Search Results - "Grieshaber, Nicole A"
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Translational gene expression control in Chlamydia trachomatis
Published in PloS one (27-01-2022)“…The human pathogen Chlamydia trachomatis proceeds through a multi phenotypic developmental cycle with each cell form specialized for different roles in…”
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The sRNA Regulated Protein DdbA Is Involved in Development and Maintenance of the Chlamydia trachomatis EB Cell Form
Published in Frontiers in cellular and infection microbiology (23-07-2021)“…The chlamydial small non coding RNA, IhtA, regulates the expression of both HctA and DdbA, the uncharacterized product of the C. trachomatis L2 CTL0322 gene…”
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Computational Modeling of the Chlamydial Developmental Cycle Reveals a Potential Role for Asymmetric Division
Published in mSystems (27-04-2023)“…Chlamydia trachomatis is an obligate intracellular bacterium that progresses through an essential multicell form developmental cycle. Infection of the host is…”
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The chlamydial transcriptional regulator Euo is a key switch in cell form developmental progression but is not involved in the committed step to the formation of the infectious form
Published in mSphere (25-09-2024)“…Bacteria in the genus are a significant health burden worldwide. They infect a wide range of vertebrate animals, including humans and domesticated animals. In…”
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Single-Inclusion Kinetics of Chlamydia trachomatis Development
Published in mSystems (13-10-2020)“…The obligate intracellular bacterial pathogen Chlamydia trachomatis is reliant on a developmental cycle consisting of two cell forms, termed the elementary…”
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Identification of the base-pairing requirements for repression of hctA translation by the small RNA IhtA leads to the discovery of a new mRNA target in Chlamydia trachomatis
Published in PloS one (10-03-2015)“…The non-coding small RNA, IhtA expressed by the obligate intracellular human pathogen Chlamydia trachomatis modulates the translation of HctA, a key protein…”
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Translation inhibition of the developmental cycle protein HctA by the small RNA IhtA is conserved across Chlamydia
Published in PloS one (11-10-2012)“…The developmental cycle of the obligate intracellular pathogen Chlamydia trachomatis serovar L2 is controlled in part by the small non-coding RNA (sRNA), IhtA…”
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Regulation of the Chlamydia trachomatis Histone H1-Like Protein Hc2 Is IspE Dependent and IhtA Independent
Published in Journal of Bacteriology (01-07-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Chlamydial Histone-DNA Interactions Are Disrupted by a Metabolite in the Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2004)“…The chlamydial developmental cycle is characterized by an intracellular replicative form, termed the reticulate body, and an extracellular form called the…”
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Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis
Published in Journal of visualized experiments (10-06-2020)“…The intracellular bacterial pathogen Chlamydia trachomatis undergoes a developmental cycle consisting of two morphologically discrete developmental forms. The…”
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Chlamydia trachomatis uses host cell dynein to traffic to the microtubule-organizing center in a p50 dynamitin-independent process
Published in Journal of cell science (15-09-2003)“…Chlamydiae are pathogenic obligate intracellular bacteria with a biphasic developmental cycle that involves cell types adapted for extracellular survival…”
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The role of the chlamydial effector CPAF in the induction of genomic instability
Published in Pathogens and disease (01-10-2014)Get full text
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Chlamydia trachomatis Causes Centrosomal Defects Resulting in Chromosomal Segregation Abnormalities
Published in Traffic (Copenhagen, Denmark) (01-08-2006)“…Chlamydiae traffic along microtubules to the microtubule organizing center (MTOC) to establish an intracellular niche within the host cell. Trafficking to the…”
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Follicle-Stimulating Hormone Suppresses Cytosolic 3,5,3′-Triiodothyronine-Binding Protein Messenger Ribonucleic Acid Expression in Rat Granulosa Cells
Published in Endocrinology (Philadelphia) (01-06-2003)“…FSH plays crucial roles in differentiation of granulosa cells and development of follicles. Considering the broad scope of FSH effects, a large number of genes…”
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15
A small RNA inhibits translation of the histone‐like protein Hc1 in Chlamydia trachomatis
Published in Molecular microbiology (01-01-2006)“…Summary The chromatin of chlamydial elementary bodies (EBs) is stabilized by proteins with sequence homology to eukaryotic H1. These histone homologues, termed…”
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Novel Embryonic Genes Are Preferentially Expressed by Autonomously Replicating Rat Embryonic and Neointimal Smooth Muscle Cells
Published in Circulation research (29-09-2000)“…We sought to identify and characterize the expression pattern of genes expressed by smooth muscle cells (SMCs) during periods of self-driven replication during…”
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Follicle-Stimulating Hormone-Responsive Cytoskeletal Genes in Rat Granulosa Cells: Class I β-Tubulin, Tropomyosin-4, and Kinesin Heavy Chain
Published in Endocrinology (Philadelphia) (01-01-2003)“…FSH regulates gene expression for granulosa cell differentiation and follicular development. Therefore, FSH-responsive genes are crucial, but only a few genes…”
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Differentiation of Granulosa Cell Line: Follicle-Stimulating Hormone Induces Formation of Lamellipodia and Filopodia via the Adenylyl Cyclase/Cyclic Adenosine Monophosphate Signal
Published in Endocrinology (Philadelphia) (01-09-2000)“…Abstract FSH plays a crucial role in granulosa cell differentiation and follicular development during the ovulation cycle. The early events of granulosa cell…”
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Expression of Porphyromonas gingivalis small RNA in response to hemin availability identified using microarray and RNA-seq analysis
Published in FEMS microbiology letters (01-02-2014)“…Abstract There is a significant body of work suggesting that sRNA-mediated post-transcriptional regulation is a conserved mechanism among pathogenic bacteria…”
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Tropoelastin Gene Expression in Individual Vascular Smooth Muscle Cells: Relationship to DNA Synthesis During Vascular Development and After Arterial Injury
Published in Circulation research (01-03-1996)“…After vascular injury, quiescent adult smooth muscle cells (SMCs) revert to a more immature synthetic-state phenotype concomitant with the onset of cell…”
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