Search Results - "Grenz, Almut"

Hypoxia and inflammation are two sides of the same coin by Bartels, Karsten, Grenz, Almut, Eltzschig, Holger K.

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Perioperative Organ Injury by BARTELS, Karsten, KARHAUSEN, Jörn, CLAMBEY, Eric T, GRENZ, Almut, ELTZSCHIG, Holger K

“…Despite the fact that a surgical procedure may have been performed for the appropriate indication and in a technically perfect manner, patients are threatened…”
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Interleukin 37 expression protects mice from colitis by McNamee, Eóin N, Masterson, Joanne C, Jedlicka, Paul, McManus, Martine, Grenz, Almut, Collins, Colm B, Nold, Marcel F, Nold-Petry, Claudia, Bufler, Philip, Dinarello, Charles A, Rivera-Nieves, Jesús

“…IL-37, a newly described member of the IL-1 family, functions as a fundamental inhibitor of innate inflammation and immunity. In the present study, we examined…”
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A2B adenosine receptor dampens hypoxia-induced vascular leak by Eckle, Tobias, Faigle, Marion, Grenz, Almut, Laucher, Stefanie, Thompson, Linda F., Eltzschig, Holger K.

“…Extracellular adenosine has been implicated in adaptation to hypoxia and previous studies demonstrated a central role in vascular responses. Here, we examined…”
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Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease by Poth, Jens M., Brodsky, Kelley, Ehrentraut, Heidi, Grenz, Almut, Eltzschig, Holger K.

“…Inflammatory lesions, ischemic tissues, or solid tumors are characterized by the occurrence of severe tissue hypoxia within the diseased tissue. Subsequent…”
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Adenosine Generation and Signaling during Acute Kidney Injury by BAUERLE, Jessica D, GRENZ, Almut, KIM, Jae-Hwan, LEE, H. Thomas, ELTZSCHIG, Holger K

“…Acute kidney injury (AKI) is among the leading causes of morbidity and mortality in hospitalized patients. Particularly in the perioperative period, the most…”
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Detrimental effects of adenosine signaling in sickle cell disease by Xia, Yang, Zhang, Yujin, Dai, Yingbo, Wen, Jiaming, Zhang, Weiru, Grenz, Almut, Sun, Hong, Tao, Lijian, Lu, Guangxiu, Alexander, Danny C, Milburn, Michael V, Carter-Dawson, Louvenia, Lewis, Dorothy E, Zhang, Wenzheng, Eltzschig, Holger K, Kellems, Rodney E, Blackburn, Michael R, Juneja, Harinder S

“…Yujin Zhang et al . discovered that the concentration of adenosine in the blood is increased both in a mouse model of sickle cell disease and in humans with…”
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The reno-vascular A2B adenosine receptor protects the kidney from ischemia by Grenz, Almut, Osswald, Hartmut, Eckle, Tobias, Yang, Dan, Zhang, Hua, Tran, Zung Vu, Klingel, Karin, Ravid, Katya, Eltzschig, Holger K

“…Acute renal failure from ischemia significantly contributes to morbidity and mortality in clinical settings, and strategies to improve renal resistance to…”
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Netrin-1 controls sympathetic arterial innervation by Brunet, Isabelle, Gordon, Emma, Han, Jinah, Cristofaro, Brunella, Broqueres-You, Dong, Liu, Chun, Bouvrée, Karine, Zhang, Jiasheng, del Toro, Raquel, Mathivet, Thomas, Larrivée, Bruno, Jagu, Julia, Pibouin-Fragner, Laurence, Pardanaud, Luc, Machado, Maria J C, Kennedy, Timothy E, Zhuang, Zhen, Simons, Michael, Levy, Bernard I, Tessier-Lavigne, Marc, Grenz, Almut, Eltzschig, Holger, Eichmann, Anne

“…Autonomic sympathetic nerves innervate peripheral resistance arteries, thereby regulating vascular tone and controlling blood supply to organs. Despite the…”
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CD39/Ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury by KÖHLER, David, ECKLE, Tobias, FAIGLE, Marion, GRENZ, Almut, MITTELBRONN, Michel, LAUCHER, Stefanie, HART, Melanie L, ROBSON, Simon C, MÜLLER, Christa E, ELTZSCHIG, Holger K

