Search Results - "Gretz, Norbert"

miRWalk: An online resource for prediction of microRNA binding sites by Sticht, Carsten, De La Torre, Carolina, Parveen, Alisha, Gretz, Norbert

“…miRWalk is an open-source platform providing an intuitive interface that generates predicted and validated miRNA-binding sites of known genes of human, mouse,…”
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miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes by Dweep, Harsh, Sticht, Carsten, Pandey, Priyanka, Gretz, Norbert

“…miRWalk (http://mirwalk.uni-hd.de/), a comprehensive database that provides predicted as well as validated miRNA binding site information on miRNAs for human,…”
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AutoCellSeg: robust automatic colony forming unit (CFU)/cell analysis using adaptive image segmentation and easy-to-use post-editing techniques by Khan, Arif ul Maula, Torelli, Angelo, Wolf, Ivo, Gretz, Norbert

“…In biological assays, automated cell/colony segmentation and counting is imperative owing to huge image sets. Problems occurring due to drifting image…”
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System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co‐regulation upon iron, sulfur and potassium deficiency by Forieri, Ilaria, Sticht, Carsten, Reichelt, Michael, Gretz, Norbert, Hawkesford, Malcolm J., Malagoli, Mario, Wirtz, Markus, Hell, Ruediger

“…Deprivation of mineral nutrients causes significant retardation of plant growth. This retardation is associated with nutrient‐specific and general…”
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IER2-induced senescence drives melanoma invasion through osteopontin by Kyjacova, Lenka, Saup, Rafael, Rönsch, Kerstin, Wallbaum, Sabine, Dukowic-Schulze, Stefanie, Foss, Amelia, Scherer, Sandra D., Rothley, Melanie, Neeb, Antje, Grau, Nicole, Thiele, Wilko, Thaler, Sonja, Cremers, Natascha, Sticht, Carsten, Gretz, Norbert, Garvalov, Boyan K., Utikal, Jochen, Sleeman, Jonathan P.

“…Expression of the immediate-early response gene IER2 has been associated with the progression of several types of cancer, but its functional role is poorly…”
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YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells by Wei, Teng, Weiler, Sofia Maria Elisabeth, Tóth, Marcell, Sticht, Carsten, Lutz, Teresa, Thomann, Stefan, De La Torre, Carolina, Straub, Beate, Merker, Sabine, Ruppert, Thomas, Marquardt, Jens, Singer, Stephan, Gretz, Norbert, Schirmacher, Peter, Breuhahn, Kai

“…The oncogene yes-associated protein (YAP) is a key modifier of liver homeostasis and regulates mitosis in hepatocytes as well as in malignantly transformed…”
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Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma by Tschaharganeh, Darjus Felix, Chen, Xin, Latzko, Philipp, Malz, Mona, Gaida, Matthias Martin, Felix, Klaus, Ladu, Sara, Singer, Stephan, Pinna, Federico, Gretz, Norbert, Sticht, Carsten, Tomasi, Maria Lauda, Delogu, Salvatore, Evert, Matthias, Fan, Biao, Ribback, Silvia, Jiang, Lijie, Brozzetti, Stefania, Bergmann, Frank, Dombrowski, Frank, Schirmacher, Peter, Calvisi, Diego Francesco, Breuhahn, Kai

“…Background & Aims Cancer cells often lose contact inhibition to undergo anchorage-independent proliferation and become resistant to apoptosis by inactivating…”
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Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart by Jabs, Markus, Rose, Adam J, Lehmann, Lorenz H, Taylor, Jacqueline, Moll, Iris, Sijmonsma, Tjeerd P, Herberich, Stefanie E, Sauer, Sven W, Poschet, Gernot, Federico, Giuseppina, Mogler, Carolin, Weis, Eva-Maria, Augustin, Hellmut G, Yan, Minhong, Gretz, Norbert, Schmid, Roland M, Adams, Ralf H, Gröne, Hermann-Joseph, Hell, Rüdiger, Okun, Jürgen G, Backs, Johannes, Nawroth, Peter P, Herzig, Stephan, Fischer, Andreas

“…BACKGROUND:Nutrients are transported through endothelial cells before being metabolized in muscle cells. However, little is known about the regulation of…”
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Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer by Weiler, Sofia M.E, Pinna, Federico, Wolf, Thomas, Lutz, Teresa, Geldiyev, Aman, Sticht, Carsten, Knaub, Maria, Thomann, Stefan, Bissinger, Michaela, Wan, Shan, Rössler, Stephanie, Becker, Diana, Gretz, Norbert, Lang, Hauke, Bergmann, Frank, Ustiyan, Vladimir, Kalin, Tatiana V, Singer, Stephan, Lee, Ju-Seog, Marquardt, Jens U, Schirmacher, Peter, Kalinichenko, Vladimir V, Breuhahn, Kai

“…Background & Aims Many different types of cancer cells have chromosome instability. The hippo pathway leads to phosphorylation of the transcriptional activator…”
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Transcutaneous measurement of renal function in conscious mice by Schreiber, Andrea, Shulhevich, Yury, Geraci, Stefania, Hesser, Juergen, Stsepankou, Dzmitry, Neudecker, Sabine, Koenig, Stefan, Heinrich, Ralf, Hoecklin, Friederike, Pill, Johannes, Friedemann, Jochen, Schweda, Frank, Gretz, Norbert, Schock-Kusch, Daniel

“…Determination of glomerular filtration rate (GFR) in conscious mice is cumbersome for the experimenter and stressful for the animals. Here we report on a…”
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A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle by Buscone, Serena, Mardaryev, Andrei N., Raafs, Bianca, Bikker, Jan W., Sticht, Carsten, Gretz, Norbert, Farjo, Nilofer, Uzunbajakava, Natallia E., Botchkareva, Natalia V.

