Search Results - "Griffin, Frank"

Control of Mycobacterium avium subsp. paratuberculosis infection on a New Zealand pastoral dairy farm by Bates, Andrew, O'Brien, Rory, Liggett, Simon, Griffin, Frank

“…Johne's disease is a major production limiting disease of dairy cows caused by infection with Mycobacterium avium subsp. paratuberculosis in calf-hood. The…”
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Farmed deer: A veterinary model for chronic mycobacterial diseases that is accessible, appropriate and cost-effective by Griffin, Frank

“…Although most studies in immunology have used inbred mice as the experimental model to study fundamental immune mechanisms they have been proven to be limited…”
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The effect of sub-clinical infection with Mycobacterium avium subsp. paratuberculosis on milk production in a New Zealand dairy herd by Bates, Andrew, O'Brien, Rory, Liggett, Simon, Griffin, Frank

“…Johne's disease is a major production limiting disease of dairy cows. The disease is chronic, progressive, contagious and widespread; there is no treatment and…”
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The mammalian secreted RNases: mechanisms of action in host defence by Gupta, Sandeep K, Haigh, Brendan J, Griffin, Frank J, Wheeler, Thomas T

“…The mammalian ribonucleaseA family comprises a large group of structurally similar proteins which are secreted by a range of tissues and immune cells. Their…”
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Bovine milk RNases modulate pro-inflammatory responses induced by nucleic acids in cultured immune and epithelial cells by Gupta, Sandeep K., Haigh, Brendan J., Seyfert, Hans-Martin, Griffin, Frank J., Wheeler, Thomas T.

“…Activation of innate immune receptors by exogenous substances is crucial for the detection of microbial pathogens and a subsequent inflammatory response. The…”
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Global gene expression profiling of monocyte-derived macrophages from red deer (Cervus elaphus) genotypically resistant or susceptible to Mycobacterium avium subspecies paratuberculosis infection by Marfell, Brooke J., O’Brien, Rory, Griffin, J. Frank T.

“…► We investigate the response of cervine macrophages to MAP infection. ► Macrophages were obtained from Johne’s disease resistant (R) or susceptible (S) deer…”
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Innate immune markers that distinguish red deer (Cervus elaphus) selected for resistant or susceptible genotypes for Johne's disease by Dobson, Brooke, Liggett, Simon, O'Brien, Rory, Griffin, J Frank T

“…While many factors contribute to resistance and susceptibility to infectious disease, a major component is the genotype of the host and the way in which it is…”
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Identification of Immune Parameters To Differentiate Disease States among Sheep Infected with Mycobacterium avium subsp. paratuberculosis by Gillan, Sonia, O'Brien, Rory, Hughes, Alan D, Griffin, J Frank T

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Differential Immune Responses of Red Deer (Cervus elaphus) following Experimental Challenge with Mycobacterium avium subsp. paratuberculosis by Robinson, Mark, O'Brien, Rory, Mackintosh, Colin, Griffin, Frank

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Use of ethanol extract of Mycobacterium bovis for detection of specific antibodies in sera of farmed red deer (Cervus elaphus) with bovine tuberculosis by Wadhwa, Ashutosh, Johnson, Rachel E, Mackintosh, Colin G, Griffin, J Frank T, Waters, W Ray, Bannantine, John P, Eda, Shigetoshi

“…Bovine tuberculosis (bTB) in wildlife species poses a threat to domestic livestock in many situations. Control programs for bTB in livestock depend on testing…”
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Development of the thymus and Peyer's patches in the first year of life in red deer ( Cervus elaphus) by Dobson, Brooke J., Mackintosh, Colin G., Griffin, J. Frank T.

“…In young ruminants, as in most animals, the thymus and Peyer's patches (PP) play a key role in immune function. In sheep and cattle it has been shown that they…”
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A comparison of ovine monocyte‐derived macrophage function following infection with Mycobacterium avium ssp. avium and Mycobacterium avium ssp. paratuberculosis by Berger, Sven T, Griffin, Frank T

“…Mycobacterium avium ssp. paratuberculosis causes Johne's disease in ruminants, whereas the antigenically and genetically similar subspecies Mycobacterium avium…”
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Ovine immune parameters following immunisation against Mycobacterium avium ssp. paratuberculosis using a lipid-based live-cell vaccine by Gillan, Sonia, Hughes, Alan D., O’Brien, Rory, Griffin, J. Frank T.

“…Current commercial sheep vaccines against Mycobacterium avium subspecies paratuberculosis (MAP) are based on the use of live or killed cells from avirulent MAP…”
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Immunoglobulin G1 enzyme-linked immunosorbent assay for diagnosis of Johne's Disease in red deer (Cervus elaphus) by Griffin, J Frank T, Spittle, Evelyn, Rodgers, Christie R, Liggett, Simon, Cooper, Marc, Bakker, Douwe, Bannantine, John P

“…This study was designed to develop a customized enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of Johne's disease (JD) in farmed deer. Two…”
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Efficacy of novel lipid-formulated whole bacterial cell vaccines against Mycobacterium avium subsp. paratuberculosis in sheep by Griffin, J. Frank T, Hughes, Alan D, Liggett, Simon, Farquhar, Philip A, Mackintosh, Colin G, Bakker, Douwe

“…Abstract Mycobacterium avium subsp. paratuberculosis [ MAP ], the causative agent of enteric Johne's disease, incurs significant economic losses to the…”
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Peripheral blood mononuclear cell population changes associated with age and Mycobacterium avium subspecies paratuberculosis infection in red deer ( Cervus elaphus) by Robinson, Mark W., O’Brien, Rory, Mackintosh, Colin G., Griffin, J. Frank T.

“…In this study we aimed to document the maturation of the immune system in red deer and investigate the hypothesis that an immature immune system may predispose…”
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Autoreactive antibodies are present in sheep with Johne's disease and cross-react with Mycobacterium avium subsp. paratuberculosis antigens by Berger, Sven, Bannantine, John P., T. Griffin, J. Frank

“…Mycobacterial infection has been linked to the generation of autoantibodies, including anti-neutrophil cytoplasmic autoantibodies (ANCA), in clinical studies…”
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Isolation of High-Affinity Single-Chain Antibodies against Mycobacterium avium subsp. paratuberculosis Surface Proteins from Sheep with Johne's Disease by Berger, Sven, Hinz, Dominik, Bannantine, John P, Griffin, J. Frank T

“…Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, causes significant economic losses to the livestock farming industry…”
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Longitudinal Pathogenesis Study of Young Red Deer (Cervus elaphus ) after Experimental Challenge with Mycobacterium avium subsp. paratuberculosis (MAP) by Clark, Gary, Mackintosh, Colin, Tolentino, Brendan, Liggett, Simon, de Lisle, Geoff, Griffin, Frank

“…Paratuberculosis progresses more quickly in young red deer than in sheep or cattle. This study describes the clinical, immunological and pathological changes…”
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A Ramberg−Bäcklund Approach to the Synthesis of C-Glycosides, C-Linked Disaccharides, and C-Glycosyl Amino Acids by Paterson, Duncan E., Griffin, Frank K., Alcaraz, Marie-Lyne, Taylor, Richard J. K.

“…Synthetic applications of exo‐glycals, derived from S‐glycoside dioxides using the Meyers variant of the Ramberg−Bäcklund rearrangement, are described. These…”
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