Search Results - "Griffin, Brenda"
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IHG-1 Amplifies TGF-β1 Signaling and Is Increased in Renal Fibrosis
Published in Journal of the American Society of Nephrology (01-09-2008)“…Induced in high glucose-1 (IHG-1) is an evolutionarily conserved gene transcript upregulated by high extracellular glucose concentrations, but its function is…”
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Association of Shelter Veterinarians veterinary medical care guidelines for spay-neuter programs
Published in Journal of the American Veterinary Medical Association (01-07-2008)“…As efforts to reduce the overpopulation and euthanasia of unwanted and unowned dogs and cats have increased, greater attention has been focused on spay-neuter…”
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Interesting Biopsy of a Patient with AKI on a Background of Systemic Mastocytosis: TH-PO077
Published in Journal of the American Society of Nephrology (01-11-2023)Get full text
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Mutation of the GM2 activator protein in a feline model of GM2 gangliosidosis
Published in Acta neuropathologica (01-11-2005)“…The G(M2) activator protein is required for successful degradation of G(M2) ganglioside by the A isozyme of lysosomal beta-N-acetylhexosaminidase (EC…”
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A Friend in Need: Activated Protein C Stabilizes YB-1 during Renal Ischemia Reperfusion Injury
Published in Journal of the American Society of Nephrology (01-11-2015)Get full text
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Studies on the Removal of Abnormal Prion Protein by Processes Used in the Manufacture of Human Plasma Products
Published in Vox sanguinis (01-03-2000)“…Background and Objectives: To identify if any process steps used in plasma fractionation may have a capability of removing agents of human transmissible…”
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Homeless patients requiring haemodialysis: incidence, caseload characteristics, and implications for care
Published in HRB open research (2024)“…Background Homelessness is a recognized risk factor for the development of kidney failure. However, the risk of requiring renal replacement therapy (RRT) in…”
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Monogenic causes of chronic kidney disease in adults
Published in Kidney international (01-04-2019)“…Approximately 500 monogenic causes of chronic kidney disease (CKD) have been identified, mainly in pediatric populations. The frequency of monogenic causes…”
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ANCA associated glomerulonephritis in tuberculosis: a paradoxical reaction
Published in BMJ case reports (15-06-2021)“…We present a case of antineutrophil cytoplasmic antibodies (ANCA)-associated rapidly progressive glomerulonephritis in the context of treatment of pulmonary…”
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Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria
Published in Biochimica et biophysica acta. Molecular basis of disease (01-04-2017)“…The highly conserved mitochondrial protein induced in high glucose-1 (IHG-1) functions to maintain mitochondrial quality and is associated with the development…”
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Synthesis and Biological Activity of a Novel 11a-Homo (Cyclohexyl) Prostaglandin
Published in Journal of medicinal chemistry (07-09-2000)“…The racemic cyclohexane-for-cyclopentane ring substitution analogue of the potent prostaglandin FP agonist cloprostenol (7) was synthesized from…”
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The Association of Shelter Veterinarians' 2016 Veterinary Medical Care Guidelines for Spay-Neuter Programs
Published in Journal of the American Veterinary Medical Association (15-07-2016)“…As community efforts to reduce the overpopulation and euthanasia of unwanted and unowned cats and dogs have increased, many veterinarians have increasingly…”
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Accuracy of a point-of-care luteinizing hormone test for help in distinguishing between sexually intact and ovariectomized or castrated domestic cats
Published in Journal of feline medicine and surgery (01-10-2018)“…Objectives The aim of this study was to determine the accuracy of a commercial luteinizing hormone (LH) test as an aid in distinguishing between sexually…”
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Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization
Published in The Journal of pharmacology and experimental therapeutics (01-07-1998)“…An FP prostaglandin (PG) receptor on the A7r5 rat aorta smooth muscle cell line has been characterized by assays of phosphoinositide (PI) turnover and…”
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The association between ambient UVB dose and ANCA-associated vasculitis relapse and onset
Published in Arthritis research & therapy (18-06-2022)“…Abstract Background The aetiology of ANCA-associated vasculitis (AAV) and triggers of relapse are poorly understood. Vitamin D (vitD) is an important…”
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Acute kidney Injury due to Alectinib, an Anaplastic Lymphoma Kinase inhibitor
Published in Journal of Onco-Nephrology (01-02-2021)“…Introduction: The array of unintended effects of targeted oncological treatments is still being elucidated. Cognizance of these effects is important since they…”
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IHG-1 increases mitochondrial fusion and bioenergetic function
Published in Diabetes (New York, N.Y.) (01-12-2014)“…Induced in high glucose-1 (IHG-1) is a conserved mitochondrial protein associated with diabetic nephropathy (DN) that amplifies profibrotic transforming growth…”
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The Irish Kidney Gene Project--Prevalence of Family History in Patients with Kidney Disease in Ireland
Published in Nephron (2015) (01-01-2015)“…The prevalence of kidney disease (KD) due to inherited genetic conditions in Ireland is unknown. The aim of this study was to characterise an adult kidney…”
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IHG-1 Promotes Mitochondrial Biogenesis by Stabilizing PGC-1α
Published in Journal of the American Society of Nephrology (01-08-2011)“…Increased expression of Induced-by-High-Glucose 1 (IHG-1) associates with tubulointerstitial fibrosis in diabetic nephropathy. IHG-1 amplifies TGF-β1…”
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