Search Results - "Grenley, M.O."

A Phase 0 Master Protocol Utilizing a Novel Intratumoral Microdosing Approach for Simultaneously Evaluating Multiple Drugs and Drug Combinations in Patients with Solid Tumors by Ow, T.J., Mehta, V., Gersten, A.J., Newman, J.G., Maki, R.G., Gundle, K.R., Clayburgh, D.R., Li, R.J., Porosnicu, M., Nathan, C.A.O., Hatton, B.A., Sottero, K.H.W., Kung, G., Grenley, M.O., Anderson, K., Klinghoffer, R.A.

“…Tumor responses to cancer treatments are highly context-specific and often involve complex interactions between the anti-cancer therapy, genetically diverse…”
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A Novel Intratumoral Microdosing Approach for Simultaneously Evaluating Multiple Drugs and Combinations in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) by Houlton, J., Cash, H., Xu, H., Swiecicki, P.L., Chinn, S.B., Clayburgh, D.R., Li, R.J., Christian, R.J., Halfpenny, A., vanZante, A., Hatton, B.A., Sottero, K.H.W., Kung, G., Grenley, M.O., Burns, C., Beirne, E., Klinghoffer, R.A., Huszar, D., Berger, A., Kannan, K.

“…A fundamental issue in cancer drug development is the discordance between robust anti-tumor efficacy observed in laboratory models and the inadequate…”
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