Search Results - "Gresser, J"

Atroposelective Synthesis of Axially Chiral Biaryl Compounds by Bringmann, Gerhard, Price Mortimer, Anne J., Keller, Paul A., Gresser, Mary J., Garner, James, Breuning, Matthias

“…A rotationally hindered and thus stereogenic biaryl axis is the structurally and stereochemically decisive element of a steadily growing number of natural…”
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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene by Elchebly, M, Payette, P, Michaliszyn, E, Cromlish, W, Collins, S, Loy, A.L, Normandin, D, Cheng, A, Himms-Hagen, J, Chan, C.C

“…Protein tyrosine phosphatase-1B (PTP-1B) has been implicated in the negative regulation of insulin signaling. Disruption of the mouse homolog of the gene…”
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Combined use of two supervised learning algorithms to model sea turtle behaviours from tri-axial acceleration data by Jeantet, L, Dell'Amico, F, Forin-Wiart, M-A, Coutant, M, Bonola, M, Etienne, D, Gresser, J, Regis, S, Lecerf, N, Lefebvre, F, de Thoisy, B, Le Maho, Y, Brucker, M, Châtelain, N, Laesser, R, Crenner, F, Handrich, Y, Wilson, R, Chevallier, D

“…Accelerometers are becoming ever more important sensors in animal-attached technology, providing data that allow determination of body posture and movement and…”
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Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate by Huyer, G, Liu, S, Kelly, J, Moffat, J, Payette, P, Kennedy, B, Tsaprailis, G, Gresser, M J, Ramachandran, C

“…Vanadate and pervanadate (the complexes of vanadate with hydrogen peroxide) are two commonly used general protein-tyrosine phosphatase (PTP) inhibitors. These…”
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Versatility of biodegradable biopolymers: degradability and an in vivo application by Hasırcı, V., Lewandrowski, K., Gresser, J.D., Wise, D.L., Trantolo, D.J.

“…Biodegradable materials have various important applications in the biomedical field. There are basically two groups of polyesters which have significant…”
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Bioresorbable bone graft substitutes of different osteoconductivities: a histologic evaluation of osteointegration of poly(propylene glycol-co-fumaric acid)-based cement implants in rats by Lewandrowski, Kai-Uwe, D. Gresser, Joseph, Wise, Donald L, Trantolo, Debra J

“…Bioresorbable bone graft substitutes may significantly reduce the disadvantages associated with autografts, allografts and other synthetic materials currently…”
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Dissecting the Cofactor-Dependent and Independent Bindings of PDE4 Inhibitors by Liu, Susana, Laliberté, France, Bobechko, Brian, Bartlett, Adrienne, Lario, Paula, Gorseth, Elise, Van Hamme, Jonathan, Gresser, Michael J, Huang, Zheng

“…Type 4 phosphodiesterases (PDE4s) are metallohydrolases that catalyze the hydrolysis of cAMP to AMP. At the bottom of its active site lie two divalent metal…”
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Catalytic Inactivation of Protein Tyrosine Phosphatase CD45 and Protein Tyrosine Phosphatase 1B by Polyaromatic Quinones by Wang, Qingping, Dubé, Daniel, Friesen, Richard W, LeRiche, Tammy G, Bateman, Kevin P, Trimble, Laird, Sanghara, Joe, Pollex, Rebecca, Ramachandran, Chidambaram, Gresser, Michael J, Huang, Zheng

“…Polyaromatic quinones, such as the environmental pollutants 9,10-phenanthrenediones, elicit a wide range of responses including growth inhibition, immune…”
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How Does Alendronate Inhibit Protein-tyrosine Phosphatases? by Skorey, Kathryn, Ly, Hoa D., Kelly, John, Hammond, Mike, Ramachandran, Chidambaram, Huang, Zheng, Gresser, Michael J., Wang, Qingping

“…Alendronate (4-amino-1-hydroxybutylidene 1,1-bisphosphonate) is a drug used in the treatment of osteoporosis and other bone diseases. The inhibition of…”
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Monotonicity of interleukin-1 receptor–ligand binding with respect to antagonist in the presence of decoy receptor by Gnacadja, Gilles, Shoshitaishvili, Alex, Gresser, Michael J., Varnum, Brian, Balaban, David, Durst, Mark, Vezina, Chris, Li, Yu

