Search Results - "Griffié, Juliette"

Machine learning for cluster analysis of localization microscopy data by Williamson, David J., Burn, Garth L., Simoncelli, Sabrina, Griffié, Juliette, Peters, Ruby, Davis, Daniel M., Owen, Dylan M.

“…Quantifying the extent to which points are clustered in single-molecule localization microscopy data is vital to understanding the spatial relationships…”
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Event-driven acquisition for content-enriched microscopy by Mahecic, Dora, Stepp, Willi L., Zhang, Chen, Griffié, Juliette, Weigert, Martin, Manley, Suliana

“…A common goal of fluorescence microscopy is to collect data on specific biological events. Yet, the event-specific content that can be collected from a sample…”
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An agent-based model of molecular aggregation at the cell membrane by Griffié, Juliette, Peters, Ruby, Owen, Dylan M

“…Molecular clustering at the plasma membrane has long been identified as a key process and is associated with regulating signalling pathways across cell types…”
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Strategies for increasing the throughput of super-resolution microscopies by Mahecic, Dora, Testa, Ilaria, Griffié, Juliette, Manley, Suliana

“…Fluorescence microscopy methods have been developed to circumvent the diffraction limit by exploiting nonlinearities in the interactions between light and…”
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Correction of multiple-blinking artifacts in photoactivated localization microscopy by Jensen, Louis G., Hoh, Tjun Yee, Williamson, David J., Griffié, Juliette, Sage, Daniel, Rubin-Delanchy, Patrick, Owen, Dylan M.

“…Photoactivated localization microscopy (PALM) produces an array of localization coordinates by means of photoactivatable fluorescent proteins. However,…”
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Fluorescent d‑Amino Acids for Super-resolution Microscopy of the Bacterial Cell Wall by Zhang, Chen, Reymond, Luc, Rutschmann, Ophélie, Meyer, Mischa A., Denereaz, Julien, Qiao, Jiangtao, Ryckebusch, Faustine, Griffié, Juliette, Stepp, Willi L., Manley, Suliana

“…Fluorescent d-amino acids (FDAAs) have previously been developed to enable in situ highlighting of locations of bacterial cell wall growth. Most bacterial…”
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Cluster analysis for localisation-based data sets: dos and don'ts when quantifying protein aggregates by Panconi, Luca, Owen, Dylan M, Griffié, Juliette

“…Many proteins display a non-random distribution on the cell surface. From dimers to nanoscale clusters to large, micron-scale aggregations, these distributions…”
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Quantitative fibre analysis of single-molecule localization microscopy data by Peters, Ruby, Griffié, Juliette, Burn, Garth L., Williamson, David J., Owen, Dylan M.

“…Single molecule localization microscopy (SMLM) methods produce data in the form of a spatial point pattern (SPP) of all localized emitters. Whilst numerous…”
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Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation by Simoncelli, Sabrina, Griffié, Juliette, Williamson, David J., Bibby, Jack, Bray, Cara, Zamoyska, Rose, Cope, Andrew P., Owen, Dylan M.

“…Elucidating the mechanisms that controlled T cell activation requires visualization of the spatial organization of multiple proteins on the submicron scale…”
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Topographic prominence as a method for cluster identification in single-molecule localisation data by Griffié, Juliette, Boelen, Lies, Burn, Garth, Cope, Andrew P., Owen, Dylan M.

“…Single‐molecule localisation based super‐resolution fluorescence imaging produces maps of the coordinates of fluorescent molecules in a region of interest…”
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Dynamic Bayesian Cluster Analysis of Live‐Cell Single Molecule Localization Microscopy Datasets by Griffié, Juliette, Burn, Garth L., Williamson, David J., Peters, Ruby, Rubin‐Delanchy, Patrick, Owen, Dylan M.

