Search Results - "Grevitt, Paul"

Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes by Davidson, Kathryn, Grevitt, Paul, Contreras-Gerenas, Maria F., Bridge, Katherine S., Hermida, Miguel, Shah, Kunal M., Mardakheh, Faraz K., Stubbs, Mark, Burke, Rosemary, Casado, Pedro, Cutillas, Pedro R., Martin, Sarah A., Sharp, Tyson V.

“…An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses…”
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A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia by Foxler, Daniel E, Bridge, Katherine S, Foster, John G, Grevitt, Paul, Curry, Sean, Shah, Kunal M, Davidson, Kathryn M, Nagano, Ai, Gadaleta, Emanuela, Rhys, Hefin I, Kennedy, Paul T, Hermida, Miguel A, Chang, Ting‐Yu, Shaw, Peter E, Reynolds, Louise E, McKay, Tristan R, Wang, Hsei‐Wei, Ribeiro, Paulo S, Plevin, Michael J, Lagos, Dimitris, Lemoine, Nicholas R, Rajan, Prabhakar, Graham, Trevor A, Chelala, Claude, Hodivala‐Dilke, Kairbaan M, Spendlove, Ian, Sharp, Tyson V

“…The adaptive cellular response to low oxygen tensions is mediated by the hypoxia‐inducible factors (HIFs), a family of heterodimeric transcription factors…”
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miR‐132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity by Hewitson, James P, Shah, Kunal M, Brown, Najmeeyah, Grevitt, Paul, Hain, Sofia, Newling, Katherine, Sharp, Tyson V, Kaye, Paul M, Lagos, Dimitris

“…Determining the mechanisms that distinguish protective immunity from pathological chronic inflammation remains a fundamental challenge. miR‐132 has been shown…”
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Identification of novel regulators of HIFs for use in anti-cancer target development by Grevitt, Paul

“…Solid tumours display vast heterogeneity in oxygen tension as a consequence of poor vascularization and increased proliferation. Tumour hypoxia (low oxygen) is…”
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The glucose transporter 2 regulates CD8+ T cell function via environment sensing by Fu, Hongmei, Vuononvirta, Juho, Fanti, Silvia, Bonacina, Fabrizia, D’Amati, Antonio, Wang, Guosu, Poobalasingam, Thanushiyan, Fankhaenel, Maria, Lucchesi, Davide, Coleby, Rachel, Tarussio, David, Thorens, Bernard, Hearnden, Robert J., Longhi, M. Paula, Grevitt, Paul, Sheikh, Madeeha H., Solito, Egle, Godinho, Susana A., Bombardieri, Michele, Smith, David M., Cooper, Dianne, Iqbal, Asif J., Rathmell, Jeffrey C., Schaefer, Samuel, Morales, Valle, Bianchi, Katiuscia, Norata, Giuseppe Danilo, Marelli-Berg, Federica M.

“…T cell activation is associated with a profound and rapid metabolic response to meet increased energy demands for cell division, differentiation and…”
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A HIF – LIMD 1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia by Foxler, Daniel E, Bridge, Katherine S, Foster, John G, Grevitt, Paul, Curry, Sean, Shah, Kunal M, Davidson, Kathryn M, Nagano, Ai, Gadaleta, Emanuela, Rhys, Hefin I, Kennedy, Paul T, Hermida, Miguel A, Chang, Ting‐Yu, Shaw, Peter E, Reynolds, Louise E, McKay, Tristan R, Wang, Hsei‐Wei, Ribeiro, Paulo S, Plevin, Michael J, Lagos, Dimitris, Lemoine, Nicholas R, Rajan, Prabhakar, Graham, Trevor A, Chelala, Claude, Hodivala‐Dilke, Kairbaan M, Spendlove, Ian, Sharp, Tyson V

“…The adaptive cellular response to low oxygen tensions is mediated by the hypoxia‐inducible factors (HIFs), a family of heterodimeric transcription factors…”
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Schober Test and Its Modifications Revisited-What Are We Actually Measuring? Computerized Tomography-Based Analysis by Hershkovich, Oded, Grevitt, Michael Paul, Lotan, Raphael

“…Examine Schober test's (ST), Modified ST (MST), and Modified-Modified ST (MMST) surface markers' accuracy in spanning lumbar L1-S1 motion segments and…”
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Posterior-only correction of Scheuermann kyphosis using pedicle screws: economical optimization through screw density reduction by Behrbalk, Eyal, Uri, Ofir, Parks, Ruth M., Grevitt, Michael Paul, Rickert, Marcus, Boszczyk, Bronek Maximilian

“…Introduction Posterior-only approach using pedicle screws’ fixation has emerged as the preferred surgical technique for Scheuermann kyphosis (SK) correction…”
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Percutaneous sacroiliac joint arthrodesis: a novel technique by Al-Khayer, Ahmad, Hegarty, Jim, Hahn, David, Grevitt, Michael Paul

“…Consecutive case series. To report a new percutaneous sacroiliac joint (SIJ) arthrodesis technique utilizing a Hollow Modular Anchorage screw. A variety of SIJ…”
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A study of the radiologic predictors of curve flexibility in adolescent idiopathic scoliosis by Clamp, Jonathan Andrew, Andrews, John Robert, Grevitt, Michael Paul

“…A study of flexibility of 101 idiopathic scoliosis antero-posterior radiographs. To discover if there are any parameters on plain antero-posterior radiographs…”
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