Search Results - "Grewal, Yadveer S."
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Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker
Published in Nature communications (04-12-2018)“…Epigenetic reprogramming in cancer genomes creates a distinct methylation landscape encompassing clustered methylation at regulatory regions separated by large…”
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Proteomic comparison of mcf-7 tumoursphere and monolayer cultures
Published in PloS one (20-12-2012)“…Breast cancer is a heterogeneous disease, composed of tumour cells with differing gene expressions and phenotypes. Very few antigens have been identified and a…”
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Multiplexed SERS Detection of Soluble Cancer Protein Biomarkers with Gold–Silver Alloy Nanoboxes and Nanoyeast Single-Chain Variable Fragments
Published in Analytical chemistry (Washington) (04-09-2018)“…Highly sensitive, multiplexed detection of soluble cancer protein biomarkers can facilitate early cancer screening as well as enable real-time monitoring of…”
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A SERS microfluidic platform for targeting multiple soluble immune checkpoints
Published in Biosensors & bioelectronics (01-02-2019)“…Immune checkpoint blockade therapies are promising next generation immunotherapeutic treatments for cancer. Whilst sequential solid biopsies are an invaluable…”
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Duplex Microfluidic SERS Detection of Pathogen Antigens with Nanoyeast Single-Chain Variable Fragments
Published in Analytical chemistry (Washington) (07-10-2014)“…Quantitative and accurate detection of multiple biomarkers would allow for the rapid diagnosis and treatment of diseases induced by pathogens. Monoclonal…”
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Nano-yeast–scFv probes on screen-printed gold electrodes for detection of Entamoeba histolytica antigens in a biological matrix
Published in Biosensors & bioelectronics (15-05-2014)“…The time and costs associated with monoclonal antibody production limit the potential for portable diagnostic devices to penetrate the market. Replacing the…”
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Label-free electrochemical detection of an Entamoeba histolytica antigen using cell-free yeast-scFv probes
Published in Chemical communications (Cambridge, England) (21-02-2013)“…Inexpensive, simple and quick detection of pathogen antigens in human samples is a key global health objective. Limiting factors include the cost and…”
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Nanoyeast and Other Cell Envelope Compositions for Protein Studies and Biosensor Applications
Published in ACS applied materials & interfaces (16-11-2016)“…Rapid progress in disease biomarker discovery has increased the need for robust detection technologies. In the past several years, the designs of many…”
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Enhancing Protein Capture Using a Combination of Nanoyeast Single-Chain Fragment Affinity Reagents and Alternating Current Electrohydrodynamic Forces
Published in Analytical chemistry (Washington) (01-12-2015)“…New high-performance detection technologies and more robust protein capture agents can be combined to both rapidly and specifically capture and detect protein…”
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Biosensing made easy with PEG-targeted bi-specific antibodies
Published in Chemical communications (Cambridge, England) (28-04-2016)“…Whilst recent advances in nanotechnology have yielded many new biosensing capabilities, innovative biological attachment and detection modalities remain…”
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Structural Characterization of Nanoyeast Single-Chain Fragment Variable Affinity Reagents
Published in Journal of physical chemistry. C (04-06-2015)“…Nanoyeast single-chain variable fragments (nanoyeast-scFv) are a new class of low-cost and stable protein capture agents developed as alternatives to full…”
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