Search Results - "Grider, J. R."

Serotonin and colonic motility by Kendig, D. M., Grider, J. R.

“…The role of serotonin (5‐hydroxytryptamine [5‐HT]) in gastrointestinal motility has been studied for over 50 years. Most of the 5‐HT in the body resides in the…”
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Stimulation of synthesis and release of brain‐derived neurotropic factor from intestinal smooth muscle cells by substance P and pituitary adenylate cyclase‐activating peptide by Al‐Qudah, M., Alkahtani, R., Akbarali, H. I., Murthy, K. S., Grider, J. R.

“…Background Brain‐derived neurotrophic factor (BDNF) is a neurotrophin present in the intestine where it participates in survival and growth of enteric neurons,…”
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Enteric motor and interneuronal circuits controlling motility by Bornstein, J. C., Costa, M., Grider, J. R.

“…The enteric nervous system regulates intestinal motility. It contains intrinsic sensory neurones, several types of interneurones and excitatory and inhibitory…”
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Reciprocal activity of longitudinal and circular muscle during intestinal peristaltic reflex by Grider, J R

“…A two-compartment, flat-sheet preparation of rat colon was devised, which enabled exclusive measurement of longitudinal muscle activity during the ascending…”
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5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine by GRIDER, J. R, FOXX-ORENSTEIN, A. E, JIN, J.-G

“…The peristaltic reflex induced by mucosal stimuli is mediated by intrinsic sensory calcitonin gene-related peptide (CGRP) neurons activated by…”
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Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors by Jin, J G, Foxx-Orenstein, A E, Grider, J R

“…Previous studies have shown that the intestinal peristaltic reflex initiated by mucosal stimulation is mediated by release of 5-hydroxytryptamine (HT) from…”
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Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis by Grider, J R

“…Involvement of vasoactive intestinal peptide (VIP) and nitric oxide (NO) in neurally induced relaxation was examined in smooth muscle from rat colon…”
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Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestine by Foxx-Orenstein, AE, Kuemmerle, JF, Grider, JR

“…BACKGROUND & AIMS: The role of 5-hydroxytryptamine (5-HT) in regulating the peristaltic reflex in humans is unknown. The neural pathways subserving peristalsis…”
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5-HT released by mucosal stimuli initiates peristalsis by activating 5-HT4/5-HT1p receptors on sensory CGRP neurons by Grider, J R, Kuemmerle, J F, Jin, J G

“…The intestinal peristaltic reflex can be elicited by mucosal stimulation or circular muscle stretch. Muscle stretch activates extrinsic, whereas mucosal…”
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The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF by Grider, J R, Piland, B E

“…Short-chain fatty acids (SCFAs) accelerate colonic transit. This study examined whether this action was mediated by activation of the peristaltic reflex. SCFAs…”
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CGRP as a transmitter in the sensory pathway mediating peristaltic reflex by Grider, J R

“…The presence of calcitonin gene-related peptide (CGRP) in enteric and dorsal root ganglion neurons suggests that it might be involved as a transmitter in the…”
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Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells by Teng, B, Murthy, K S, Kuemmerle, J F, Grider, J R, Sase, K, Michel, T, Makhlouf, G M

“…The aim of this study was to identify the nitric oxide synthase (NOS) isoform expressed in freshly dispersed rabbit gastric smooth muscle cells and in cultured…”
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Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C by Al-Qudah, M, Anderson, C D, Mahavadi, S, Bradley, Z L, Akbarali, H I, Murthy, K S, Grider, J R

“…Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of proteins best known for its role in neuronal survival, differentiation,…”
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Role of cholecystokinin in the regulation of gastrointestinal motility by Grider, J R

“…Cholecystokinin, a hormone released from endocrine cells of the upper small intestine in response to amino acids and fatty acids in chyme, has potent effects…”
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Regulation of excitatory neural input to longitudinal intestinal muscle by myenteric interneurons by Grider, J R

“…The circuit of myenteric interneurons that regulate excitatory input to longitudinal colonic muscle was identified using dispersed ganglia and longitudinal…”
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Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release by Grider, J R, Murthy, K S, Jin, J G, Makhlouf, G M

“…The source of nitric oxide (NO) and its role in neurally induced relaxation was examined in smooth muscle of the stomach and tenia coli. Field stimulation of…”
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Distinct populations of sensory neurons mediate the peristaltic reflex elicited by muscle stretch and mucosal stimulation by Grider, JR, Jin, JG

“…Recent studies suggest that muscle stretch and mucosal stimulation elicit intestinal peristalsis by activating distinct populations of sensory neurons that…”
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Regulation of colonic propulsion by enteric excitatory and inhibitory neurotransmitters by Foxx-Orenstein, A E, Grider, J R

“…The contribution of excitatory and inhibitory motor neurotransmitters to colonic propulsion was examined in isolated segments of guinea pig colon. Synthetic…”
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Interplay of somatostatin, opioid, and GABA neurons in the regulation of the peristaltic reflex by Grider, J R

“…The interplay of somatostatin, gamma-aminobutyric acid (GABA), and opioid neurons in the regulation of the descending relaxation phase of peristalsis was…”
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Sequential activation of heterotrimeric and monomeric G proteins mediates PLD activity in smooth muscle by Murthy, K S, Zhou, H, Grider, J R, Makhlouf, G M

“…The identity of G proteins mediating CCK-stimulated phospholipase D (PLD) activity was determined in intestinal smooth muscle cells. CCK-8 activated G(q/11),…”
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