Search Results - "Grierson, DS"

Accounting for the JKR-DMT transition in adhesion and friction measurements with atomic force microscopy by Grierson, D. S., Flater, E. E., Carpick, R. W.

“…Over the last 15 years, researchers have applied theories of continuum contact mechanics to nanotribology measurements to determine fundamental parameters and…”
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Foliar micro-morphology of Gasteria bicolour haw. (Asphodelaceae) from South Africa by Otang, WM, Grierson, DS, Ndip, R

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Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives:  A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains by Himmel, Daniel M, Das, Kalyan, Clark, Arthur D, Hughes, Stephen H, Benjahad, Abdellah, Oumouch, Said, Guillemont, Jérôme, Coupa, Sophie, Poncelet, Alain, Csoka, Imre, Meyer, Christophe, Andries, Koen, Nguyen, Chi Hung, Grierson, David S, Arnold, Eddy

“…In the treatment of AIDS, the efficacy of all drugs, including non-nucleoside inhibitors (NNRTIs) of HIV-1 reverse transcriptase (RT), has been limited by the…”
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Photodynamic Efficiency of Diethylene Glycol-Linked Glycoconjugated Porphyrins in Human Retinoblastoma Cells by Laville, Isabelle, Pigaglio, Sophie, Blais, Jean-Claude, Doz, François, Loock, Bernard, Maillard, Philippe, Grierson, David S., Blais, Jocelyne

“…Photodynamic therapy (PDT) is emerging as a new strategy for the conservative treatment of hereditary retinoblastoma. The glycoconjugated porphyrins…”
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Toward the Ultimate Tribological Interface: Surface Chemistry and Nanotribology of Ultrananocrystalline Diamond by Sumant, A. V., Grierson, D. S., Gerbi, J. E., Birrell, J., Lanke, U. D., Auciello, O., Carlisle, J. A., Carpick, R. W.

“…Ultrananocrystalline diamond (UNCD) may offer a solution to tribological failure of silicon‐based micromachines because of its outstanding mechanical…”
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A review of the phytochemistry, botany, pharmacology and toxicology of Arctotis arctotoides<?i> (L.F.) O. Hoffm. (Asteraceae) by Grierson, DS, Otang, WM, Afolayan, AJ

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PHYTOCHEMICAL AND ANTIOXIDANT INVESTIGATIONS OF A CLAUSENA ANISATA HOOK, A SOUTH AFRICAN MEDICINAL PLANT by Lawal, I. O, Grierson, D. S, Afolayan, A. J

“…Background: Clausena anisata (Willd). Hook (Rutaceae), also known as Iperepesi in Xhosa language is a medicinal plant widely used by herbalists for the…”
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Synthesis, cellular internalization and photodynamic activity of glucoconjugated derivatives of tri and tetra( meta-hydroxyphenyl)chlorins by Laville, I, Figueiredo, T, Loock, B, Pigaglio, S, Maillard, Ph, Grierson, D.S, Carrez, D, Croisy, A, Blais, J

“…Glucoconjugated tri and tetra( meta-hydroxyphenyl)chlorins have been synthesized in order to explore how glucoconjugation of the macrocycle affects the…”
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An ethnobotanical study of plants used for the treatment of diabetes in the Eastern Cape Province, South Africa by Erasto, P, Adebola, PO, Grierson, D S, Afolayan, A J

“…Diabetes mellitus is one of the commonest diseases affecting the citizens of both developed and poor countries. In South Africa, the number of people suffering…”
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THE ANTIBACTERIAL ACTIVITY OF CLAUSENA ANISATA HOOK, A SOUTH AFRICAN MEDICINAL PLANT by Lawal, I.O, Grierson, D.S, Afolayan, A.J

“…Background: Clausena anisata Hook also known as Iperepesi in Xhosa language is a medicinal plant used traditionally for the treatment of various ailments and…”
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Tosylation/mesylation of 4-hydroxy-3-nitro-2-pyridinones as an activation step in the construction of dihydropyrido[3,4- b] benzo[ f][1,4]thiazepin-1-one based anti-HIV agents by Storck, Pierre, Aubertin, Anne-Marie, Grierson, David S.

