Search Results - "Grewal, Ravinder"
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Selumetinib-Enhanced Radioiodine Uptake in Advanced Thyroid Cancer
Published in The New England journal of medicine (14-02-2013)“…Inhibition of mitogen-activated protein kinase resulted in an increase in expression of the sodium–iodide symporter in 12 of 20 patients, 8 of whom had…”
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Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid Cancers
Published in The journal of clinical endocrinology and metabolism (01-05-2019)“…Abstract Context BRAFV600E mutant thyroid cancers are often refractory to radioiodine (RAI). Objectives To investigate the utility and molecular underpinnings…”
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Genomic and Transcriptomic Characteristics of Metastatic Thyroid Cancers with Exceptional Responses to Radioactive Iodine Therapy
Published in Clinical cancer research (14-04-2023)“…The determinants of response or resistance to radioiodine (RAI) are unknown. We aimed to identify genomic and transcriptomic factors associated with structural…”
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PET-adapted sequential salvage therapy with brentuximab vedotin followed by augmented ifosamide, carboplatin, and etoposide for patients with relapsed and refractory Hodgkin's lymphoma: a non-randomised, open-label, single-centre, phase 2 study
Published in The lancet oncology (01-03-2015)“…Summary Background Pre-transplantation18 F-fluorodeoxyglucose (FDG) PET-negativity is one of the strongest predictors of outcome after high-dose therapy and…”
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Enhancing Radioiodine Incorporation in BRAF -Mutant, Radioiodine-Refractory Thyroid Cancers with Vemurafenib and the Anti-ErbB3 Monoclonal Antibody CDX-3379: Results of a Pilot Clinical Trial
Published in Thyroid (New York, N.Y.) (01-03-2022)“…Oncogenic activation of mitogen-activated protein kinase (MAPK) signaling is associated with radioiodine refractory (RAIR) thyroid cancer. Preclinical models…”
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Novel Approaches to Thyroid Cancer Treatment and Response Assessment
Published in Seminars in nuclear medicine (01-03-2016)“…The incidence of thyroid cancer has been increasing. After total thyroidectomy of well-differentiated thyroid tumors with intermediate- or high-risk features…”
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Real-Time Prognosis for Metastatic Thyroid Carcinoma Based on 2-[18F]Fluoro-2-Deoxy-d-Glucose-Positron Emission Tomography Scanning
Published in The journal of clinical endocrinology and metabolism (01-02-2006)“…Context/Objective: Approximately 15% of thyroid cancer patients develop subsequent metastases. The clinical course of patients with metastatic thyroid…”
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Assessment of salivary gland function after 177Lu-PSMA radioligand therapy: Current concepts in imaging and management
Published in Translational oncology (01-07-2022)“…•The United States food and drug administration has recently granted approval to the targeted 177Lu-PSMA-617 therapy in prostate cancer patients.•Salivary…”
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A low postoperative nonstimulated serum thyroglobulin level does not exclude the presence of radioactive iodine avid metastatic foci in intermediate-risk differentiated thyroid cancer patients
Published in Thyroid (New York, N.Y.) (01-04-2013)“…Postsurgical thyrotropin (TSH)-stimulated serum thyroglobulin (Tg) level can be used to predict the likelihood of finding radioactive iodine (RAI) avid…”
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Next-generation ALK inhibitors are highly active in ALK-positive large B-cell lymphoma
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Incidental Detection of Medullary Thyroid Carcinoma by 68Ga-DOTATATE PET/CT in a Patient With Neuroendocrine Tumor Liver Metastases
Published in Clinical nuclear medicine (01-02-2018)“…ABSTRACTGa-DOTATATE, a positron-emitting somatostatin analog, has been approved by the Food and Drug Administration for imaging neuroendocrine tumors (NETs)…”
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Treatment Response and Clinical Outcomes of Well-Differentiated High-Grade Neuroendocrine Tumors to Lutetium-177-DOTATATE
Published in Neuroendocrinology (01-11-2022)“…Lutetium-177 (177Lu)-DOTATATE received FDA approval in 2018 to treat somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (NETs). Little…”
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Toward individualized dosimetry for radiopharmaceutical therapy in day-to-day clinical practice of nuclear oncology: overcoming heterogeneity of radiation-absorbed dose to tumor and critical organs
Published in European journal of nuclear medicine and molecular imaging (01-01-2024)Get full text
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The use of single-timepoint images to link administered radioiodine activity (MBq) to a prescribed lesion radiation-absorbed dose (cGy): a regression-based prediction interval tool for the management of well-differentiated thyroid cancer patients
Published in European journal of nuclear medicine and molecular imaging (01-08-2023)“…Purpose To introduce a biomarker-based dosimetry method for the rational selection of a treatment activity for patients undergoing radioactive iodine 131 I…”
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Noncontrast perfusion single-photon emission CT/CT scanning: a new test for the expedited, high-accuracy diagnosis of acute pulmonary embolism
Published in Chest (01-05-2014)“…Standard ventilation and perfusion (V˙/Q˙) scintigraphy uses planar images for the diagnosis of pulmonary embolism (PE). To evaluate whether tomographic…”
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Higher administered activities of radioactive iodine are associated with less structural persistent response in older, but not younger, papillary thyroid cancer patients with lateral neck lymph node metastases
Published in Thyroid (New York, N.Y.) (01-07-2014)“…While radioactive iodine (RAI) adjuvant therapy is commonly recommended for most papillary thyroid cancer patients presenting with large volume nodal…”
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Recombinant human thyroid stimulating hormone-assisted radioactive iodine remnant ablation in thyroid cancer patients at intermediate to high risk of recurrence
Published in Thyroid (New York, N.Y.) (01-10-2012)“…Multiple studies have demonstrated successful radioactive iodine remnant ablation (RRA) following preparation with recombinant human thyroid stimulating…”
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Enchondroma of Tibia as Potential False-positive Finding on 68Ga-DOTATOC PET/CT Scan
Published in Clinical nuclear medicine (01-01-2019)“…ABSTRACTA 70-year-old man with a history of carcinoid tumor of small bowel was referred for Ga-DOTATOC study to evaluate the extent of disease. PET/CT scan…”
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Patterns of (18)F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET
Published in The Journal of nuclear medicine (1978) (01-11-2003)“…The routine use of PET/CT fusion imaging in a large oncology practice has led to the realization that (18)F-FDG uptake into normal fat and muscle can be a…”
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