“…We consider the interaction between interleukin-1 IL-1, its receptor IL-1RI, the receptor antagonist IL-1Ra and a decoy receptor (or trap) that binds both with…”
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Osteoconductivity of an injectable and bioresorbable poly(propylene glycol-co-fumaric acid) bone cement by Lewandrowski, Kai-Uwe, Gresser, Joseph D, Wise, Donald L, White, Roslyn L, Trantolo, Debra J

“…We have investigated an injectable form of a resorbable bone cement based on in situ crosslinking of the unsaturated polyester, poly(propylene…”
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Bis(N,N-dimethylhydroxamido)hydroxooxovanadate inhibition of protein tyrosine phosphatase activity in intact cells: comparison with vanadate by Cuncic, Cary, Desmarais, Sylvie, Detich, Nancy, Tracey, Alan S, Gresser, Michael J, Ramachandran, Chidambaram

“…We have shown previously that bis(N,N-dimethylhydroxamido)hydroxooxovanadate (DMHV) is an excellent reversible inhibitor of protein tyrosine phosphatase (PTP)…”
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Calcium Is Not Required for 5-Lipoxygenase Activity at High Phosphatidyl Choline Vesicle Concentrations by Skorey, Kathryn I, Gresser, Michael J

“…5-Lipoxygenase (5-LO) catalyzes the formation of 5-hydroperoxy-eicosatetraenoic acid (5-HPETE) and leukotriene A4 (LTA4) from arachidonic acid. Following a…”
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The attempted stereoselective synthesis of chiral 2,2′-biindoline by Gresser, Mary J., Wales, Steven M., Keller, Paul A.

“…The attempted first stereoselective synthesis of 2,2′-biindoline using a metathesis-Sharpless asymmetric dihydroxylation strategy results in the synthesis of…”
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Developing porosity of poly(propylene glycol-co-fumaric acid) bone graft substitutes and the effect on osteointegration: A preliminary histology study in rats by Lewandrowski, Kai-Uwe, Gresser, Joseph D., P.Bondre, Shrikar, Silva, Alyson E., Wise, Donald L., Trantolo, Debra J.

“…Abstract -Bioresorbable bone graft substitutes could eliminate disadvantages associated with the use of autografts, allografts and other synthetic materials…”
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Affinity Selection from Peptide Libraries to Determine Substrate Specificity of Protein Tyrosine Phosphatases by Huyer, Gregory, Kelly, John, Moffat, Jason, Zamboni, Robert, Jia, Zongchao, Gresser, Michael J., Ramachandran, Chidambaram

“…Affinity selection from peptide libraries is a powerful tool that has been used for determining the sequence specificities of a number of enzymes and protein…”
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Novel caged fluorescein diphosphates as photoactivatable substrates for protein tyrosine phosphatases by Wang, Qingping, Scheigetz, John, Roy, Bruno, Ramachandran, Chidambaram, Gresser, Michael J

“…We have characterized some novel caged fluorescein diphosphates as photoactivatable, cell-permeable substrates for protein tyrosine phosphatases and explored…”
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In vitro PKA phosphorylation-mediated human PDE4A4 activation by Laliberté, France, Liu, Susana, Gorseth, Elise, Bobechko, Brian, Bartlett, Adrienne, Lario, Paula, Gresser, Michael J, Huang, Zheng

“…The PDE4 catalytic machinery comprises, in part, two divalent cations in a binuclear motif. Here we report that PDE4A4 expressed in Sf9 cells exhibits a…”
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Interaction of Vanadate with Phenol and Tyrosine: Implications for the Effects of Vanadate on Systems Regulated by Tyrosine Phosphorylation by Tracey, Alan S., Gresser, Michael J.

“…The interaction of vanadate with phenol and N-acetyltyrosine ethyl ester in aqueous solution has been studied by using 51V nuclear magnetic resonance…”
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PLGA bone plates reinforced with crosslinked PPF by Hasirci, V, Litman, A E, Trantolo, D J, Gresser, J D, Wise, D L, Margolis, H C

“…In this study a matrix of poly(propylene fumarate) (PPF) was crosslinked with N-vinylpyrrolidone (NVP), 2-hydroxyethylmethacrylate (HEMA), or a mixture of NVP…”
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