Search Results - "Griffin, Edward"

Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer's and Parkinson's disease models of neurodegeneration by Griffin, Edward F, Yan, Xiaohui, Caldwell, Kim A, Caldwell, Guy A

“…Abstract Commonalities and, in some cases, pathological overlap between neurodegenerative diseases have led to speculation that targeting of underlying…”
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Damage Control Resuscitation by Cap, Andrew P, Pidcoke, Heather F, Spinella, Philip, Strandenes, Geir, Borgman, Matthew A, Schreiber, Martin, Holcomb, John, Tien, Homer Chin-Nan, Beckett, Andrew N, Doughty, Heidi, Woolley, Tom, Rappold, Joseph, Ward, Kevin, Reade, Michael, Prat, Nicolas, Ausset, Sylvain, Kheirabadi, Bijan, Benov, Avi, Griffin, Edward P, Corley, Jason B, Simon, Clayton D, Fahie, Roland, Jenkins, Donald, Eastridge, Brian J, Stockinger, Zsolt

“…Damage control resuscitation (DCR) is a strategy for resuscitating patients from hemorrhagic shock to rapidly restore homeostasis. Efforts are focused on blood…”
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Genetic and Pharmacological Discovery for Alzheimer’s Disease Using Caenorhabditis elegans by Griffin, Edward F, Caldwell, Kim A, Caldwell, Guy A

“…The societal burden presented by Alzheimer’s disease warrants both innovative and expedient means by which its underlying molecular causes can be both…”
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The effectiveness of an interactive audio‐tactile map for the process of cognitive mapping and recall among people with visual impairments by Griffin, Edward, Picinali, Lorenzo, Scase, Mark

“…Background People with visual impairments can experience numerous challenges navigating unfamiliar environments. Systems that operate as prenavigation tools…”
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Tobramycin-Treated Pseudomonas aeruginosa PA14 Enhances Streptococcus constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System by Price, Katherine E, Naimie, Amanda A, Griffin, Edward F, Bay, Charles, O'Toole, George A

“…Cystic fibrosis (CF) is a human genetic disorder which results in a lung environment that is highly conducive to chronic microbial infection. Over the past…”
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ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans by Griffin, Edward F, Scopel, Samuel E, Stephen, Cayman A, Holzhauer, Adam C, Vaji, Madeline A, Tuckey, Ryan A, Berkowitz, Laura A, Caldwell, Kim A, Caldwell, Guy A

“…Allele-specific distinctions in the human apolipoprotein E ( ) locus represent the best-characterized genetic predictor of Alzheimer's disease (AD) risk…”
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An economic evaluation of eptinezumab for the preventive treatment of migraine in the UK, with consideration for natural history and work productivity by Griffin, Edward, Shirley, Gawain, Lee, Xin Ying, Awad, Susanne F., Tyagi, Alok, Goadsby, Peter J.

“…Background Migraine is a highly prevalent neurological disease with a substantial societal burden due to lost productivity. From a societal perspective, we…”
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Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation by van der Welle, Reini E N, Jobling, Rebekah, Burns, Christian, Sanza, Paolo, van der Beek, Jan A, Fasano, Alfonso, Chen, Lan, Zwartkruis, Fried J, Zwakenberg, Susan, Griffin, Edward F, ten Brink, Corlinda, Veenendaal, Tineke, Liv, Nalan, van Ravenswaaij‐Arts, Conny M A, Lemmink, Henny H, Pfundt, Rolph, Blaser, Susan, Sepulveda, Carolina, Lozano, Andres M, Yoon, Grace, Santiago‐Sim, Teresa, Asensio, Cedric S, Caldwell, Guy A, Caldwell, Kim A, Chitayat, David, Klumperman, Judith

“…Vacuolar protein sorting 41 (VPS41) is as part of the Homotypic fusion and Protein Sorting (HOPS) complex required for lysosomal fusion events and, independent…”
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In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells by QIANRU YU, GRIFFIN, Edward F, MOREAU-MARQUIS, Sophie, SCHWARTZMAN, Joseph D, STANTON, Bruce A, O'TOOLE, George A

