Search Results - "Grewe, Bastian"

Nuclear RNA Export and Packaging Functions of HIV-1 Rev Revisited by Blissenbach, Maik, Grewe, Bastian, Hoffmann, Bianca, Brandt, Sabine, Uberla, Klaus

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CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs by Xiao, Han, Wyler, Emanuel, Milek, Miha, Grewe, Bastian, Kirchner, Philipp, Ekici, Arif, Silva, Ana Beatriz Oliveira Villela, Jungnickl, Doris, Full, Florian, Thomas, Marco, Landthaler, Markus, Ensser, Armin, Überla, Klaus

“…The HIV-1 Rev protein is a nuclear export factor for unspliced and incompletely spliced HIV-1 RNAs. Without Rev, these intron-retaining RNAs are trapped in the…”
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The HIV 5′ Gag Region Displays a Specific Nucleotide Bias Regulating Viral Splicing and Infectivity by Grewe, Bastian, Vogt, Carolin, Horstkötter, Theresa, Tippler, Bettina, Xiao, Han, Müller, Bianca, Überla, Klaus, Wagner, Ralf, Asbach, Benedikt, Bohne, Jens

“…Alternative splicing and the expression of intron-containing mRNAs is one hallmark of HIV gene expression. To facilitate the otherwise hampered nuclear export…”
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The HIV-1 Rev protein enhances encapsidation of unspliced and spliced, RRE-containing lentiviral vector RNA by Grewe, Bastian, Ehrhardt, Katrin, Hoffmann, Bianca, Blissenbach, Maik, Brandt, Sabine, Uberla, Klaus

“…During the RNA encapsidation process of human immunodeficiency virus (HIV) viral genomic, unspliced RNA (gRNA) is preferentially incorporated into assembling…”
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Cytoplasmic Utilization of Human Immunodeficiency Virus Type 1 Genomic RNA Is Not Dependent on a Nuclear Interaction with Gag by GREWE, Bastian, HOFFMANN, Bianca, OHS, Inga, BLISSENBACH, Maik, BRANDT, Sabine, TIPPLER, Bettina, GRUNWALD, Thomas, ÜBERLA, Klaus

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Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation by Brandt, Sabine, Blissenbach, Maik, Grewe, Bastian, Konietzny, Rebecca, Grunwald, Thomas, Uberla, Klaus

“…The main function attributed to the Rev proteins of immunodeficiency viruses is the shuttling of viral RNAs containing the Rev responsive element (RRE) via the…”
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Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus by Kamdem Toukam, Donatien, Tenbusch, Matthias, Stang, Alexander, Temchura, Vladimir, Storcksdieck Genannt Bonsmann, Michael, Grewe, Bastian, Koch, Stefanie, Meyerhans, Andreas, Nchinda, Godwin, Kaptue, Lazare, Uberla, Klaus

“…Although human immunodeficiency type 1 (HIV-1) infection induces strong antibody responses to the viral envelope glycoprotein (Env) only a few of these…”
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Detection and Cloning of Spliced Transcripts by RT-PCR by Bianca Hoffmann, Bastian Grewe

“…Using a Reverse Transcriptase-PCR approach spliced transcripts can be converted to cDNA, amplified and cloned into an expression plasmid. Sequencing of the…”
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Packaging of Retroviral RNA into Viral Particles Analyzed by Quantitative Reverse Transcriptase-PCR by Bianca Hoffmann, Bastian Grewe

“…Formation of viral particles and packaging of genomic retroviral RNA into these particles are important steps in the late phase of the viral replication cycle…”
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Generation of T follicular helper cells in vitro: requirement for B‐cell receptor cross‐linking and cognate B‐ and T‐cell interaction by Kolenbrander, Anne, Grewe, Bastian, Nemazee, David, Überla, Klaus, Temchura, Vladimir

“…Summary The minimum requirements for in vitro modelling of natural CD4+ T‐cell differentiation into T follicular helper (Tfh) cells are still under…”
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Generation of T follicular helper cells inￂ vitro: requirement for B-cell receptor cross-linking and cognate B- and T-cell interaction by Kolenbrander, Anne, Grewe, Bastian, Nemazee, David, Uberla, Klaus, Temchura, Vladimir

“…Summary The minimum requirements for in vitro modelling of natural CD4+ T-cell differentiation into T follicular helper (Tfh) cells are still under…”
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Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity by Ambrosius, Björn, Faissner, Simon, Guse, Kirsten, von Lehe, Marec, Grunwald, Thomas, Gold, Ralf, Grewe, Bastian, Chan, Andrew

“…HIV-associated neurocognitive disorders (HAND) affect about 50% of infected patients despite combined antiretroviral therapy (cART). Ongoing compartmentalized…”
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The human immunodeficiency virus type 1 Rev protein: ménage à trois during the early phase of the lentiviral replication cycle by Grewe, Bastian, Überla, Klaus

“…The Rev protein of human immunodeficiency viruses (HIV) has long been recognized to be essential for the late phase of the virus replication cycle, due to its…”
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Cytoplasmic HIV-RNA in monocytes determines microglial activation and neuronal cell death in HIV-associated neurodegeneration by Faissner, Simon, Ambrosius, Björn, Schanzmann, Kirsten, Grewe, Bastian, Potthoff, Anja, Münch, Jan, Sure, Ulrich, Gramberg, Thomas, Wittmann, Sabine, Brockmeyer, Norbert, Überla, Klaus, Gold, Ralf, Grunwald, Thomas, Chan, Andrew

“…Despite highly active antiretroviral therapy, HIV-associated neurocognitive disorders (HAND) are still highly prevalent. Direct neurotoxicity of microglia…”
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HIV-derived lentiviral particles promote T-cell independent activation and differentiation of naive cognate conventional B2-cellsin vitro by Gardt, Oliver, Grewe, Bastian, Tippler, Bettina G, Überla, Klaus, Temchura, Vladimir V

“…In animal models, lentiviral particles (LP) were shown to be promising HIV vaccine candidates. Since little is known about the direct impact of LP on…”
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HIV-derived lentiviral particles promote T-cell independent activation and differentiation of naïve cognate conventional B2-cells in vitro by Gardt, Oliver, Grewe, Bastian, Tippler, Bettina G, Überla, Klaus, Temchura, Vladimir V

“…Highlights • The direct impact of lentiviral particles on cognate B cells in vitro was shown. • Activation events in B-cells after the contact with lentiviral…”
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