Search Results - "Griess, Kerstin"

ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cells by Uhlemeyer, Celina, Müller, Nadine, Griess, Kerstin, Wessel, Corinna, Schlegel, Caroline, Kuboth, Jennifer, Belgardt, Bengt-Frederik

“…Pancreatic beta cell death is a hallmark of type 1 and 2 diabetes (T1D/T2D), but the underlying molecular mechanisms are incompletely understood. Key proteins…”
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Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus by Uhlemeyer, Celina, Müller, Nadine, Rieck, Michael, Kuboth, Jennifer, Schlegel, Caroline, Grieß, Kerstin, Dorweiler, Tim Florian, Heiduschka, Sonja, Eckel, Jürgen, Roden, Michael, Lammert, Eckhard, Stoffel, Markus, Belgardt, Bengt-Frederik

“…Beta cell dysfunction and death are critical steps in the development of both type 1 and type 2 diabetes (T1D and T2D), but the underlying mechanisms are…”
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Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism by Pelligra, Angela, Mrugala, Jessica, Griess, Kerstin, Kirschner, Philip, Nortmann, Oliver, Bartosinska, Barbara, Köster, Andrea, Krupenko, Natalia I., Gebel, Dominik, Westhoff, Philipp, Steckel, Bodo, Eberhard, Daniel, Herebian, Diran, Belgardt, Bengt-Frederik, Schrader, Jürgen, Weber, Andreas P.M., Krupenko, Sergey A., Lammert, Eckhard

“…Type 2 diabetes is characterized by insulin hypersecretion followed by reduced glucose-stimulated insulin secretion (GSIS). Here we show that acute stimulation…”
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Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism by Pelligra, Angela, Mrugala, Jessica, Griess, Kerstin, Kirschner, Philip, Nortmann, Oliver, Bartosinska, Barbara, Köster, Andrea, Krupenko, Natalia I., Gebel, Dominik, Westhoff, Philipp, Steckel, Bodo, Eberhard, Daniel, Herebian, Diran, Belgardt, Bengt-Frederik, Schrader, Jürgen, Weber, Andreas P.M., Krupenko, Sergey A., Lammert, Eckhard

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E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice by Altenhofen, Delsi, Khuong, Jenny Minh-An, Kuhn, Tanja, Lebek, Sandra, Görigk, Sarah, Kaiser, Katharina, Binsch, Christian, Griess, Kerstin, Knebel, Birgit, Belgardt, Bengt-Frederik, Cames, Sandra, Eickelschulte, Samaneh, Stermann, Torben, Rasche, Axel, Herwig, Ralf, Weiss, Jürgen, Vogel, Heike, Schürmann, Annette, Chadt, Alexandra, Al-Hasani, Hadi

“…Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic…”
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Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis by Griess, Kerstin, Rieck, Michael, Müller, Nadine, Karsai, Gergely, Hartwig, Sonja, Pelligra, Angela, Hardt, Robert, Schlegel, Caroline, Kuboth, Jennifer, Uhlemeyer, Celina, Trenkamp, Sandra, Jeruschke, Kay, Weiss, Jürgen, Peifer-Weiss, Leon, Xu, Weiwei, Cames, Sandra, Yi, Xiaoyan, Cnop, Miriam, Beller, Mathias, Stark, Holger, Kondadi, Arun Kumar, Reichert, Andreas S., Markgraf, Daniel, Wammers, Marianne, Häussinger, Dieter, Kuss, Oliver, Lehr, Stefan, Eizirik, Decio, Lickert, Heiko, Lammert, Eckhard, Roden, Michael, Winter, Dominic, Al-Hasani, Hadi, Höglinger, Doris, Hornemann, Thorsten, Brüning, Jens C., Belgardt, Bengt-Frederik

“…Impaired proinsulin-to-insulin processing in pancreatic β-cells is a key defective step in both type 1 diabetes and type 2 diabetes (T2D) (refs. 1 , 2 ), but…”
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