“…Aztreonam for inhalation solution (AZLI) was recently approved by the FDA for treating cystic fibrosis (CF) patients infected with Pseudomonas aeruginosa. Here…”
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Vacuolar protein sorting protein 41 (VPS41) at an intersection of endosomal traffic in neurodegenerative disease by Griffin, Edward, Caldwell, Kim, Caldwell, Guy

“…On the contrary, both the GTP- and GDP-locked states of arl-8 increased neurodegeneration. Because Arl8 was required for localization of Vps41 and Rab7 in…”
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A Singular Man: Cotton Mather Reappraised by GRIFFIN, EDWARD M.

“…Since very early in the nineteenth century, those pages, now stitched into six folio-sized volumes, passed via a still-uncertain provenance to the…”
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HIV enteropathy and 'Slim disease': Historical and current perspectives by Kapembwa, Moses Silungwe, Batman, Philip Anthony, Fleming, Simon Charles, Griffin, George Edward

“…Chronic diarrhoea and severe wasting associated with HIV infection were first described in East African patients as slim disease (SD) in 1985. The main…”
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Pseudomonas aeruginosa Exopolysaccharide Psl Promotes Resistance to the Biofilm Inhibitor Polysorbate 80 by ZEGANS, Michael E, WOZNIAK, Daniel, GRIFFIN, Edward, TOUTAIN-KIDD, Christine M, HAMMOND, John H, GARFOOT, Andrew, LAM, Joseph S

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cost-Effectiveness Analysis of Natriuretic Peptide Testing and Specialist Management in Patients with Suspected Acute Heart Failure by Griffin, Edward A., Wonderling, David, Ludman, Andrew J., Al-Mohammad, Abdallah, Cowie, Martin R., Hardman, Suzanna M.C., McMurray, John J.V., Kendall, Jason, Mitchell, Polly, Shote, Aminat, Dworzynski, Katharina, Mant, Jonathan

“…To determine the cost-effectiveness of natriuretic peptide (NP) testing and specialist outreach in patients with acute heart failure (AHF) residing off the…”
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Lung cancer screening by low-dose computed tomography: a cost-effectiveness analysis of alternative programmes in the UK using a newly developed natural history-based economic model by Griffin, Edward, Hyde, Chris, Long, Linda, Varley-Campbell, Jo, Coelho, Helen, Robinson, Sophie, Snowsill, Tristan

“…Abstract Background A systematic review of economic evaluations for lung cancer identified no economic models of the UK setting based on disease natural…”
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First person – Edward Griffin

“…ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career…”
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The role of balanced time perspective on student well-being and mental health: A mixed-methods study by Griffin, Edward, Wildbur, Diane

“…This two-phase mixed-methods study examined the effects of Time Perspective (TP) and Balanced Time Perspective (BTP) on the subjective well-being (SWB), and…”
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An Economic Analysis of Critical Care Nurse Resourcing Following the Uptake of Ready-to-Administer Noradrenaline for Hypotensive Shock in Adults in England by Griffin, Edward, Tweedie, Oliver, Kirk-Bayley, Justin

“…Introduction Ready-to-administer formulations for intravenous administration of noradrenaline are now broadly recommended and predicted to reduce pressure on…”
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Digital soil mapping of coarse fragments in southwest Australia: Targeting simple features yields detailed maps by Holmes, Karen W., Griffin, Edward A., van Gool, Dennis

“…•Soil coarse fragment data tend to be unreliable, and difficult to model and map.•Survey and agronomic observations increased the dataset × 10…”
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Student experiences of neurodiversity in higher education: insights from the BRAINHE project by Griffin, Edward, Pollak, David

“…The number of students with identified learning differences (LDs) of all kinds is increasing in higher education. This qualitative study explored the…”
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