“…Extracellular adenosine, generated from extracellular nucleotides via ectonucleotidases, binds to specific receptors and provides cardioprotection from…”
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Elevated Ecto-5ʼ-nucleotidase-Mediated Increased Renal Adenosine Signaling Via A2B Adenosine Receptor Contributes to Chronic Hypertension by Zhang, Weiru, Zhang, Yujin, Wang, Wei, Dai, Yingbo, Ning, Chen, Luo, Renna, Sun, Kaiqi, Glover, Louise, Grenz, Almut, Sun, Hong, Tao, Lijian, Zhang, Wenzheng, Colgan, Sean P, Blackburn, Michael R, Eltzschig, Holger K, Kellems, Rodney E, Xia, Yang

“…RATIONALE:Hypertension is the most prevalent life-threatening disease worldwide and is frequently associated with chronic kidney disease (CKD). However, the…”
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Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia by GRENZ, Almut, HUA ZHANG, ECKLE, Tobias, MITTELBRONN, Michel, WEHRMANN, Manfred, KOHLE, Christoph, KLOOR, Doris, THOMPSON, Linda F, OSSWALD, Hartmut, ELTZSCHIG, Holger K

“…Acute renal failure from ischemia significantly contributes to cardiovascular morbidity and mortality. Extracellular adenosine has been implicated as an…”
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Signaling through hepatocellular A2B adenosine receptors dampens ischemia and reperfusion injury of the liver by Zimmerman, Michael A., Grenz, Almut, Tak, Eunyoung, Kaplan, Maria, Ridyard, Douglas, Brodsky, Kelley S., Mandell, Mercedes Susan, Kam, Igal, Eltzschig, Holger K.

“…Ischemia and reperfusion significantly contributes to the morbidity and mortality of liver surgery and transplantation. Based on studies showing a critical…”
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Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice by Eckle, Tobias, Grenz, Almut, Köhler, David, Redel, Andreas, Falk, Melanie, Rolauffs, Bernd, Osswald, Hartmut, Kehl, Franz, Eltzschig, Holger K

“…Cardioprotection by ischemic preconditioning (IP) remains an area of intense investigation. To further elucidate its molecular basis, the use of transgenic…”
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SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy by Wang, Xiaoxin X., Levi, Jonathan, Luo, Yuhuan, Myakala, Komuraiah, Herman-Edelstein, Michal, Qiu, Liru, Wang, Dong, Peng, Yingqiong, Grenz, Almut, Lucia, Scott, Dobrinskikh, Evgenia, D'Agati, Vivette D., Koepsell, Hermann, Kopp, Jeffrey B., Rosenberg, Avi Z., Levi, Moshe

“…There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature…”
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Partial netrin-1 deficiency aggravates acute kidney injury by Grenz, Almut, Dalton, Julee H, Bauerle, Jessica D, Badulak, Alexander, Ridyard, Douglas, Gandjeva, Aneta, Aherne, Carol M, Brodsky, Kelley S, Kim, Jae-Hwan, Tuder, Rubin M, Eltzschig, Holger K

“…The netrin family of secreted proteins provides migrational cues in the developing central nervous system. Recently, netrins have also been shown to regulate…”
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Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge by Rose, Jennifer B., Naydenova, Zlatina, Bang, Andrew, Ramadan, Azza, Klawitter, Jost, Schram, Kristin, Sweeney, Gary, Grenz, Almut, Eltzschig, Holger, Hammond, James, Choi, Doo-Sup, Coe, Imogen R.

“…Equilibrative nucleoside transporters (ENT) modulate the flux of adenosine. The ENT1-null (KO) mouse heart is endogenously cardioprotected but the cellular…”
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Hypoxia signaling during intestinal ischemia and inflammation by Grenz, Almut, Clambey, Eric, Eltzschig, Holger K.

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Resveratrol Binds to the Sulfonylurea Receptor (SUR) and Induces Apoptosis in a SUR Subtype-specific Manner by Hambrock, Annette, de Oliveira Franz, Claudia Bernardo, Hiller, Sabrina, Grenz, Almut, Ackermann, Stefanie, Schulze, Dorothea U., Drews, Gisela, Osswald, Hartmut

“…Sulfonylurea receptors (SURs) constitute the regulatory subunits of ATP-sensitive K+ channels (KATP channels). SUR binds nucleotides and synthetic KATP channel…”
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Usefulness of pressure-controlled ventilation at high inspiratory pressures to induce acute lung injury in mice by Eckle, Tobias, Füllbier, Lars, Grenz, Almut, Eltzschig, Holger K

“…Acute lung injury (ALI), as occurs with prolonged mechanical ventilation, contributes to morbidity and mortality of critical illness, and studies on novel…”
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