Search Results - "Grell, Tsehai A.J."

A Rich Man, Poor Man Story of S-Adenosylmethionine and Cobalamin Revisited by Bridwell-Rabb, Jennifer, Grell, Tsehai A.J, Drennan, Catherine L

“…S -adenosylmethionine (AdoMet) has been referred to as both "a poor man's adenosylcobalamin (AdoCbl)" and "a rich man's AdoCbl," but today, with the…”
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Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer by Grell, Tsehai A.J., Mason, Mark, Thompson, Aaron A., Gómez-Tamayo, Jose Carlos, Riley, Daniel, Wagner, Michelle V., Steele, Ruth, Ortiz-Meoz, Rodrigo F., Wadia, Jay, Shaffer, Paul L., Tresadern, Gary, Sharma, Sujata, Yu, Xiaodi

“…Malic enzymes (ME1, ME2, and ME3) are involved in cellular energy regulation, redox homeostasis, and biosynthetic processes, through the production of pyruvate…”
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Rapid crystallization of glycine using metal-assisted and microwave-accelerated evaporative crystallization: the effect of engineered surfaces and sample volume by Grell, Tsehai A J, Pinard, Melissa A, Pettis, Danielle, Aslan, Kadir

“…Metal-Assisted and Microwave-Accelerated Evaporative Crystallization (MA-MAEC), is a new approach to crystallization of drug compounds, amino acids, DNA and…”
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Quantitative Comparison of Protein Surface Coverage on Glass Slides and Silver Island Films in Metal-Enhanced Fluorescence-based Biosensing Applications by Grell, Tsehai A J, Paredes, Eduardo, Das, Subha R, Aslan, Kadir

“…The use of Metal-Enhanced Fluorescence (MEF) phenomenon in fluorescence-based bioassays affords for increased sensitivity to be realized by incorporating metal…”
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SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes by Grell, Tsehai A.J., Goldman, Peter J., Drennan, Catherine L.

“…S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-4S] cluster to catalyze a diverse array of reactions. They adopt a partial…”
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Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase by Grell, Tsehai A.J., Kincannon, William M., Bruender, Nathan A., Blaesi, Elizabeth J., Krebs, Carsten, Bandarian, Vahe, Drennan, Catherine L.

“…Sactipeptides are a subclass of ribosomally synthesized and post-translationally modified peptides (RiPPs). They contain a unique thioether bond, referred to…”
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7‑Carboxy-7-deazaguanine Synthase: A Radical S‑Adenosyl‑l‑methionine Enzyme with Polar Tendencies by Bruender, Nathan A, Grell, Tsehai A. J, Dowling, Daniel P, McCarty, Reid M, Drennan, Catherine L, Bandarian, Vahe

“…Radical S-adenosyl-l-methionine (SAM) enzymes are widely distributed and catalyze diverse reactions. SAM binds to the unique iron atom of a site-differentiated…”
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Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4‑Demethylwyosine by TYW1 by Grell, Tsehai A. J, Young, Anthony P, Drennan, Catherine L, Bandarian, Vahe

“…TYW1 is a radical S-adenosyl-l-methionine (SAM) enzyme that catalyzes the condensation of pyruvate and N-methylguanosine to form the posttranscriptional…”
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Crystal structure of AdoMet radical enzyme 7‐carboxy‐7‐deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe–4S] cluster engender flavodoxin specificity by Grell, Tsehai A.J., Bell, Benjamin N., Nguyen, Chi, Dowling, Daniel P., Bruender, Nathan A., Bandarian, Vahe, Drennan, Catherine L.

“…7‐Carboxy‐7‐deazaguanine synthase, QueE, catalyzes the radical mediated ring contraction of 6‐carboxy‐5,6,7,8‐tetrahydropterin, forming the characteristic…”
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Rapid and Sensitive Detection of Troponin I in Human Whole Blood Samples by Using Silver Nanoparticle Films and Microwave Heating by ASLAN, Kadir, GRELL, Tsehai A. J

“…Cardiovascular diseases are among the leading causes of mortality in developed countries. It is widely recognized that troponin I (TnI) can be used for the…”
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Microwave-Accelerated Surface Modification of Plasmonic Gold Thin Films with Self-Assembled Monolayers of Alkanethiols by Grell, Tsehai A. J, Alabanza, Anginelle M, Gaskell, Karen, Aslan, Kadir

“…A rapid surface modification technique for the formation of self-assembled monolayers (SAMs) of alkanethiols on gold thin films using microwave heating in <10…”
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