Search Results - "Gretch, D R"

Diagnostic tests for hepatitis C by Gretch, D R

“…Diagnostic tests for hepatitis C can be divided into the following two general categories: 1) serological assays that detect antibody to hepatitis C virus…”
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Hepatitis C Viral Dynamics In vivo and the Antiviral Efficacy of Interferon-α Therapy by Neumann, Avidan U., Lam, Nancy P., Dahari, Harel, Gretch, David R., Wiley, Thelma E., Layden, Thomas J., Perelson, Alan S.

“…To better understand the dynamics of hepatitis C virus and the antiviral effect of interferon-α-2b (IFN), viral decline in 23 patients during therapy was…”
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Use of the AST to platelet ratio index in HCV/HIV co‐infected patients by Singal, A. G., Thomassen, L. V., Gretch, D. R., Shuhart, M. C.

“…Aliment Pharmacol Ther 2011; 33: 566–577 Summary Background  The AST to platelet ratio index (APRI), a non‐invasive marker of liver fibrosis, has not been well…”
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Diagnosis and Monitoring of Hepatic Injury. I. Performance Characteristics of Laboratory Tests by Dufour, D. Robert, Lott, John A, Nolte, Frederick S, Gretch, David R, Koff, Raymond S, Seeff, Leonard B

“…To review information on performance characteristics for tests that are commonly used to identify acute and chronic hepatic injury. A MEDLINE search was…”
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Elevated Levels of Interleukin-8 in Serum Are Associated with Hepatitis C Virus Infection and Resistance to Interferon Therapy by Polyak, S J, Khabar, K S, Rezeiq, M, Gretch, D R

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Diagnosis and Monitoring of Hepatic Injury. II. Recommendations for Use of Laboratory Tests in Screening, Diagnosis, and Monitoring by Dufour, D. Robert, Lott, John A, Nolte, Frederick S, Gretch, David R, Koff, Raymond S, Seeff, Leonard B

“…To review information on the use of laboratory tests in screening, diagnosis, and monitoring of acute and chronic hepatic injury. A MEDLINE search was…”
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Hepatitis C Virus Nonstructural 5A Protein Induces Interleukin-8, Leading to Partial Inhibition of the Interferon-Induced Antiviral Response by Polyak, S J, Khabar, K S, Paschal, D M, Ezelle, H J, Duverlie, G, Barber, G N, Levy, D E, Mukaida, N, Gretch, D R

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Prospective Characterization of Full-Length Hepatitis C Virus NS5A Quasispecies during Induction and Combination Antiviral Therapy by Nousbaum, J, Polyak, S J, Ray, S C, Sullivan, D G, Larson, A M, Carithers, Jr, R L, Gretch, D R

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Association of multispecific CD4 + response to hepatitis C and severity of recurrence after liver transplantation by Rosen ,‡, Hugo R., Hinrichs ‡, §, David J., Gretch ∥, David R., Koziel ¶, Margaret J., Chou ,‡, Sunwen, Houghton ##, Michael, Rabkin, John, Corless ‡‡, Christopher L., Bouwer ‡,§, H.G.Archie

“…Background & Aims: After liver transplantation for hepatitis C virus (HCV), reinfection of the allograft invariably occurs. Indirect evidence suggests that the…”
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Dose‐dependent acute clearance of hepatitis C genotype 1 virus with interferon alfa by Lam, N P, Neumann, A U, Gretch, D R, Wiley, T E, Perelson, A S, Layden, T J

“…To determine if the clearance of hepatitis C genotype 1 virus (HCV) is dependent on the dose of interferon alfa‐2b (IFN‐α2b), the acute clearance of HCV after…”
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Transmission of the hepatitis-C virus by tissue transplantation by Conrad, E U, Gretch, D R, Obermeyer, K R, Moogk, M S, Sayers, M, Wilson, J J, Strong, D M

“…The hepatitis-C virus has been the most prevalent cause of chronic hepatitis in both blood and organ recipients. The introduction of a second-generation…”
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High Rate of Spontaneous Negativity for Hepatitis C Virus RNA after Establishment of Chronic Infection in Alaska Natives by Scott, John D., McMahon, Brian J., Bruden, Dana, Sullivan, Daniel, Homan, Chriss, Christensen, Carol, Gretch, David R.

“…Background. Hepatitis C virus (HCV) leads to chronic infection in 70%–85% of exposed patients. Spontaneous clearance of the virus after chronic infection is…”
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Membranoproliferative Glomerulonephritis Associated with Hepatitis C Virus Infection by Johnson, Richard J, Gretch, David R, Yamabe, Hideaki, Hart, Jaime, Bacchi, Carlos E, Hartwell, Peter, Couser, William G, Corey, Lawrence, Wener, Mark H, Alpers, Charles E, Willson, Richard

“…Hepatitis C virus (HCV), an RNA virus first identified in 1989, 1 , 2 is a major cause of both transfusion-associated and sporadic non-A, non-B hepatitis 3 …”
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Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon‐sensitive virus replication by Polyak, Stephen J., Paschal, Denise M., McArdle, Susan, Jr, Michael J., Moradpour, Darius, Gretch, David R.

“…The hepatitis C virus (HCV) nonstructural 5A (NS5A) protein has been implicated in the inherent resistance of HCV to interferon (IFN) antiviral therapy in…”
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Cytomegalovirus viremia : Risk factor for allograft cirrhosis after liver transplantation for hepatitis C by ROSEN, H. R, CHOU, S, CORLESS, C. L, GRETCH, D. R, FLORA, K. D, BOUDOUSQUIE, A, ORLOFF, S. L, RABKIN, J. M, BENNER, K. G

“…Despite recent advances in diagnosis and treatment, cytomegalovirus (CMV) infection continues to be a common cause of morbidity in liver transplant (LT)…”
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Timing and severity of initial hepatitis C recurrence as predictors of long-term liver allograft injury by ROSEN, H. R, GRETCH, D. R, OEHLKE, M, FLORA, K. D, BENNER, K. G, RABKIN, J. M, CORLESS, C. L

“…The majority of patients infected with hepatitis C virus (HCV) undergoing liver transplantation develop evidence of histologic recurrence, and multiple…”
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Persistent hepatitis C virus infection after liver transplantation: clinical and virological features by Gretch, D R, Bacchi, C E, Corey, L, dela Rosa, C, Lesniewski, R R, Kowdley, K, Gown, A, Frank, I, Perkins, J D, Carithers, Jr, R L

“…We report a prospective clinical and virological study of 18 patients undergoing orthotopic liver transplantation, selected because of hepatitis C virus (HCV)…”
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Tracking hepatitis C virus quasispecies major and minor variants in symptomatic and asymptomatic liver transplant recipients by Gretch, D R, Polyak, S J, Wilson, J J, Carithers, Jr, R L, Perkins, J D, Corey, L

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Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes by Lieber, A, He, C Y, Polyak, S J, Gretch, D R, Barr, D, Kay, M A

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Assessment of hepatitis C viremia using molecular amplification technologies : correlations and clinical implications by GRETCH, D. R, DELA ROSA, C, CARITHERS, R. L, WILLSON, R. A, WILLIAMS, B, COREY, L

“…To compare two recently developed molecular techniques for quantitating the levels of hepatitis C virus (HCV) RNA in the serum of patients with a wide spectrum…”
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