“…[Display omitted] Reaction of 4-hydroxy-3-nitropyridinone 8 with TsCl and MsCl, respectively, resulted in rapid and quantitative formation of ditosylate 13 and…”
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CYTOTOXICITY OF THREE SOUTH AFRICAN MEDICINAL PLANTS USING THE CHANG LIVER CELL LINE by Otang, Wilfred Mbeng, Grierson, Donald Scott, Ndip Ndip, Roland

“…Background: Arctotis arctotoides , Gasteria bicolor and Pittosporum viridiflorum are commonly used in the Eastern Cape, South Africa by traditional healers for…”
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Traceless solid-phase synthesis of 2,6,9-trisubstituted purines from resin bound 6-thiopurines by Brun, Virginie, Legraverend, Michel, Grierson, David S

“…The preparation of 6-chloro-2-iodo-9-tetrahydropyranylpurine ( 2 ), was achieved in three high yield steps from 6-chloropurine. This derivative was then…”
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The leaves of Pelargonium sidoides may substitute for its roots in the treatment of bacterial infections by Lewu, F.B., Grierson, D.S., Afolayan, A.J.

“…Pelargonium sidoides (Geraniaceae) is a medicinal plant used for the treatment of various infections including tuberculosis and bronchitis. Traditionally, only…”
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Studies on the toxicological effect of the aqueous extract of the fresh, dried and boiled berries of Solanum aculeastrum Dunal in male Wistar rats by Aboyade, Om, Yakubu, Mt, Grierson, Ds, Afolayan, Aj

“…The toxicological effect of the aqueous extract of fresh, dried and boiled berries of Solanum aculeastrum Dunal at 1, 10 and 25 mg/kg body weight was…”
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Antibacterial activity of some indigenous plants used for the treatment of wounds in the Eastern Cape, South Africa by Grierson, D.S., Afolayan, A.J.

“…The use of medicinal plants in the world, and especially in South Africa, contributes significantly to primary health care. This paper presents the findings of…”
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In vitro antioxidant activity of extracts from the leaves of Felicia muricata thunb. An underutilized medicinal plant in the Eastern Cape Province, South Africa by Ashafa, A O T, Grierson, D S, Afolayan, A J

“…Felicia muricata is a medicinal plant used for the management of different human and livestock diseases in the Eastern Cape Province of South Africa. The…”
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BENA435, a new cell-permeant photoactivated green fluorescent DNA probe by Erve, Alexandra, Saoudi, Yasmina, Thirot, Sylvie, Guetta-Landras, Corinne, Florent, Jean-Claude, Nguyen, Chi-Hung, Grierson, David S., Popov, Andrei V.

“…N′-(2,8-Dimethoxy-12-methyl-dibenzo [c,h] [1,5] naphthyridin-6-yl)-N,N-dimethyl-propane-1,3-diamine (BENA435) is a new cell-membrane permeant DNA dye with…”
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Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex by Legraverend, Michel, Tunnah, Paul, Noble, Martin, Ducrot, Pierre, Ludwig, Odile, Grierson, David S, Leost, Maryse, Meijer, Laurent, Endicott, Jane

“…A new series of 2,6,9-trisubstituted purines, characterized by the presence of a common alkynyl substituent at C-2 and a range of different anilino/benzylamino…”
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A study of the stability of tri(glucosyloxyphenyl)chlorin, a sensitizer for photodynamic therapy, in human colon tumoural cells: a liquid chromatography and MALDI-TOF mass spectrometry analysis by Laville, I, Pigaglio, S, Blais, J.-C, Loock, B, Maillard, Ph, Grierson, D.S, Blais, J

“…Graphic Asymmetrical glycoconjugated tetrapyrrolic macrocycles are under study as efficient sensitizers for photodynamic therapy (PDT). In this context, tri(…”
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