Search Results - "Grenfell, Rafaella Fortini"
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Evaluation of schistosomula crude antigen (SCA) as a diagnostic tool for Schistosoma mansoni in low endemic human population
Published in Scientific reports (18-05-2021)“…The study aimed to determine the potential of schistosomula crude antigen (SCA) as a diagnostic target for anti- S. mansoni antibody detection. Cercariae were…”
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Schistosomiasis in Nigeria: Gleaning from the past to improve current efforts towards control
Published in One health (20-12-2020)“…The effort to control schistosomiasis in Nigeria has been scaled up the past few years. Schistosomiasis affects all age groups, however, school children are at…”
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Improvement of POC-CCA Interpretation by Using Lyophilization of Urine from Patients with Schistosoma mansoni Low Worm Burden: Towards an Elimination of Doubts about the Concept of Trace
Published in PLoS neglected tropical diseases (21-06-2016)“…Accurate diagnostic techniques for schistosomiasis are essential for prevalence determination and identification of positive patients. A point-of-care test for…”
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Diagnosis of Schistosoma mansoni infections: what are the choices in Brazilian low-endemic areas?
Published in Memórias do Instituto Oswaldo Cruz (28-03-2019)“…The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the…”
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Serological proteomic screening and evaluation of a recombinant egg antigen for the diagnosis of low-intensity Schistosoma mansoni infections in endemic area in Brazil
Published in PLoS neglected tropical diseases (01-03-2019)“…Despite decades of use of control programs, schistosomiasis remains a global public health problem. To further reduce prevalence and intensity of infection, or…”
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Newly established monoclonal antibody diagnostic assays for Schistosoma mansoni direct detection in areas of low endemicity
Published in PloS one (31-01-2014)“…Current available methods for diagnosis of schistosomiasis mansoni lack sufficient sensitivity, which results in underreporting of infectious in areas of low…”
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Rapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2023)“…SARS-CoV-2 virus originated in Wuhan (China) in December (2019) and quickly spread worldwide. Antigen tests are rapid diagnostic tests (RDT) that produce…”
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Synthetic Aurones: New Features for Schistosoma mansoni Therapy
Published in Chemistry & biodiversity (01-11-2021)“…In this work, two synthetic aurones revealed moderate schistosomicidal potential in in vitro and in vivo assays. Aurones (1) and (2) promoted changes in…”
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Access to COVID-19 vaccines and testing in Africa: the importance of COVAX - Nigeria as a case study
Published in Pathogens and global health (17-02-2023)“…Since pandemic declaration, the vulnerability of countries with serious economic challenges and limited health resources became evident. This vulnerability has…”
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Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms
Published in Memórias do Instituto Oswaldo Cruz (01-08-2013)“…Current schistosomiasis control strategies are largely based on chemotherapeutic agents and a limited number of drugs are available today. Praziquantel (PZQ)…”
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Schistosoma mansoni in a low-prevalence area in Brazil: the importance of additional methods for the diagnosis of hard-to-detect individual carriers by low-cost immunological assays
Published in Memórias do Instituto Oswaldo Cruz (01-05-2013)“…Schistosomiasis diagnosis is based on the detection of eggs in the faeces, which is laborious and lacks sensitivity, especially for patients with a low…”
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12
Immunodiagnostic Methods : What Is Their Role in Areas of Low Endemicity?
Published in TheScientificWorld (01-01-2012)“…Worldwide Schistosomiasis mansoni continues to be a serious public health problem. Over the past decades, control programmes have made remarkable progress in…”
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Acute schistosomiasis diagnosis: a new tool for the diagnosis of schistosomiasis in a group of travelers recently infected in a new focus of Schistosoma mansoni
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-03-2013)“…The diagnosis of schistosomiasis mansoni on early stages of infection is important to prevent late morbidity. A simple, cheap, sensitive and specific assay for…”
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Antigens of worms and eggs showed a differentiated detection of specific IgG according to the time of Schistosoma mansoni infection in mice
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-07-2012)“…The correlation between the immunological assay and the antibody titer can offer a tool for the experimental analysis of different phases of the disease. Two…”
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Biomarkers for schistosomiasis: Towards an integrative view of the search for an effective diagnosis
Published in Acta tropica (01-04-2014)“…We present an overview of all relevant investigations designed for the identification of proteins as markers for the schistosomiasis diagnosis. [Display…”
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Variant-dependent oxidative and cytokine responses of human neutrophils to SARS-CoV-2 spike protein and anti-spike IgG1 antibodies
Published in Frontiers in immunology (16-10-2023)“…Severe forms of COVID-19, the disease caused by SARS-CoV-2, are characterized by acute respiratory distress syndrome, robust lung inflammation and death in…”
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Anti-mitochondrial Tryparedoxin Peroxidase Monoclonal Antibody-Based Immunohistochemistry for Diagnosis of Cutaneous Leishmaniasis
Published in Frontiers in microbiology (28-02-2022)“…Cutaneous leishmaniasis (CL) remains a globally spreading public health problem. Among Latin America countries, Brazil has the greatest number of recorded CL…”
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Second booster dose improves antibody neutralization against BA.1, BA.5 and BQ.1.1 in individuals previously immunized with CoronaVac plus BNT162B2 booster protocol
Published in Frontiers in cellular and infection microbiology (04-04-2024)“…SARS-CoV-2 vaccines production and distribution enabled the return to normalcy worldwide, but it was not fast enough to avoid the emergence of variants capable…”
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Booster dose of BNT162b2 after two doses of CoronaVac improves neutralization of SARS-CoV-2 Omicron variant
Published in Communications medicine (29-06-2022)“…Background The emergence of the new SARS-CoV-2 Omicron variant, which is known to have a large number of mutations when compared to other variants, brought to…”
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In vitro assessment of neutrophil response to proteins and antibodies of SARS-CoV-2
Published in The Journal of immunology (1950) (01-05-2022)“…The SARS-CoV-2 virus caused a worldwide epidemic of respiratory disease (COVID-19). Acute respiratory distress syndrome (ARDS) has been associated with severe…”
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