, Longmore, W J, Moxley, M A

“…Human pulmonary surfactant protein D (SP-D) is a collagenous C-type lectin with high binding specificity to alpha-D-glucosyl residues. It is composed of four…”
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Entactin expression by rat lung and rat alveolar epithelial cells by Senior, R M, Griffin, G L, Mudd, M S, Moxley, M A, Longmore, W J, Pierce, R A

“…Although the composition of the subepithelial basement membrane of the alveolar septum has been studied in detail, there is relatively little information about…”
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PDGF AA homodimers are potent chemoattractants for fibroblasts and neutrophils, and for monocytes activated by lymphocytes or cytokines by Shure, D, Senior, R M, Griffin, G L, Deuel, T F

“…The A-chain homodimers of the platelet-derived growth factor (PDGF AA) are widely expressed in normal and transformed cells. The mitogenic properties of PDGF…”
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Expression of Laminin alpha 3, alpha 4, and alpha 5 Chains by Alveolar Epithelial Cells and Fibroblasts by Pierce, Richard A, Griffin, Gail L, Susan Mudd, M, Moxley, Michael A, Longmore, William J, Sanes, Joshua R, Miner, Jeffrey H, Senior, Robert M

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Characterization of biologically active domains on elastin: identification of a monoclonal antibody to a cell recognition site by Wrenn, David S, Griffin, Gail L, Senior, Robert M, Mecham, Robert P

“…Monoclonal antibodies to bovine alpha-elastin were characterized with solid-phase ELISA, Western blot, immunoprecipitation, and immunoaffinity chromatography…”
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Domain-specific Interactions between Entactin and Neutrophil Integrins by Gresham, Hattie D., Graham, Irene L., Griffin, Gail L., Hsieh, Jyh-Cheng, Dong, Li-Jin, Chung, Albert E., Senior, Robert M.

“…Extracellular matrix proteins activate neutrophils to up-regulate many physiologic functions that are necessary at sites of tissue injury. To elucidate the…”
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Keratinocyte-Targeted Expression of Human Laminin [gamma]2 Rescues Skin Blistering and Early Lethality of Laminin [gamma]2 Deficient Mice by Adair-Kirk, Tracy L, Griffin, Gail L, Meyer, Michelle J, Kelley, Diane G, Miner, Jeffrey H, Keene, Douglas R, Marinkovich, M. Peter, Ruppert, J. Michael, Uitto, Jouni, Senior, Robert M

“…Laminin-332 is a heterotrimeric basement membrane component comprised of the [alpha]3, ß3, and [gamma]2 laminin chains. Laminin-332 modulates epithelial cell…”
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Tumor Necrosis Factor-{alpha} from Macrophages Enhances LPS-Induced Clara Cell Expression of Keratinocyte-Derived Chemokine by Elizur, Arnon, Adair-Kirk, Tracy L, Kelley, Diane G, Griffin, Gail L, deMello, Daphne E, Senior, Robert M

“…Tumor necrosis factor (TNF)-alpha is a cytokine produced by alveolar macrophages in response to LPS in the lung. Clara cells are bronchiolar epithelial cells…”
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Human 92- and 72-kilodalton type IV collagenases are elastases by Senior, R M, Griffin, G L, Fliszar, C J, Shapiro, S D, Goldberg, G I, Welgus, H G

“…Elastin is critical to the structural integrity of a variety of connective tissues. Only a select group of enzymes has thus far been identified capable of…”
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Platelet-Derived Growth Factor and Transforming Growth Factor-β Enhance Tissue Repair Activities by Unique Mechanisms by Pierce, Glenn F., Mustoe, Thomas A., Lingelbach, Jane, Masakowski, Victoria R., Griffin, Gail L., Senior, Robert M., Deuel, Thomas F.

“…Platelet-derived growth factor (PDGF) and transforming growth factor-β (TGF-β) markedly potentiate tissue repair in vivo. In the present experiments, both in…”
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