“…Until recently, single‐molecule localization microscopy (SMLM) was constrained to the study of fixed cells, limiting analysis to the structural…”
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Bayesian cluster identification in single-molecule localization microscopy data by Rubin-Delanchy, Patrick, Burn, Garth L, Griffié, Juliette, Williamson, David J, Heard, Nicholas A, Cope, Andrew P, Owen, Dylan M

“…This paper reports a Bayesian approach for the automatic identification of the optimal clustering proposal in the analysis of single-molecule…”
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A framework for evaluating the performance of SMLM cluster analysis algorithms by Nieves, Daniel J., Pike, Jeremy A., Levet, Florian, Williamson, David J., Baragilly, Mohammed, Oloketuyi, Sandra, de Marco, Ario, Griffié, Juliette, Sage, Daniel, Cohen, Edward A. K., Sibarita, Jean-Baptiste, Heilemann, Mike, Owen, Dylan M.

“…Single-molecule localization microscopy (SMLM) generates data in the form of coordinates of localized fluorophores. Cluster analysis is an attractive route for…”
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Machine learning in microscopy - insights, opportunities and challenges by Cunha, Inês, Latron, Emma, Bauer, Sebastian, Sage, Daniel, Griffié, Juliette

“…Machine learning (ML) is transforming the field of image processing and analysis, from automation of laborious tasks to open-ended exploration of visual…”
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3D Bayesian cluster analysis of super-resolution data reveals LAT recruitment to the T cell synapse by Griffié, Juliette, Shlomovich, Leigh, Williamson, David J., Shannon, Michael, Aaron, Jesse, Khuon, Satya, L. Burn, Garth, Boelen, Lies, Peters, Ruby, Cope, Andrew P., Cohen, Edward A. K., Rubin-Delanchy, Patrick, Owen, Dylan M.

“…Single-molecule localisation microscopy (SMLM) allows the localisation of fluorophores with a precision of 10–30 nm, revealing the cell’s nanoscale…”
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A Bayesian cluster analysis method for single-molecule localization microscopy data by Griffié, Juliette, Shannon, Michael, Bromley, Claire L, Boelen, Lies, Burn, Garth L, Williamson, David J, Heard, Nicholas A, Cope, Andrew P, Owen, Dylan M, Rubin-Delanchy, Patrick

“…Griffié et al . describe a protocol to perform cluster analysis of data generated from single-molecule localization microscopy. Cell function is regulated by…”
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Differential nanoscale organisation of LFA-1 modulates T-cell migration by Shannon, Michael J, Pineau, Judith, Griffié, Juliette, Aaron, Jesse, Peel, Tamlyn, Williamson, David J, Zamoyska, Rose, Cope, Andrew P, Cornish, Georgina H, Owen, Dylan M

“…Effector T-cells rely on integrins to drive adhesion and migration to facilitate their immune function. The heterodimeric transmembrane integrin LFA-1 (αLβ2…”
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Quantification of fibrous spatial point patterns from single-molecule localization microscopy (SMLM) data by Peters, Ruby, Benthem Muñiz, Marta, Griffié, Juliette, Williamson, David J, Ashdown, George W, Lorenz, Christian D, Owen, Dylan M

“…Unlike conventional microscopy which produces pixelated images, SMLM produces data in the form of a list of localization coordinates-a spatial point pattern…”
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Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity by Burn, Garth L, Cornish, Georgina H, Potrzebowska, Katarzyna, Samuelsson, Malin, Griffié, Juliette, Minoughan, Sophie, Yates, Mark, Ashdown, George, Pernodet, Nicolas, Morrison, Vicky L, Sanchez-Blanco, Cristina, Purvis, Harriet, Clarke, Fiona, Brownlie, Rebecca J, Vyse, Timothy J, Zamoyska, Rose, Owen, Dylan M, Svensson, Lena M, Cope, Andrew P

“…Integrins are heterodimeric transmembrane proteins that play a fundamental role in the migration of leukocytes to sites of infection or injury. We found that…”
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The Nanoscale Organization of Signaling Domains at the Plasma Membrane by Griffié, Juliette, Burn, Garth, Owen, Dylan M

“…In this chapter, we present an overview of the role of the nanoscale organization of signaling domains in regulating key cellular processes. In particular, we…”
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