Search Results - "Grewal, Annu"
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Clinical side-effects based drug repositioning for anti-epileptic activity
Published in Journal of biomolecular structure & dynamics (11-02-2024)“…Several generations of anti-epileptic drugs (AEDs) are available but have several associated side effects apart from a limited success rate. Drug repositioning…”
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2
Molecular docking analysis of α-Synuclein aggregation with Anle138b
Published in Bioinformation (31-03-2024)“…α-Synuclein aggregation into toxic oligomeric species is central to Parkinson's disease pathogenesis. Anle138b is a recently identified inhibitor of…”
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3
Insights into amyloid precursor protein target through PPI network analysis
Published in Bioinformation (2024)“…Alzheimer's disease (AD) is the leading cause of dementia worldwide with therapeutic lacunae till date. The beta-amyloid (Aβ) accumulation triggers AD…”
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4
Drug repositioning for idiopathic epilepsy using gene expression signature data
Published in Bioinformation (31-10-2022)“…Epilepsy is one of the most common neurological disorders, affecting millions of patients with a substantial economic and human burden. About 30-40% of…”
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5
Molecular docking analysis of marine compounds with voltage gated calcium channel for potential anti-epileptic molecules
Published in Bioinformation (31-03-2024)“…Epileptic seizures are directly linked with an anomalous influx of extracellular calcium or sodium anions through voltage-gated channels disturb the chemical…”
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6
Molecular docking analysis of marine phytochemicals with BACE-1
Published in Bioinformation (01-02-2024)“…Alzheimer's disease (AD), a debilitating neurodegenerative condition, is characterized by progressive cognitive decline brought about by the deposition of…”
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Journal Article -
7
Molecular docking analysis of marine phytochemicals with BACE-1
Published in Bioinformation (2024)“…Alzheimer's disease (AD), a debilitating neurodegenerative condition, is characterized by progressive cognitive decline brought about by the deposition of…”
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Journal Article