Search Results - "Gremião, Maria Palmira Daflon"
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Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease
Published in International Journal of Nanomedicine (01-01-2015)“…Alzheimer's disease is a neurological disorder that results in cognitive and behavioral impairment. Conventional treatment strategies, such as…”
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Gellan Gum/Pectin Beads Are Safe and Efficient for the Targeted Colonic Delivery of Resveratrol
Published in Polymers (08-01-2018)“…This work addresses the establishment and characterization of gellan gum:pectin (GG:P) biodegradable mucoadhesive beads intended for the colon-targeted…”
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Bioadhesive Surfactant Systems for Methotrexate Skin Delivery
Published in Molecules (Basel, Switzerland) (18-02-2016)“…Methotrexate (MTX) is an immunosuppressive drug for systemic use in the treatment of skin diseases, however, MTX presents a number of side effects, such as…”
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Design, characterization, and biological evaluation of curcumin-loaded surfactant-based systems for topical drug delivery
Published in International journal of nanomedicine (01-01-2016)“…From previous studies, it has been found that curcumin exhibits an anti-inflammatory activity and is being used for the treatment of skin disorders; however,…”
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Nanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A Review
Published in BioMed research international (01-01-2015)“…Melanoma (MEL) is a less common type of skin cancer, but it is more aggressive with a high mortality rate. The World Cancer Research Fund International…”
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Preparation and Characterization of Chitosan Nanoparticles for Zidovudine Nasal Delivery
Published in Journal of nanoscience and nanotechnology (01-01-2015)“…Zidovudine (AZT) is the antiretroviral drug most frequently used for the treatment of Acquired Immunodeficiency Syndrome. Its low oral bioavailability demands…”
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An Inhalable Powder Formulation Based on Micro- and Nanoparticles Containing 5-Fluorouracil for the Treatment of Metastatic Melanoma
Published in Nanomaterials (Basel, Switzerland) (30-01-2018)“…Melanoma is the most aggressive and lethal type of skin cancer, with a poor prognosis because of the potential for metastatic spread. The aim was to develop…”
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Rapid and Sensitive Analytical Method for the Determination of Insulin in Liposomes by Reversed-Phase HPLC
Published in Acta chimica Slovenica (01-12-2020)“…Insulin is an important anabolic hormone that regulates the metabolism of carbohydrates, lipids and proteins. In this study, a reverse-phase liquid…”
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Mucoadhesive nanostructured polyelectrolytes complexes modulate the intestinal permeability of methotrexate
Published in European journal of pharmaceutical sciences (01-01-2018)“…Nanostructured polyelectrolytes complexes (nano PECs) loaded with methotrexate (MTX) were obtained by the polyelectrolyte complexation of chitosan (CS) and…”
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Polymeric-based drug delivery systems for veterinary use: State of the art
Published in International journal of pharmaceutics (15-07-2021)“…[Display omitted] •Review about the main drug delivery systems based on polymers for veterinary use.•Challenges and opportunities in the field of…”
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Nasal administration of liquid crystal precursor mucoadhesive vehicle as an alternative antiretroviral therapy
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2013)“…This study developed a low viscosity precursor of a liquid crystal phase to obtain a mucoadhesive stimuli-sensitive drug delivery system for nasal…”
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Synthesis and factorial design applied to a novel chitosan/sodium polyphosphate nanoparticles via ionotropic gelation as an RGD delivery system
Published in Carbohydrate polymers (10-02-2017)“…•This works shows how to obtain chitosan nanoparticles with sodium polyphosphate.•Chitosan/polyphosphate nanoparticles were optimized using a 32 factorial…”
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A simple reversed phase high-performance liquid chromatography (HPLC) method for determination of in situ gelling curcumin-loaded liquid crystals in in vitro performance tests
Published in Arabian journal of chemistry (01-11-2017)“…A simple, rapid, and sensitive analytical procedure has been developed and validated for the in vitro measurement of curcumin in samples from mucosae retention…”
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Mucoadhesive drug delivery systems
Published in Brazilian Journal of Pharmaceutical Sciences (01-03-2010)“…Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the…”
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Biopharmaceutical and nanotoxicological aspects of cyclodextrins for non-invasive topical treatments: A critical review
Published in Journal of applied toxicology (01-10-2023)“…Cyclodextrins are nanometric cyclic oligosaccharides with amphiphilic characteristics that increase the stability of drugs in pharmaceutical forms and…”
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A Critical Review of Biological Properties, Delivery Systems and Analytical/Bioanalytical Methods for Determination of Bevacizumab
Published in Critical reviews in analytical chemistry (2021)“…Bevacizumab is a chimeric monoclonal human-murine antibody originated from murine monoclonal antibody (muMAb A4.6.1) with the human immunoglobulin IgG1. BVZ…”
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Preparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel
Published in Brazilian Journal of Pharmaceutical Sciences (01-03-2013)“…A hydrogel was developed from 70 kDa dextran (DEX-70) and praziquantel (PZQ) incorporated as a model drug. Biopharmaceutical properties, such as solubility and…”
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Semiochemical delivery systems based on natural polymers to attract sand flies (Diptera: Psychodidae)
Published in Parasites & vectors (29-08-2023)“…Abstract Background The successful use of semiochemicals to attract insects to traps is based on research on the most suitable compounds and their release…”
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Liposomes and micro/nanoparticles as colloidal carriers for nasal drug delivery
Published in Current drug delivery (01-07-2006)“…The use of the nasal route for drug delivery has attracted much interest in recent years in the pharmaceutical field. Local and principally systemic drug…”
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Cellulose triacetate films obtained from sugarcane bagasse: Evaluation as coating and mucoadhesive material for drug delivery systems
Published in Carbohydrate polymers (05-11-2016)“…•Cellulose triacetate (CTA) films were produced from cellulose extracted sugarcane bagasse.•Films showed potential for using as coating and…”
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