“…Background and Objective Though devices for hair growth based on low levels of light have shown encouraging results, further improvements of their efficacy is…”
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NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis by Luiken, Sarah, Fraas, Angelika, Bieg, Matthias, Sugiyanto, Raisatun, Goeppert, Benjamin, Singer, Stephan, Ploeger, Carolin, Warsow, Gregor, Marquardt, Jens U., Sticht, Carsten, De La Torre, Carolina, Pusch, Stefan, Mehrabi, Arianeb, Gretz, Norbert, Schlesner, Matthias, Eils, Roland, Schirmacher, Peter, Longerich, Thomas, Roessler, Stephanie

“…NOTCH receptor signaling plays a pivotal role in liver homeostasis and hepatocarcinogenesis. However, the role of NOTCH pathway mutations and the NOTCH target…”
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Parallel analysis of mRNA and microRNA microarray profiles to explore functional regulatory patterns in polycystic kidney disease: using PKD/Mhm rat model by Dweep, Harsh, Sticht, Carsten, Kharkar, Asawari, Pandey, Priyanka, Gretz, Norbert

“…Autosomal polycystic kidney disease (ADPKD) is a frequent monogenic renal disease, characterised by fluid-filled cysts that are thought to result from multiple…”
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Sulforaphane Promotes Dendritic Cell Stimulatory Capacity Through Modulation of Regulatory Molecules, JAK/STAT3- and MicroRNA-Signaling by Wang, Yangyi, Petrikova, Emilia, Gross, Wolfgang, Sticht, Carsten, Gretz, Norbert, Herr, Ingrid, Karakhanova, Svetlana

“…The broccoli isothiocyanate sulforaphane was shown to inhibit inflammation and tumor progression, also in pancreatic cancer, while its effect on tumor immunity…”
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Evidence for miR-548c-5p regulation of FOXC2 transcription through a distal genomic target site in human podocytes by Christofides, Andrea, Papagregoriou, Gregory, Dweep, Harsh, Makrides, Neoklis, Gretz, Norbert, Felekkis, Kyriacos, Deltas, Constantinos

“…Podocytes are highly differentiated epithelial cells outlining the glomerular vessels. FOXC2 is a transcription factor essential for inducing podocyte…”
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A cationic near infrared fluorescent agent and ethyl-cinnamate tissue clearing protocol for vascular staining and imaging by Huang, Jiaguo, Brenna, Cinzia, Khan, Arif ul Maula, Daniele, Cristina, Rudolf, Rüdiger, Heuveline, Vincent, Gretz, Norbert

“…Understanding vascular structures and dysfunction is a fundamental challenge. This task has been approached by using traditional methodologies such as…”
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Microporous Polylactic Acid Scaffolds Enable Fluorescence-Based Perfusion Imaging of Intrinsic In Vivo Vascularization by Koepple, Christoph, Pollmann, Lukas, Pollmann, Nicola Sariye, Schulte, Matthias, Kneser, Ulrich, Gretz, Norbert, Schmidt, Volker J

“…In vivo tissue engineering (TE) techniques like the AV loop model provide an isolated and well-defined microenvironment to study angiogenesis-related cell…”
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YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis by Thomann, Stefan, Weiler, Sofia M E, Marquard, Simone, Rose, Fabian, Ball, Claudia R, Tóth, Marcell, Wei, Teng, Sticht, Carsten, Fritzsche, Sarah, Roessler, Stephanie, De La Torre, Carolina, Ryschich, Eduard, Ermakova, Olga, Mogler, Carolin, Kazdal, Daniel, Gretz, Norbert, Glimm, Hanno, Rempel, Eugen, Schirmacher, Peter, Breuhahn, Kai

“…The oncogene yes-associated protein (YAP) controls liver tumor initiation and progression via cell extrinsic functions by creating a tumor-supporting…”
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The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis by Moreth, Kristin, Brodbeck, Rebekka, Babelova, Andrea, Gretz, Norbert, Spieker, Tilmann, Zeng-Brouwers, Jinyang, Pfeilschifter, Josef, Young, Marian F, Schaefer, Roland M, Schaefer, Liliana

“…CXCL13 is a key B cell chemoattractant and marker of disease activity in patients with SLE; however, the mechanism of its induction has not been identified…”
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Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness by Wan, Shan, Meyer, Anne‐Sophie, Weiler, Sofia Maria Elisabeth, Rupp, Christian, Tóth, Marcell, Sticht, Carsten, Singer, Stephan, Thomann, Stefan, Roessler, Stephanie, Schorpp‐Kistner, Marina, Schmitt, Jennifer, Gretz, Norbert, Angel, Peter, Tschaharganeh, Darjus Felix, Marquardt, Jens, Schirmacher, Peter, Pinna, Federico, Breuhahn, Kai

“…The loss of epithelial cell polarity plays an important role in the development and progression of liver cancer. However, the specific molecular mechanisms…”
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